SAN FRANCISCO—The Kveim-Siltzbach skin test for a diagnosis of sarcoidosis was developed in 1941, then popularized in 1961. Since then, the knowledge base about the disease has not expanded much, said Kristin Highland, MD, who has dual appointments at Cleveland Clinic’s Respiratory Institute and Orthopedics and Rheumatology Institute. “We don’t know a whole lot more…
Without reliable diagnostic tests or evidence-based treatment guidelines, patient symptoms critical to diagnosing disease
Fever in rheumatology patients may present evidence of an inflammatory process
A rheumatologist voices skepticism that physicians, patients can arrive at mutually shared healthcare decisions
Test your diagnostic knowledge with this case of multiple erythematous, slightly hyperpigmented waxy papules coalescing into plaques without scale over both distal lower extremities
Two patients with psoriatic arthritis treated with TNF-alpha inhibitor therapy develop the multisystem disease
A 33-year-old woman presents with somewhat pruritic, nodular lesions worsening over the past three months in the site of a newly placed tattoo. The nodules are restricted to certain portions of the tattoo only.
Figure 2: Hematoxylin and eosin stain from punch biopsy of lesional skin demonstrated sarcoidal granulomas, inflamed. Review the case… The correct answer is D) Sarcoidosis: This patient’s first presentation of sarcoidosis consisted of skin lesions that were sarcoidal granulomas localized to a single pigment color within her tattoo (note the red pigment areas only are affected)….