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Articles tagged with "Rheumatoid Arthritis (RA)"

Investigators Assess Infection Risk with RA Biologics

Thomas R. Collins  |  August 29, 2018

Due to a range of factors, determining the precise infection risk posed by new biologic therapies to RA patients is difficult. But progress has been made and health registries may be helpful, said Olivier Lortholary, MD, PhD, during the 2018 EULAR: Annual European Congress of Rheumatology…

TNF Inhibitors Do Not Seem to Boost Cancer-Recurrence Rates

Will Boggs, MD  |  August 15, 2018

NEW YORK (Reuters Health)—Tumor necrosis factor (TNF) inhibitors do not appear to increase cancer-recurrence rates in patients with rheumatoid arthritis (RA), according to new findings from Sweden. TNF has both tumor-promoting and cancer-protective effects, so TNF inhibitors could conceivably affect the risk for cancer recurrence. However, few studies have reported the risk for cancer relapse…

B Cell Receptor Clones May Predict RA Onset

Lara C. Pullen, PhD  |  August 15, 2018

Researchers have determined that dominant B cell receptor (BCR) clones in peripheral blood may predict the onset of clinical signs and symptoms of RA…

Effects of Obesity on Sustained Remission in Early RA

Arthritis Care & Research  |  August 6, 2018

A new study examined the independent effects of excess weight and obesity on achieving sustained remission in rheumatoid arthritis (RA) patients. Researchers found that within three years of RA diagnosis, overweight and obese patients were significantly less likely to achieve sustained remission than patients with healthy body mass indices (BMIs). Higher BMIs were also associated with persistent disease activity…

Upadacitinib Promising for RA Patients

Michele B. Kaufman, PharmD, BCGP  |  July 23, 2018

Upadacitinib proved safe and effective in RA patients who had inadequate responses to conventional disease-modifying anti-rheumatic drugs…

RISE Continues to Improve Offerings for Providers

From the College  |  July 5, 2018

ACR members are realizing what they have at their fingertips—a registry fully staffed with knowledgeable people ready to help them succeed under MIPS. This valuable resource allows members to do what they do best: Treat patients with rheumatoid arthritis (RA), which is one of the primary goals of the Rheumatology Informatics System for Effectiveness (RISE)…

Pain Links Fibromyalgia & RA

Arthritis & Rheumatology  |  June 26, 2018

Many patients with rheumatoid arthritis (RA) report pain despite excellent control of inflammation with immunotherapies. Variable degrees of coexisting fibromyalgia (FM) may explain this disparity. RA patients who have the highest 2011 ACR FM survey criteria scores appear to share neurobiologic features consistently observed in FM patients. This study is the first to provide neuroimaging evidence that RA is a mixed pain state, with many patients’ symptoms being related to the central nervous system rather than to classic inflammatory mechanisms…

FDA Approves Baricitinib for RA Patients

Michele B. Kaufman, PharmD, BCGP  |  June 25, 2018

The FDA has approved baricitinib in a 2 mg tablet dose to treat patients with moderate to severe active rheumatoid arthritis…

Disease-Modifying Antirheumatic Drugs Cut RA Risk

Reuters Staff  |  June 21, 2018

NEW YORK (Reuters Health)—Disease-modifying antirheumatic drugs (DMARDs) reduce the risk of developing rheumatoid arthritis (RA) in patients with early undifferentiated arthritis, researchers from France report. Several studies have suggested that conventional or biological DMARDs might interfere with the pathogenic process and prevent more established forms of RA, but it remains unclear whether these drugs are…

Targeted Rheumatoid Arthritis Treatment Does Not Improve Mental Health

Will Boggs MD  |  June 14, 2018

NEW YORK (Reuters Health)—Effective pharmacotherapy of rheumatoid arthritis (RA) is not associated with meaningful improvements in mental health, according to a systematic review and meta-analysis. “We were surprised by the small effect sizes for mental-health outcomes across all of the treatments included in this review, but particularly for the anti-TNF versus disease-modifying antirheumatic drug (DMARD)…

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