ACR Convergence 2025| Video: Rheum for Everyone, Episode 26—Ableism

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Search results for: rituximab

FDA Issues Boxed Warning for Hydroxyurea & Neutropenia May Occur after Rituximab Treatments

Michele B. Kaufman, PharmD, BCGP  |  August 26, 2015

The FDA has issued a new boxed warning for Droxia (hydroxyurea). Also, according to a new study, RA patients receiving rituximab should be monitored for late-onset neutropenia…

Filed under:Biologics/DMARDsDrug Updates

Hepatitis Reaction with Rituximab Sparks Drug Safety Alert

M.J. Burton, MD, K.L. Winthrop, MD, MSPH, & J.W. Baddley, MD, MPH  |  January 1, 2015

The FDA modifies rituximab prescribing information to stress risk of hepatitis B virus reactivation

Filed under:Biologics/DMARDsDrug Updates Tagged with:drugFDAhepatitisrheumatologyrituximabSafetyvirus

ACR/ARHP Annual Meeting 2012: Cyclophosphamide and Rituximab Both Viable Treatment Options for ANCA-Associated Vasculitis

Mary Beth Nierengarten  |  February 1, 2013

Rituximab established as the drug of choice in patients with severe disease relapse, though cyclophosphamide may still play an important role for some patients, say rheumatologists

Filed under:ConditionsDrug UpdatesVasculitis Tagged with:ANCA-Associated VasculitiscyclophosphamiderituximabTreatment

Study: Inflammation Starts Earlier Than You Think

Samantha C. Shapiro, MD  |  December 12, 2025

A recently published study shows that inflammatory disease begins well before synovitis is seen on exam; a better understanding of what’s brewing before the storm could lead to the development of preventive therapies for RA.

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:ACPAanti-citrullinated protein antibodiesB cellsBiomarkersmultiomicsPathogenesisPreclinical Rheumatoid Arthritissystemic inflammationT-cells

The Promise of Hope in Lupus Nephritis

Colin B. Ligon, MD, MHS  |  December 9, 2025

Explore the latest lupus nephritis advances in this supplement, covering CAR-T therapy, obinutuzumab data & new diagnostic tools.

Filed under:ConditionsOpinionRheuminationsSystemic Lupus Erythematosus Tagged with:B cellsCAR-T cell therapyDubois Memorial LectureLupus nephritis supplementobinutuzumab

Lupus Nephritis: A Serious Manifestation of Systemic Lupus Erythematosus

Graciela S. Alarcón, MD, MPH, MACR  |  December 6, 2025

This review highlights some of the many abstracts on lupus nephritis research presented at ACR Convergence 2025. They demonstrate advances made on early recognition of the condition, as well as offering some hope in terms of achieving better outcomes.

Filed under:ACR ConvergenceConditionsMeeting ReportsSystemic Lupus Erythematosus Tagged with:ACR Convergence 2025ACR Convergence 2025 - LNLupus nephritis supplementresearch reviews

Reflections on B Cells in SLE & Lupus Nephritis

Ruth Jessen Hickman, MD  |  December 5, 2025

At the Dubois Memorial Lecture presented at ACR Convergence 2025, Shaun Jackson, MD, PhD, discussed the evolving understanding of the role of B cells in SLE.

Filed under:ACR ConvergenceMeeting ReportsSystemic Lupus Erythematosus Tagged with:ACR Convergence 2025ACR Convergence 2025 - LNLupusLupus nephritis supplementsystemic lupus erythematosus (SLE)

2024 ACR Guideline for the Screening, Treatment & Management of Lupus Nephritis

From the College  |  December 2, 2025

Review 28 recommendations covering proteinuria screening, biopsy indications & triple therapy regimens for lupus nephritis.

Filed under:Biologics/DMARDsClinical Criteria/GuidelinesConditionsDrug UpdatesGuidanceSystemic Lupus Erythematosus Tagged with:belimumabcalcineurin inhibitorcyclophosphamideGlucocorticoidsHydroxychloroquine (HCQ)kidney biopsyLupus nephritis supplementmycophenolate mofetilobinutuzumabProteinuriarituximabscreeningvoclosporin

Obinutuzumab Aids Standard Therapy for Lupus Nephritis

Deborah Levenson  |  December 1, 2025

Phase 3 REGENCY data: Obinutuzumab & standard therapy improve complete renal response rates in active lupus nephritis patients.

Filed under:Biologics/DMARDsConditionsDrug UpdatesResearch RheumSystemic Lupus Erythematosus Tagged with:B cell depletionLupus nephritis supplementobinutuzumabRegency trial

B Cell-Depleting Therapy in SLE & Lupus Nephritis

Katie Robinson  |  November 22, 2025

“B cells are central orchestraters of autoimmune disease by contributing to autoantibody production, antigen presentation and cytokine production,” says Georg Schett, MD, head of the Department of Medicine 3 (Rheumatology and Immunology) of the Friedrich-Alexander University Erlangen-Nürnberg, Germany. “B cells can be inhibited by monoclonal antibodies and chimeric antigen receptor (CAR) expressing cells.” Dr. Schett…

Filed under:ConditionsResearch RheumSystemic Lupus Erythematosus Tagged with:B cell depleting therapyB cell depletionCAR-T cell therapyCD19 CAR-T cell treatmentImmunologyLupus nephritis

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