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Search results for: ibuprofen

Ibuprofen an Option for Early Pain Control after Hip Replacement

Reuters Staff  |  February 13, 2019

NEW YORK (Reuters Health)—Combining paracetamol (acetaminophen) with ibuprofen does not cut postoperative use of morphine in a clinically meaningful way relative to ibuprofen alone, in patients undergoing total hip arthroplasty (THA), results of a Danish randomized trial suggest. “Although the combined use of paracetamol and ibuprofen reduced immediate postoperative morphine consumption compared with paracetamol alone…

Filed under:AnalgesicsDrug Updates Tagged with:hiphip arthroplastyIbuprofenPainPain Managementsurgerytotal hip arthroplastytotal hip replacement

Study Examines Why Patients Exceed Recommended Doses of Ibuprofen & NSAIDs

Michele B. Kaufman, PharmD, BCGP  |  April 2, 2018

A recent study examined how often patients exceed the dosing limits of nonsteroidal anti-inflammatory drugs and identified the characteristics of the patients most likely to exceed recommended doses…

Filed under:AnalgesicsDrug Updates Tagged with:dosageNonsteroidal anti-inflammatory drugs (NSAIDs)NSAIDsPain Management

Ibuprofen More Likely to Raise BP than Naproxen or Celecoxib

Anne Harding  |  September 12, 2017

NEW YORK (Reuters Health)—Ibuprofen boosts blood pressure (BP) more than naproxen or celecoxib in patients who take non-steroidal anti-inflammatory drugs (NSAIDs) to treat arthritis, according to a new substudy from the PRECISION trial. “These drugs are different with regard to BP, and ibuprofen is the worst,” Dr. Frank Ruschitzka of University Hospital Zurich in Switzerland,…

Filed under:AnalgesicsDrug Updates Tagged with:Arthritisblood pressurecelecoxib (Elyxyb)IbuprofennaproxenNonsteroidal anti-inflammatory drugs (NSAIDs)NSAIDsPain

Sarilumab Is Effective for RA, Pregabalin Fails to Meet Study Endpoint & Ibuprofen Can Be Administered with a Patch

Michele B. Kaufman, PharmD, BCGP  |  January 13, 2016

Sarilumab is proving effective for treating RA. In a clinical trial, pregabalin did not meet its endpoint for treating post-traumatic peripheral neuropathic pain. And a 12-hour ibuprofen patch is in development…

Filed under:AnalgesicsBiologics/DMARDsDrug Updates Tagged with:Painperipheral neuropathic painpregabalinRheumatoid Arthritis (RA)sarilumab

FDA Approves Suzetrigine (VX-548), a Non-Opioid Analgesic

Michele B. Kaufman, PharmD, BCGP  |  April 29, 2025

Based on research in post-surgery patients, the FDA approved suzetrigine, a non-opioid analgesic, for the treatment moderate to severe, acute pain in adults.

Filed under:AnalgesicsDrug Updates Tagged with:acute painFDAFDA approvalsuzetrigineU.S. Food and Drug Administration (FDA)VX-548

New Study Probes Risks Related to Acetaminophen Use

Vanessa Caceres  |  April 7, 2025

A new study questions whether acetaminophen is a risk-free pain reliever for patients aged 65 and older, including those with osteoarthritis (OA). Although acetaminophen is often touted as an alternative to non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, a population-based cohort study found it carried an increased risk of peptic ulcers, bleeding and other side…

Filed under:AnalgesicsDrug UpdatesOsteoarthritis and Bone DisordersResearch Rheum Tagged with:acetaminophenResearch Reviewresearch reviewsTylenol

The 5 Ms: A Simple Framework to Care for Older Patients

Samantha C. Shapiro, MD  |  December 5, 2024

WASHINGTON, D.C.—For the first time in U.S. history, older adults are projected to outnumber children by 2034, and their care poses unique challenges to the rheumatologist.1 Normal physiologic changes of aging include but aren’t limited to falling renal function, changes in pharmacokinetics and bone density loss. At the ACR Convergence 2024 Review Course, Namrata Singh,…

Filed under:ACR ConvergenceConditionsMeeting ReportsOther Rheumatic Conditions Tagged with:ACR Convergence 2024elder care

Role Reversal: When the Doctor Becomes a Patient

Bharat Kumar, MD, MME, FACP, FAAAAI, RhMSUS  |  September 8, 2024

It was like a reverse Uno card had been thrown onto the table. My patient was now asking his rheumatologist, “Are you okay? You look like you’re in a lot of pain.” He was right. I was wincing trying to get up from my seat and limping trying to get a few steps over to…

Filed under:OpinionPatient PerspectiveRheuminations Tagged with:Rheumatic Disease Awareness MonthRheumatic Disease Awareness Month (RDAM)

Case Report: Pneumatosis Cystoides Intestinalis

Jagmohan S. Jandu, MD, MA, Sri Harsha Boppana, MD, Prahlad A. Reddy, MD, & Atigadda N. Reddy, MD, FACP, FACG, AGAF  |  November 8, 2023

Pneumatosis cystoides intestinalis (PCI) is a rare gastrointestinal pathological process defined by the presence of gas within the layers of the intestinal wall, commonly within the mucosa and submucosa of the small and large intestines.2,3 PCI has been described in the literature in association with various connective tissue diseases, including scleroderma, mixed connective tissue disease,…

Filed under:ConditionsSystemic Sclerosis Tagged with:case reportpneumatosis cystoides intestinalis (PCI)

Case Report: Migratory Polyarthritis as the Presenting Symptom of GPA

Adil Vural, MD, & Kinanah Yaseen, MD  |  May 9, 2023

Granulomatosis with polyangiitis (GPA) is a primary, necrotizing granulomatous vasculitis, involving small- to medium-sized arteries, that causes systemic disease. Almost any organ can be affected, but the most affected systems are the upper airways, lungs, kidneys, eyes and peripheral nerves. Migratory polyarthritis is reported in approximately 25% of patients with anti-neutrophil cytoplasmic antibody (ANCA) associated…

Filed under:ConditionsVasculitis Tagged with:AAV FocusRheumANCA-Associated Vasculitiscase reportGranulomatosisgranulomatosis with polyangiitismigratory polyarthritis

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