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Search results for: psoriasis

Biosimilars Great Debate: To Switch or Not?

Susan Bernstein  |  November 17, 2017

SAN DIEGO—Should patients with rheumatic diseases switch from a biologic to its biosimilar? At the 2017 ACR/ARHP Annual Meeting’s Great Debate, held Nov. 5, two rheumatologists argued whether to switch or stay put based on safety, efficacy and potential cost savings. First to the podium to make the case for switching, Jonathan Kay, MD, tweaked…

Filed under:Biologics/DMARDsEducation & TrainingMeeting Reports Tagged with:2017 ACR/ARHP Annual MeetingBiologicsBiosimilarsJonathan KayRheumatic DiseaseRoy Fleischmann

J&J’s Stelara Shows Promise Against Lupus in Study

Bill Berkrot  |  November 7, 2017

(Reuters)—Johnson & Johnson’s blockbuster psoriasis drug ustekinumab (Stelara) led to a significant reduction in disease activity in patients with systemic lupus compared with a placebo in a midstage clinical trial, according to data released on Nov. 4. Ustekinumab is already approved for psoriasis, psoriatic arthritis and Crohn’s disease and had third-quarter sales of $1.12 billion….

Filed under:Drug Updates Tagged with:SLEsystemic lupus erythematosus (SLE)ustekinumab

Rheumatology Drug Updates: Biosiomilar to Adalimumab Receives FDA Approval; plus Updates on Baricitinib, Tofacitinib, Bimekizumab

Mary Beth Nierengarten  |  October 17, 2017

FDA Approves Adalimumab-adbm On Aug. 29, the FDA approved Cyltezo (adalimumab-adbm), a biosimilar to Humira (adalimumab).1 Cyltezo was approved as a prefilled syringe to treat multiple chronic inflammatory diseases, including moderate to severe active RA, active psoriatic arthritis and ankylosing spondylitis, and moderate to severe plaque psoriasis. The treatment has also been approved for moderate…

Filed under:Axial SpondyloarthritisBiologics/DMARDsConditionsDrug Updates Tagged with:adalimumabAnkylosing SpondylitisApprovalsbaricitinibBimekizumabBiosimilarsdrug updateefficacyFDAHumiraplaque psoriasisPsoriasisQualityRARheumatoid arthritisrheumatologySafetyTofacitinib

Report on EU’s Experience with Biosimilar Drugs Released: Will U.S. Experience Be Similar?

Vanessa Caceres  |  October 17, 2017

As questions about biosimilar medications swirl among U.S. rheumatologists, a recently released report sheds some light on the European experience with biosimilars—and may offer some important insights for the U.S. market. The report, Biosimilars in the EU: Information Guide for Healthcare Professionals, was released in late April by the European Medicines Agency (EMA) and the…

Filed under:Biologics/DMARDsDrug Updates Tagged with:AC&Radverse eventsAmerican College of Rheumatology (ACR)BiosimilarsBiosimilars in the EUdrugefficacyEuropeEuropean UnionfindingsinterchangeabilityMedicationoutcomepatient carepricingreportRheumatic DiseaserheumatologistsrheumatologySafetyTreatment

The ACR Early Career Investigators to Host Sessions at 2017 ACR/ARHP Annual Meeting

Jeffrey Sparks, MD, MMSc  |  October 16, 2017

The ACR Early Career Investigators (ECI) Subcommittee has organized two sessions at the 2017 ACR/ARHP Annual Meeting in San Diego. These sessions are devoted to serving the needs of early career investigators including junior faculty, fellows, graduate students and post-docs. Both sessions provide unique opportunities to optimize the research landscape for early career investigators. Mentoring…

Filed under:Career DevelopmentFrom the CollegeProfessional TopicsResearch Rheum Tagged with:2017 ACR/ARHP Annual MeetingAmerican College of Rheumatology (ACR)Career developmentEducationinvestigatorsResearchrheumatologistsrheumatologyTraining

Whole-Body MRI, Ultrasound Imaging May Aid in Early Rheumatic Disease Diagnosis, Treatment

Thomas R. Collins  |  September 19, 2017

MADRID—Researchers say that whole-body MRI could yield an earlier diagnosis of spondyloarthropathy (SpA) in patients with early inflammatory joint symptoms, according to findings presented in a poster session at the Annual European Congress of Rheumatology (EULAR). The approach could lead to earlier treatment and better outcomes, they say. Investigators at the University of Leeds recruited…

Filed under:ConditionsOther Rheumatic ConditionsResearch Rheum Tagged with:Annual European Congress of RheumatologyDiagnosisdiagnostic testingEULARinflammationmagnetic resonance imagingMRIResearchRheumatic DiseaserheumatologyspondyloarthropathyTreatmentUltrasound

FDA Update: Biosiomilar to Adalimumab Receives FDA Approval

Michele B. Kaufman, PharmD, BCGP  |  September 6, 2017

The FDA has approved adalimumab-adbm, a biosimilar, to treat multiple chronic inflammatory diseases…

Filed under:Biologics/DMARDsDrug Updates Tagged with:adalimumabadalimumab-adbmbaricitinibFDAFood and Drug AdministrationRheumatoid Arthritis (RA)U.S. Food and Drug Administration

FDA Committee Recommends Tofacitinib Approval

Michele B. Kaufman, PharmD, BCGP  |  August 22, 2017

The FDA Arthritis Advisory Committee voted 10 to 1 to recommend approval of tofacitinib to treat psoriatic arthritis…

Filed under:ConditionsDrug UpdatesPsoriatic Arthritis Tagged with:BimekizumabFDAFood and Drug AdministrationPsoriasisPsoriatic ArthritisTofacitinib

What Do Diabetes, Islet Cells & Autoimmunity Have in Common?

Simon M. Helfgott, MD  |  August 15, 2017

“Man may be the captain of his fate, but he is also the victim of his blood sugar.” —Wilfrid Oakley, MB BChir, an early pioneer in diabetes care Perusing the list of the most notable medical achievements in the 20th century, a reader may conclude that the discovery of insulin should rank in a category…

Filed under:ConditionsOpinionRheuminationsSpeak Out Rheum Tagged with:AutoimmuneCharles BestdiabetesdiscoveryDr. Frederick Bantingglucoseinsulinislet cellsPathogenesispatient careTreatment

2 Biosimilars Make Their Way Toward the European Market

Michele B. Kaufman, PharmD, BCGP  |  July 17, 2017

Two biosimilar treatments, Rixathon and Imraldi, are moving closer to market release in Europe for the treatment of rheumatic and other diseases…

Filed under:Biologics/DMARDsDrug Updates Tagged with:adalimumabBiosimilarsEuropean Medicines AgencyPsoriasisrituximabRixathon

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