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Search results for: naproxen

Ibuprofen More Likely to Raise BP than Naproxen or Celecoxib

Anne Harding  |  September 12, 2017

NEW YORK (Reuters Health)—Ibuprofen boosts blood pressure (BP) more than naproxen or celecoxib in patients who take non-steroidal anti-inflammatory drugs (NSAIDs) to treat arthritis, according to a new substudy from the PRECISION trial. “These drugs are different with regard to BP, and ibuprofen is the worst,” Dr. Frank Ruschitzka of University Hospital Zurich in Switzerland,…

Filed under:AnalgesicsDrug Updates Tagged with:Arthritisblood pressurecelecoxib (Elyxyb)IbuprofennaproxenNonsteroidal anti-inflammatory drugs (NSAIDs)NSAIDsPain

Gout Flares & the NLRP3 Inflammasome

Katie Robinson  |  May 30, 2025

Understanding the role of NLRP3 inflammasome activation in gout flares points to potential of NLRP3 inflammasome inhibitors as new treatment option.

Filed under:ConditionsGout and Crystalline ArthritisResearch ReviewsResearch Rheum Tagged with:Arthritis & Rheumatologycase reportGoutGout Resource CenterImmunology InsightsNACHT-LRR-PYD-containing protein 3NLRP3

Editor's Pick

Weathering the Cytokine Storm: Macrophage Activation Syndrome in Adults & Children

Katie Robinson  |  December 18, 2024

Peter Nigrovic, MD, provides a practical guide to the diagnosis & treatment of macrophage activation syndrome (MAS) in children & adults.

Filed under:ConditionsOther Rheumatic ConditionsPediatric Conditions Tagged with:Arthritis & RheumatologyEditor's PickImmunologymacrophage activation syndromeMAS

Methotrexate Shows Promise for Hand Arthritis

Deborah Levenson  |  June 10, 2024

Methotrexate—an affordable, established drug for rheumatoid arthritis—may also be helpful for patients suffering from osteoarthritis (OA) of the hand, a recent study reports.1 Treatment of hand OA and inflammation with 20 mg of methotrexate for six months had a moderate, but potentially clinically meaningful, effect on reducing pain and stiffness in patients with symptomatic hand…

Filed under:ConditionsDrug UpdatesOsteoarthritis and Bone DisordersResearch ReviewsResearch Rheum Tagged with:hand osteoarthritisMethotrexatesynovitis

How to Reduce Gout Flares

Keri Losavio  |  November 12, 2023

SAN DIEGO—If patients with gout keep their serum urate (SU) levels very low with urate-lowering therapy (ULT), they have fewer flares, according to a research abstract presented at ACR Convergence 2023.

Filed under:ACR ConvergenceConditionsGout and Crystalline ArthritisMeeting ReportsResearch Rheum Tagged with:ACR Convergence 2023Gout Resource Center

Is Gout an Autoinflammatory Syndrome After All?

Jason Liebowitz, MD, FACR  |  November 29, 2022

PHILADELPHIA—The term autoinflammatory syndrome was coined by Daniel L. Kastner, MD, PhD, National Institutes of Health (NIH), Bethesda, Md., not long after he discovered that mutations in the gene MEFV, which codes for the protein pyrin, are responsible for familial Mediterranean fever (FMF).1 Early on, the term was meant to signify monogenic conditions in which…

Filed under:ACR ConvergenceConditionsGout and Crystalline ArthritisMeeting Reports Tagged with:ACR Convergence 2022ACR Convergence 2022 – GoutGout

Case Report: Sarcoidosis in Patient with History of IgG4-Related Disease

Veronica Matto, DO, Rajshri Shah, MD, Jie Ouyang, MD, PhD, Cory Perugino, DO, & Joseph J. LaConti, MD, PhD  |  September 14, 2021

Sarcoidosis and IgG4-related disease (IgG4-RD) are both immune-mediated, often multi-organ, diseases of uncertain etiology capable of presenting with diverse clinical manifestations. Many clinical features are common to both conditions, including hypergammaglobulinemia, the ability to form inflammatory masses and involvement of the lymph nodes, lacrimal glands, salivary glands, meninges and lungs. Although imaging modalities, such as…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:IgG4 related diseaseSarcoidosis

Early & Long-Term Remission of Spondyloarthritis

Jason Liebowitz, MD, FACR  |  July 16, 2021

Filip Van den Bosch, MD, described his strategies for caring for patients with SpA and the possibility of achieving disease inactivity.

Filed under:Axial SpondyloarthritisConditionsEULAR/OtherMeeting Reports Tagged with:EULARpatient carespondyloarthritis

Case Report: Does a Young Woman with Gitelman Syndrome Have Gout?

Rebecca Lindsey Weiner, DO, & Ann K. Rosenthal, MD, FACP  |  June 14, 2021

Gout is the most common type of inflammatory arthritis in adults, and it typically occurs in men over the age of 50. When gout presents in younger patients or in women, this should warrant consideration of secondary causes. We describe an unusual genetic cause of tophaceous gout in a young, premenopausal woman. Case Report In…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:case reportGitelman SyndromeGout

14 Rheumatology Treatments Make Top 50 List of Drugs That Can Cause Anaphylaxis

Michele B. Kaufman, PharmD, BCGP  |  April 15, 2021

A recent study of data from the FDA’s Adverse Event Reporting System reveals that 14 drugs commonly prescribed by rheumatologists are on the list of the top 50 drugs that can cause anaphylaxis.

Filed under:Drug Updates Tagged with:anaphylaxisFDAMedwatchU.S. Food and Drug Administration (FDA)

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