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Search results for: psoriatic arthritis

New Clinical Trials for Ustekinumab & Denosumab Biosimilars Begin Recruitment

Michele B. Kaufman, PharmD, BCGP  |  March 17, 2021

Clinical trials of biosimilar treatments, including a phase 1 study of SB17, which is biosimilar to ustekinumab, and two phase 3 studies investigating of SB16, which is biosimilar to denosumab, are currently recruiting.

Filed under:Biologics/DMARDsDrug Updates Tagged with:Biosimilarsclinical trialsdenosumabSB17ustekinumab

Has the Time Come for Wellness Promotion in Rheumatology?

Larry Beresford   |  March 15, 2021

Despite revolutionary advances in pharmacologic treatments for many rheumatic conditions in recent years, some patients still fail to reach a desired state of living with their disease, notes R. Swamy Venuturupalli, MD, FACR, a clinician and researcher in rheumatology, as well as the founder and director of Attune Health, a Beverly Hills, Calif.-based company that…

Filed under:ConditionsPractice Support Tagged with:DietExerciseIntegrated Careself-managmentStresswellness

The Effects of IL-17A Inhibitors on the Microbiota

Vanessa Caceres  |  February 16, 2021

The use of an interleukin (IL) 17A inhibitor resulted in gut microbial dysbiosis and features of subclinical intestinal inflammation in a subgroup of psoriatic arthritis (PsA) and spondyloarthritis (SpA) patients, according to a multidisciplinary, collaborative study across several institutions published in Arthritis & Rheumatology.1 Understanding the downstream effects of these perturbations is an important step…

Filed under:Axial SpondyloarthritisConditionsPsoriatic ArthritisResearch Rheum Tagged with:gut microbiotaMicrobiomePsoriatic Arthritissecukinumab

Study Examines Tofacitinib’s Long-Term Cardiovascular Risk & More

Michele B. Kaufman, PharmD, BCGP  |  February 8, 2021

In a post-marketing safety study, tofacitinib did not prove non-inferior to tumor necrosis factor inhibitors when evaluated for its long-term effects on heart disease, malignancies and serious infections in RA patients.

Filed under:Drug Updates Tagged with:Cardiovascular diseaseHeart DiseaseriskTofacitinib

Late-Breaking Abstract Session Spans the Realm of Drug-Related Research

Vanessa Caceres  |  January 25, 2021

In the late-breaking abstract session at ACR Convergence 2020, drug research for a variety of indications is reviewed.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2020diffuse cutaneous systemic sclerosisgiant cell arteritis (GCA)mavrilimumabtocilizumabTofacitinibVIG7734Ziritaxestat

The Science of Empathy in Rheumatology

Leonard H. Calabrese, DO  |  January 19, 2021

Rheumatology has arguably benefited like no other field from the proliferation of an increasingly effective pipeline of therapeutics. These medications have dramatically raised the bar for clinical outcomes for our patients in a way that we could not have envisioned a short generation ago. With such therapeutic progress now reaching a widening circle of rheumatic…

Filed under:ConditionsPatient Perspective Tagged with:Empathy

FDA Provides 2020 Rheumatology Drug Update

Susan Bernstein  |  December 17, 2020

Three FDA representatives discuss new drug indications, safety precautions and label changes, & an emergency program to rapidly evaluate existing immunomodulating therapies for use in COVID-19 patients.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2020FDAmeeting reportsU.S. Food and Drug Administration (FDA)

The 2020 ACR Review Course: Key Issues Rheumatologists Face

Jason Liebowitz, MD, FACR  |  December 17, 2020

The ACR Review Course featured eight talks providing a practical review of issues encountered by rheumatologists.

Filed under:ACR ConvergenceConditionsMeeting ReportsOsteoarthritis and Bone DisordersPediatric ConditionsVasculitis Tagged with:ACR Convergence 2020liver diseasemeeting reportsOsteoporosisPediatricpregnancyVasculitis

Biologics in Rheumatology: Revolution & Perspectives

Lara C. Pullen, PhD  |  December 8, 2020

A great deal of progress has been made in the treatment of rheumatic diseases—from glucocorticoid use to the advent of biologic therapies. Gerd Burmester, MD, discussed this progress and the impact of biologics in this year’s Phillip Hench, MD, Memorial Lecture.

Filed under:ACR ConvergenceBiologics/DMARDsMeeting Reports Tagged with:ACR Convergence 2020biologic drugsBiologicsBiosimilarsmeeting reports

Anti-TNF Treatment Trial Encouraging for High-Risk APS Pregnancies

Thomas R. Collins  |  November 19, 2020

Early results in a phase 2 trial are finding that adding a TNF blocker to other treatment could greatly lower the risk of serious complications during pregnancy for women who have antiphospholipid syndrome with lupus anticoagulant.

Filed under:ACR ConvergenceConditionsMeeting ReportsOther Rheumatic Conditions Tagged with:ACR Convergence 2020ACR Convergence 2020 - SLEAntiphospholipid Antibody Syndrome (APS)Hughes SyndromeLupus

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