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U.S. Health Agency Estimates 2015 Prescription Drug Spending Rose to $457 Billion

Reuters Staff  |  March 10, 2016

NEW YORK (Reuters)—Spending on prescription drugs is projected to have risen to $457 billion in 2015 and will likely continue to grow as a percentage of overall healthcare spending, a U.S. government health agency said on Tuesday. That is an increase of about 8% from 2014’s prescription drug spending, which is also an estimated figure,…

Filed under:Drug Updates Tagged with:Centers for Medicare & Medicaid Services (CMS)costsPrescription drugsspending

The ACR Addresses the FDA about the Safe Adoption of Biosimilars in the U.S.; Plus Tofacitinib Approved for RA & Romosozumab May Reduce Fracture Risk

Michele B. Kaufman, PharmD, BCGP  |  March 9, 2016

The ACR has continued its advocacy to ensure the safe adoption of biosimilars in the U.S., most recently addressing an FDA public hearing. Also, the FDA has approved tofacitinib for RA, and a clinical trial of romosozumab for patients with osteoporosis met its primary endpoint…

Filed under:Biologics/DMARDsDrug Updates Tagged with:American College of Rheumatology (ACR)BiosimilarsFDAFood and Drug AdministrationinfliximabromosozumabTofacitinibtofacitinib citrate

Doctor Quality Ratings May Be Influenced By Setting

Madeline Kennedy  |  March 8, 2016

(Reuters Health)—Patients give the same doctors different ratings depending on where their visit took place, according to a small U.S. study. Although doctors might act differently in an emergency department compared with a calmer office setting, researchers say the results also suggest that ratings are not a completely reliable measure of the quality of care…

Filed under:Practice SupportProfessional Topics Tagged with:Emergency Departmenthospitalpatient satisfactionpatient surveysphysician

From the Expert: Insight into the Intersection of Cancer & Autoimmunity

Richard Quinn  |  March 4, 2016

Research by Dr. Anthony Rosen, MD, and colleagues found a link between cancer and scleroderma, suggesting the immune system may edit cancer cells. In an interview with The Rheumatologist, Dr. Rosen explores the meaning of this finding and its potential…

Filed under:ConditionsSystemic Sclerosis Tagged with:CancerSclerodermaskinskin inflammation

Patients Get Mixed Reactions from Docs over Mail-Ordered Genetic Tests

Andrew M. Seaman  |  March 3, 2016

(Reuters Health)—Patients who order direct-to-consumer genetic tests report mixed experiences when they take the results to their doctors, a new study found. About a quarter of people who ordered direct-to-consumer genetic testing from such companies as 23andMe reported discussing the results with their primary care doctors. But nearly one in five were not at all…

Filed under:Practice SupportProfessional Topics Tagged with:genetic riskgenetic testpatient carePrimary Care Physicians

Tofacitinib Released from FDA REMS Requirement; Plus Biosimilars for Etanercept & Adalimumab Show Promise

Michele B. Kaufman, PharmD, BCGP  |  March 2, 2016

Tofacitinib has been released from the FDA’s risk evaluation and mitigation strategy requirement. The FDA is also reviewing a biologics license application for ABP-501, an adalimumab biosimilar. And CHS-0214, a proposed etanercept biosimilar, has met its primary endpoint at Week 24 in an ongoing 52-week study…

Filed under:Biologics/DMARDsDrug Updates Tagged with:adalimumabetanerceptFDAFood and Drug AdministrationTofacitinib

Does PTSD Increase Risk of RA for Women?

Arthritis Care & Research  |  March 1, 2016

Multiple studies have linked post-traumatic stress disorder (PTSD) to an increased risk of rheumatoid arthritis (RA), specifically in men. Using data from a 22-year cohort study, researchers were able to analyze the association between PTSD and the risk of RA in women. This large study builds on and expands previous findings by exploring whether the effects of PTSD differ for RA subtypes. As a secondary objective, researchers also examined smoking as a behavioral confounder and/or mediator in the relationship between PTSD and risk for RA…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:Arthritis Care & ResearchPost-Traumatic Stress Disorder (PTSD)Rheumatoid Arthritis (RA)SmokingWomen

Hidradenitis Suppurativa Tied to Higher Mortality

David Douglas  |  February 24, 2016

NEW YORK (Reuters Health)—Hidradenitis suppurativa (HS) is associated with a significantly increased risk of adverse cardiovascular (CV) outcomes and all-cause mortality, according to Danish researchers. HS is a chronic, inflammatory skin disease and is most common in women. It is typically diagnosed after long delays, Dr. Alexander Egeberg of the University of Copenhagen and colleagues…

Filed under:ConditionsSystemic Sclerosis Tagged with:cardiovascularCardiovascular diseaseHidradenitis suppurativaPsoriasisskinskin inflammation

Apremilast Proves Effective for PsA with Skin Involvement

Michele B. Kaufman, PharmD, BCGP  |  February 24, 2016

A recent Phase 3 clinical trial found apremilast safe and effective for treating patients with active psoriatic arthritis and skin symptoms who found conventional and biologic DMARDs ineffective…

Filed under:Biologics/DMARDsConditionsDrug UpdatesPsoriatic Arthritis Tagged with:apremilastPsoriasisPsoriatic Arthritisskin

Dermatology & Immunology: Skin Issues Can Present Challenges

Thomas R. Collins  |  February 23, 2016

SAN FRANCISCO—A 40-year-old woman shows up in the clinic with scarring alopecia, with an area of hyperpigmentation on the rim of her scalp, extending from just behind the temple to behind her ears. An examination with a dermatoscope shows hyperkeratotic follicular plugging. The case—in this example, the discoid form of cutaneous lupus erythematosus (DLE)—is one…

Filed under:ConditionsMyositisSystemic Lupus Erythematosus Tagged with:2015 ACR/ARHP Annual MeetingDermatologydermatomyositisImmunologyLupusskin

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