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Articles tagged with "side effect"

What Patients with Lupus Want You to Know

Jacqueline Jansz, MD, with Nadera Sweiss, MD  |  August 11, 2023

During a series of interviews with patients who have systemic lupus erythematosus, issues related to medication side effects, supplement use, depression and support groups arose, as well as concerns about race and activities of daily living. The interviews gave me a better understanding of what patients with lupus wish their physicians knew. I am grateful…

Glucocorticoids May Decrease White Matter Integrity & Change Gray Matter Volume

Samantha C. Shapiro, MD  |  February 27, 2023

Van der Meulen et al. found the use of both systemic and inhaled glucocorticoids is associated with changes in several brain imaging parameters, including decreased white matter integrity and gray matter volume. Study patients also reported more depressive symptoms and tiredness than controls.

FDA Update: Romosozumab’s Uncertain Future; Plus Tocilizumab Approved for GCA

Michele B. Kaufman, PharmD, BCGP  |  June 9, 2017

Due to possible heart-related side effects, romosozumab is no longer expected to be approved this year for the treatment of osteoporosis…

FDA Drug Labeling, Approval Process Help Minimize Lawsuits Against Pharmaceutical Companies

Bruce N. Cronstein, MD  |  April 17, 2017

Like many people, I am up early and in the gym most days. Although I don’t seem to get anywhere new on the stationary bicycle or the elliptical machine, I do get to keep up with the pundits on the early morning talk shows. In contrast to the television series I binge on later in…

GI Side Effects Leading Reason for Bisphosphonate Nonadherence

Reuters Staff  |  July 6, 2016

NEW YORK (Reuters Health)—Gastrointestinal side effects are the most common reason osteoporotic women cite for nonadherence to oral bisphosphonate therapy, according to a new survey. “Our findings highlight the importance of low tolerability to nonadherence with osteoporosis therapy and underlines patients’ poor awareness and suboptimal physicians’ involvement in conveying the importance of this therapy,” Dr….

FDA Restricts Use of Systemic Fluoroquinolones Due to Side Effects & Will Review Application of Apadaz for Pain

Michele B. Kaufman, PharmD, BCGP  |  June 1, 2016

The FDA has issued new safety guidelines for systemic fluoroquinolones, restricting their use to patients with no alternative treatment options…

FDA Reviewers Question Safety of AstraZeneca’s Gout Drug

Amrutha Penumudi  |  October 23, 2015

(Reuters)—The U.S. Food and Drug Administration staff reviewers have raised concerns about kidney- and heart-related side effects noted in trials on AstraZeneca Plc’s gout treatment, especially at higher doses. FDA reviewers, in a preliminary review published on Wednesday, expressed concerns over higher death rates related to the side effects in patients who took the drug,…

NSAIDs: The Heart of the Controversy

Kurt Ullman  |  June 1, 2007

Rheumatologists on the AHA statement and how to balance NSAID risks and benefits

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