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Search results for: tocilizumab

Bloody Important: Atherosclerosis & Thrombotic Disease in Rheumatic Conditions

Jason Liebowitz, MD, FACR  |  August 19, 2020

During the 2020 ACR State-of-the-Art Clinical Symposium, Zoltán Szekanecz, MD, PhD, addressed the risks of vascular disease and how to manage them in patients with rheumatic diseases.

Filed under:ConditionsEULAR/OtherMeeting Reports Tagged with:atherosclerosisEULARthrombosisvenous thromboembolism

Case Report: Diagnosing a Lupus-Flare Mimic

Nobuya Abe, MD, Yuichiro Fujieda, MD, PhD, & Tatsuya Atsumi, MD, PhD  |  August 12, 2020

The diagnosis of rheumatic diseases requires the exclusion of other systemic disorders. Infection, hematologic conditions, malignancies and some drugs may all lead to syndromes that closely mimic rheumatic diseases, which may lead to diagnostic delays. Idiopathic multicentric Castleman disease (iMCD) is a heterogeneous group of lympho­proliferative diseases (LPDs) characterized by systemic inflammatory manifestations.1,2 As with…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:Castleman's diseaseRaynaud’s phenomenon

Doctors Detail Kawasaki-Like Disease in Adult COVID-19 Patients

Carolyn Crist  |  July 17, 2020

(Reuters Health)—During the COVID-19 pandemic, an inflammatory condition similar to Kawasaki disease has been reported in children and adolescents, and now two groups of New York doctors each describe a case, one in a 36-year-old woman and one in a 45-year-old man.1 “We’re still learning how COVID-19 is affecting children and adults. The better we…

Filed under:Conditions Tagged with:coronavirusCOVID-19Kawasaki disease

Case Report: Does She Have a Fungal Infection or Autoimmune Disease?

Case Report: Does She Have a Fungal Infection or Autoimmune Disease?

Sarah Dill, MD, & Duane Pearson, MD  |  July 15, 2020

A 61-year-old Caucasian woman with a history of seropositive rheumatoid arthritis (RA) was hospitalized for a several-month history of progressively worsening left ankle pain and swelling. She had been unable to bear weight on her left leg for several days and did not notice improvement in symptoms with 20 mg of prednisone daily, which she…

Filed under:ConditionsRheumatoid Arthritis Tagged with:case reportdisseminated sporotrichosisfungalsporothrix

Case Report: Which Vasculitis Is It?

Mary Buckley, MD, & Jeffrey Dvergsten, MD  |  June 15, 2020

A 13-year-old, adopted girl of unknown ancestry with social anxiety, selective mutism and Takayasu arteritis presented for evaluation of severe, painful, gingival hyperplasia, which limited her oral intake and resulted in weight loss. The young patient was diagnosed with Takayasu arteritis at age 8, when she presented with a persistently elevated erythrocyte sedimentation rate (ESR),…

Filed under:ConditionsVasculitis Tagged with:Behçet’s diseasecase reportTakayasu arteritis (TAK)

Rheumatology Biologic Expertise Valued for COVID-19 Treatment Decisions

Catherine Kolonko  |  May 18, 2020

At the Loma Linda University Medical Center, Calif., rheumatologists play a key consulting role for COVID-19 patients who may benefit from the use of biologic treatments…

Filed under:Biologics/DMARDsDrug Updates Tagged with:BiologicscoronavirusCOVID-19cytokine storm syndromeCytokinesmacrophage activation syndrome

Sentavio / shutterstock.com

Rheumatoid Arthritis Therapy Update: What’s Changed & What’s the Same

Kimberly Retzlaff  |  May 15, 2020

SNOWMASS VILLAGE, COLO.—Current trends in rheumatoid arthritis (RA) therapy are the increased use of newer medication categories, such as Janus kinase (JAK) inhibitors (Jakinibs) and biologics, and the rising costs of treatment. Unchanged is the consistent use of methotrexate as an effective therapy. These topics and more were discussed at the ACR Winter Symposium during…

Filed under:Biologics/DMARDsConditionsRheumatoid Arthritis Tagged with:costsjanus kinase inhibitorMethotrexateWinter Rheumatology Summit

The initial physical examination was significant for a nonblanching, papular rash along the palmar aspects of the hands and digits, periungual erythema, and edema and tenderness of the proximal and distal interphalangeal joints of the hands.

Case Report: A Patient with Clinically Amyotrophic Dermatomyositis & Associated ILD & RA Overlap

Vania Lin, MD, MPH, & Leah Krull, MD  |  May 15, 2020

Clinically amyotrophic dermatomyositis (CADM), a subset of dermatomyositis (DM), is a rare autoimmune disease characterized by typical DM cutaneous findings (e.g., heliotrope rash, Gottron papules, Gottron sign) without evidence of myositis.1 The incidence of DM and CADM is approximately 9.63 per 1 million people and 2.08 per 1 million people, respectively.2 The association with development…

Filed under:ConditionsRheumatoid Arthritis Tagged with:Clinically Amyotrophic Dermatomyositis (CADM)combination therapyinterstitial lung disease (ILD)

Rheumatology in a COVID & Post-COVID World

Christopher Phillips, MD  |  May 11, 2020

Jane’s* hands and wrists had been swollen and painful for about eight weeks. Lab findings in the ambulatory consult that came to our office revealed a cyclic citrullinated peptide antibody count >250 u/mL. We all know where this story goes, including how important the early treatment window is. Our clinic reviews all consults and tries…

Filed under:Practice Support Tagged with:COVID-19Dr. Chris Phillipstelehealth

Serum Interleukin 6 Levels May Predict Presentation of IgG4-Related Disease

Lara C. Pullen, PhD  |  May 11, 2020

A retrospective study found serum interleukin 6 levels at the onset of IgG4-RD may significantly correlate with clinical inflammatory parameters and the involvement of the bile duct, liver and spleen…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:IgG4 related diseaseIgG4-RDIL-6

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