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Gut Microbe, Prevotella copri, Implicated in RA Pathogenesis

Kathy Holliman  |  August 13, 2017

New research reinforces the hypothesis that the gut microbiome triggers mucosal and systemic immune responses in patients with rheumatoid arthritis. The research, published in Arthritis & Rheumatology May 2017, found that subgroups of patients with RA have differential immunoglobulin G (IgG) or IgA immune reactivity with Prevotella copri, an intestinal microbe that appears to be…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:ACR JournalAmerican College of Rheumatology (ACR)DiagnosisgutmicrobeMicrobiomePathogenesispatient carePrevotella copriRAResearchRheumatic DiseaseRheumatoid arthritisrheumatologistrheumatologyTreatment

Effectiveness of Retinoic Acid, Hydroxychloroquine Examined for Hand OA

Lindsey MacFarlane, MD, MPH  |  August 13, 2017

The Osteoarthritis Research Society International (OARSI) held the 2017 OARSI World Congress in Las Vegas, April 27–30. Below, we report on two of the sessions held. Retinoic Acid & Hand Osteoarthritis Retinoic acid is a vitamin A derivative and hormonal signaling molecule with a role in cartilage and skeletal development. Retinoic acid has complex function,…

Filed under:ConditionsMeeting ReportsOsteoarthritis and Bone DisordersResearch Rheum Tagged with:2017 OARSI World Congresshand osteoarthritisHYDROXYCHLOROQUINEOsteoarthritis Research Society InternationalResearchretinoic acidrheumatologystudiessymptomsTreatment

Fellows’ Forum Case Report: Tophaceous Bullae

Mark Vercel, DO, Kim Reinhart, OMS-3, & Amita Thakkar, MD  |  August 13, 2017

As a manifestation of hyperuricemia, inflammatory bullous lesions have rarely been described in the past century. A more classic presentation of hyperuricemia is acute inflammatory gouty arthritis, characterized by the deposition of monosodium urate crystals. Other complications of chronic untreated hyperuricemia may include polyarticular arthritis, tophus formation and possible chronic destructive lesions of the bone,…

Filed under:Conditions Tagged with:case reportClinicalFellowsFellows ForumoutcomeRheumatic DiseaserheumatologyTophaceous Bullae

Is an Arthritis Vaccine Using Genetically Reprogrammed Stem Cells on the Horizon?

Elizabeth Hofheinz, MPH, MEd  |  August 13, 2017

The words genetically modified are making people run for the hills these days. Not so when it comes to arthritis care, however. In the lab of one pioneering researcher, genetic engineering is catapulting arthritis treatment years ahead. Farshid Guilak, PhD, is a professor in the Department of Orthopaedic Surgery at Washington University, St. Louis, and…

Filed under:ConditionsResearch Rheum Tagged with:anti-inflammatory drugArthritisgeneticinflammationResearchRheumatic Diseaserheumatologystem cellvaccine

Refocus Your Practice with Invigorating Sessions at 2017 ACR/ARHP Annual Meeting

From the College  |  August 13, 2017

The landscape of practice management and coding methodologies continues to be challenging in the current healthcare environment, and rheumatology practices must maintain focus on managing an effective and efficient practice. Join us at the 2017 ACR/ARHP Annual Meeting, Nov. 3–8 in San Diego, and gain knowledge and understanding of best practices in an ever-changing environment…

Filed under:Career DevelopmentFrom the CollegePractice SupportProfessional Topics Tagged with:2017 ACR/ARHP Annual MeetingAuditsBillingCareerCodingCommittee on Rheumatologic Care (CORC)EducationphysicianPractice ManagementReimbursementrheumatologistrheumatologySan DiegoTraining

Novel Bone Drug Promising in Postmenopausal Osteoporosis

Reuters Staff  |  August 7, 2017

NEW YORK (Reuters Health)—The investigational drug romosozumab led to gains in hip bone mineral density (BMD) that were not seen with teriparatide in older women with osteoporosis transitioning from bisphosphonate therapy in the STRUCTURE study. Amgen’s romosozumab is a monoclonal antibody that inhibits sclerosin, a negative regulator of bone formation. In addition to stimulating bone…

Filed under:Biologics/DMARDsConditionsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:bone mineral density (BMD)Osteoporosisosteoporosis treatmentspostmenopauseromosozumab

2017 Update of Treat-to-Target Recommendations for Axial & Peripheral SpA & PsA

Michele B. Kaufman, PharmD, BCGP  |  August 7, 2017

An international task force has updated recommendations for axial and peripheral spondyloarthritis, and psoriatic arthritis, which include treat-to-target recommendations…

Filed under:Axial SpondyloarthritisConditions Tagged with:axial spondyloarthritis (SpA)Guidelinesperipheral spondyloarthritisrecommendationstarget

Oversupply of Opioids after Surgery Helps Fuel Opioid Epidemic

Ronnie Cohen  |  August 3, 2017

(Reuters Health)—More than two-thirds of surgery patients in a recent study had prescription opioids left over after they recovered from their operations, and the vast majority failed to safely store or dispose of the often misused and abused pills, researchers say. “Unused opioids that have been prescribed for pain after surgery serve as an important…

Filed under:Drug Updates Tagged with:opioid crisisopioid epidemicoverprescribingunused opioids

Refocus Your Practice with Invigorating Sessions in San Diego

From the College  |  August 2, 2017

The landscape of practice management and coding methodologies continues to be challenging in the current healthcare environment, and rheumatology practices must maintain focus on managing an effective and efficient practice. Join us at the 2017 ACR/ARHP Annual Meeting, Nov. 3–8 in San Diego, and gain knowledge and understanding of best practices in an ever-changing environment…

Filed under:Education & TrainingFrom the CollegeProfessional Topics Tagged with:2017 ACR/ARHP Annual MeetingCommittee on Rheumatologic Care (CORC)

Online Risk Calculator for Knee OA Influences Patient Risk Perception

Arthritis Care & Research  |  August 1, 2017

A new tool for assessing the risk of developing knee osteoarthritis (OA) may be useful for knee OA education. A recent study found the online risk calculator, OA Risk C, was effective in helping patients better understand their personal risk of developing the disease. It may also motivate some patients to embrace exercise-related behavior changes…

Filed under:ConditionsOsteoarthritis and Bone DisordersResearch Rheum Tagged with:Arthritis Care & ResearchkneeKnee Osteoarthritis (OA)patient educationrisk

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