The Rheumatologist
COVID-19 News
  • Connect with us:
  • Facebook
  • Twitter
  • LinkedIn
  • YouTube
  • Feed
  • Home
  • Conditions
    • Rheumatoid Arthritis
    • SLE (Lupus)
    • Crystal Arthritis
      • Gout Resource Center
    • Spondyloarthritis
    • Osteoarthritis
    • Soft Tissue Pain
    • Scleroderma
    • Vasculitis
    • Systemic Inflammatory Syndromes
    • Guidelines
  • Resource Centers
    • Ankylosing Spondylitis Resource Center
    • Gout Resource Center
    • Rheumatoid Arthritis Resource Center
    • Systemic Lupus Erythematosus Resource Center
  • Drug Updates
    • Biologics & Biosimilars
    • DMARDs & Immunosuppressives
    • Topical Drugs
    • Analgesics
    • Safety
    • Pharma Co. News
  • Professional Topics
    • Ethics
    • Legal
    • Legislation & Advocacy
    • Career Development
      • Certification
      • Education & Training
    • Awards
    • Profiles
    • President’s Perspective
    • Rheuminations
  • Practice Management
    • Billing/Coding
    • Quality Assurance/Improvement
    • Workforce
    • Facility
    • Patient Perspective
    • Electronic Health Records
    • Apps
    • Information Technology
    • From the College
    • Multimedia
      • Audio
      • Video
  • Resources
    • Issue Archives
    • ACR Convergence
      • Systemic Lupus Erythematosus Resource Center
      • Rheumatoid Arthritis Resource Center
      • Gout Resource Center
      • Abstracts
      • Meeting Reports
      • ACR Convergence Home
    • American College of Rheumatology
    • ACR ExamRheum
    • Research Reviews
    • ACR Journals
      • Arthritis & Rheumatology
      • Arthritis Care & Research
      • ACR Open Rheumatology
    • Rheumatology Image Library
    • Treatment Guidelines
    • Rheumatology Research Foundation
    • Events
  • About Us
    • Mission/Vision
    • Meet the Authors
    • Meet the Editors
    • Contribute to The Rheumatologist
    • Subscription
    • Contact
  • Advertise
  • Search
You are here: Home / Search for "methotrexate"

Search results for: methotrexate

Pulmonary Adverse Events with Low-Dose Methotrexate

November 24, 2020 • By Arthritis & Rheumatology

In this large placebo-controlled trial, Sparks et al. examined the predictors and severity of pulmonary adverse events (AEs) in patients taking low-dose MTX. The researchers found that low-dose MTX increased the risk of pulmonary AEs, including possible pneumonitis.... [Read More]

Filed Under: Conditions, Drug Updates Tagged With: Arthritis & Rheumatology

The Great Debate: Should Jakinibs Be Used Before Biologics after Methotrexate Failure in RA?

November 9, 2020 • By Jason Liebowitz, MD

ACR CONVERGENCE 2020—In many ways, the current plethora of treatment options for rheumatoid arthritis patients represents an embarrassment of riches. However, while many therapeutics approved by the U.S. Food & Drug Administration (FDA) are available, knowing the order in which to try these medications with patients can be quite challenging. In The Great Debate, held… [Read More]

Filed Under: ACR Convergence, DMARDs & Immunosuppressives, Drug Updates, Meeting Reports, Rheumatoid Arthritis Tagged With: ACR Convergence 2020, ACR Convergence 2020 – RA

Low-Dose Methotrexate Can Cause Adverse Effects

February 19, 2020 • By Will Boggs, MD

NEW YORK (Reuters Health)—Low-dose methotrexate can be associated with gastrointestinal, pulmonary, infectious, hematologic and other adverse effects, according to an analysis of the Cardiovascular Inflammation Reduction Trial (CIRT). “Methotrexate is not a benign drug, even at dosages used for rheumatic diseases,” Daniel H. Solomon, MD, MPH of Brigham and Women’s Hospital, Boston, tells Reuters Health… [Read More]

Filed Under: DMARDs & Immunosuppressives, Drug Updates Tagged With: adverse events, Methotrexate

Pegloticase & Methotrexate Combination Therapy May Benefit Patients with Uncontrolled Gout

December 11, 2019 • By Michele B. Kaufman, PharmD, BCGP

Patients with uncontrolled gout may benefit from a combination of pegloticase and methotrexate therapy, according to a small, retrospective study…... [Read More]

Filed Under: Drug Updates Tagged With: Gout Resource Center

Case Report: RA Patient Suffers Methotrexate-Induced Cutaneous Lesions

August 16, 2019 • By Nitasha Kumar, MD

Methotrexate (MTX) remains the predominant medication used by rheumatologists to treat rheumatoid arthritis (RA). Doses of 7.5–25 mg per week with daily folic acid are generally prescribed. Despite its common use, MTX must be prescribed cautiously given the potential adverse effects when taken incorrectly or without folic acid supplementation. Cases of MTX-induced cutaneous ulceration have… [Read More]

Filed Under: Conditions, Rheumatoid Arthritis Tagged With: Methotrexate, toxicity

RA Patients May Safely Stop Methotrexate in Tofacitinib Combination Therapy

July 29, 2019 • By Michele B. Kaufman, PharmD, BCGP

RA patients who achieve low disease activity on tofacitinib and methotrexate combination therapy can safely cease methotrexate use, according to recent research…... [Read More]

Filed Under: DMARDs & Immunosuppressives, Drug Updates Tagged With: combination therapy, EULAR, Methotrexate, monotherapy, Rheumatoid Arthritis (RA), Tofacitinib

Upadacitinib + Methotrexate & Other csDMARDs in RA Patients

July 12, 2019 • By Michele B. Kaufman, PharmD, BCGP

A post-hoc analysis showed upadacitinib is safe and effective for treating RA patients when used with methotrexate or non-methotrexate csDMARDs…... [Read More]

Filed Under: DMARDs & Immunosuppressives, Drug Updates Tagged With: combination therapy, EULAR, Methotrexate, Rheumatoid Arthritis (RA), upadacitinib

Tofacitinib + Methotrexate: 2-Year Clinical, Radiographic & Safety Outcomes

June 4, 2019 • By Michele B. Kaufman, PharmD, BCGP

In a 24-month clinical trial, tofacitinib proved safe and effective in combination with methotrexate in adult patients with RA…... [Read More]

Filed Under: DMARDs & Immunosuppressives, Drug Updates Tagged With: Methotrexate, Rheumatoid Arthritis (RA), Tofacitinib

7 Insights into Methotrexate Administration, Drug Resistance & Toxicity

February 18, 2019 • By Thomas R. Collins

Li Wa / shutterstock.com

CHICAGO—Once methotrexate enters a cell through the reduced folate carrier (RFC), which thinks it is picking up folate, the drug is polyglutamated. It is this polyglutamate methotrexate that provides the actual clinical effect. These methotrexate polyglutamate “species” are added and lost over time, but it’s a slow process. What difference does it make whether a… [Read More]

Filed Under: Drug Updates, Meeting Reports Tagged With: 2018 ACR/ARHP Annual Meeting, Methotrexate

Adalimumab + Methotrexate Effective for Uveitis in JIA

October 2, 2017 • By Lara C. Pullen, PhD

Research has found that taking adalimumab plus methotrexate is effective for patients with juvenile idiopathic arthritis-associated uveitis. However, these patients may also experience an increased incidence of adverse and serious adverse events compared with those taking only methotrexate…... [Read More]

Filed Under: Conditions, Systemic Inflammatory Syndromes Tagged With: adalimumab, JIA, Juvenile Arthritis (JIA), metho­trexate, Pediatric, Pediatric Rheumatology, Uveitis

  • 1
  • 2
  • 3
  • …
  • 80
  • Next Page »

Simple Tasks

Learn more about the ACR’s public awareness campaign and how you can get involved. Help increase visibility of rheumatic diseases and decrease the number of people left untreated.

Visit the Simple Tasks site »

ACR Convergence

Don’t miss rheumatology’s premier scientific meeting for anyone involved in research or the delivery of rheumatologic care or services.

Visit the ACR Convergence site »

Meeting Abstracts

Browse and search abstracts from the ACR Convergence and ACR/ARP Annual Meetings going back to 2012.

Visit the Abstracts site »

The Rheumatologist newsmagazine reports on issues and trends in the management and treatment of rheumatic diseases. The Rheumatologist reaches 11,500 rheumatologists, internists, orthopedic surgeons, nurse practitioners, physician assistants, nurses, and other healthcare professionals who practice, research, or teach in the field of rheumatology.

About Us / Contact Us / Advertise / Privacy Policy / Terms of Use

  • Connect with us:
  • Facebook
  • Twitter
  • LinkedIn
  • YouTube
  • Feed

Copyright © 2006–2021 American College of Rheumatology. All rights reserved.

ISSN 1931-3268 (print)
ISSN 1931-3209 (online)

This site uses cookies: Find out more.