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Search results for: pregnancy

3 AC&R Study Summaries: Maternal Health & SLE, Pregnancy Outcomes & Coordinated Ophthalmic & Rheumatologic Care

Arthritis Care & Research  |  February 7, 2025

Maternal Health Insights in Patients with SLE The impact of pregnancy readiness on lupus activity, maternal mental health & pregnancy outcomes By Ceshae Harding, MD, & Megan Clowse, MD, MPH Why was this study done? Patients with systemic lupus erythematosus (SLE) who are pregnant have increased risks of risks maternal and fetal mortality, preeclampsia and…

Filed under:ConditionsResearch ReviewsResearch RheumRheumatoid ArthritisSystemic Lupus Erythematosus Tagged with:AC&RopthalmologistpregnancyReading RheumUveitis

Pregnancy Outcomes in Patients Treated with TNF Inhibitors

Michele B. Kaufman, PharmD, BCGP  |  December 18, 2023

A study found the continuation of tumor necrosis factor inhibitor (TNFi) treatment in patients with chronic rheumatic inflammatory diseases after pregnancy diagnosis was not associated with worse outcomes than those who discontinued treatment with TNFi’s.

Filed under:ACR ConvergenceBiologics/DMARDsConditionsDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2023pregnancypregnant womentumor necrosis factor inhibitor (TNFi)

New Study Probes Hydroxychloroquine Adherence During Pregnancy

Antonia Chan & Julia F. Simard, ScD  |  May 11, 2023

Hydroxychloroquine (HCQ) is nearly universally recommended for pregnant patients with systemic lupus erythematosus (SLE) to reduce lupus disease activity and adverse outcomes in pregnancy.1-3 Yet despite strong evidence supporting its benefits, HCQ appears underutilized, with several studies suggesting fewer than half of all women with lupus take this medication during pregnancy.4 How accurately these results…

Filed under:ConditionsResearch RheumSystemic Lupus Erythematosus Tagged with:adherenceHydroxychloroquine (HCQ)pregnancy

Rheumatologists Can Guide Patients During Pregnancy, Family Planning

Vanessa Caceres  |  September 27, 2022

Rheumatologists should take an active role in patients’ reproductive health, including before, during and after pregnancy. Two experts offer insights into how rheumatologists can better care for their patients during these critical times.

Filed under:Conditions Tagged with:ACR on AirACR on Air podcastpregnancypregnant women

Overcome Fear & Misinformation: Solutions for Women with Inflammatory Arthritis Considering Pregnancy

Lara C. Pullen, PhD  |  May 20, 2022

Many women with inflammatory arthritis stop filling prescriptions for medications to treat their disease during pregnancy, putting themselves at risk of disability and joint damage. Birru Talabi et al. examined why, finding that some women discontinue their medications out of fear, while others receive conflicting advice from providers or misinformation about medication safety.

Filed under:Conditions Tagged with:ACR Open Rheumatologybreastfeedingmisinformationpregnancypregnant womenreproductive healthWomen

Is Hydroxychloroquine Safe During Pregnancy?

Arthritis & Rheumatology  |  March 31, 2022

Chambers et al. found no evidence of an increased risk of major structural birth defects nor any increase in a wide range of other pregnancy outcomes attributable to prenatal exposure to hydroxychloroquine.

Filed under:Drug UpdatesResearch Rheum Tagged with:Arthritis & RheumatologyHydroxychloroquine (HCQ)pregnancypregnant womenResearch

Drug Transference in Pregnancy: RheumMadness 2022 TNFi in Cord Blood Scouting Report

University of Chicago Medicine: Lauren He, MD; & Cuoghi Edens, MD  |  March 2, 2022

A study was able to quantify the transference of tumor necrosis factor (TNF) inhibitors from mother to fetus during pregnancy. Overall, the researchers found low levels of transfer for the treatments studied.

Filed under:ConditionsDrug UpdatesResearch Rheum Tagged with:cord blooddrug transferencepregnancyRheumMadnessTNFitumor necrosis factor inhibitor (TNFi)

Pregnancy Outcomes in Patients with Psoriatic Arthritis

Arthritis & Rheumatology  |  March 1, 2022

In March A&R, Remaeus et al. reported on the results of their study, which evaluated pregnancy outcomes in relation to anti-rheumatic treatment before and during pregnancy, as a proxy of disease severity in pregnant women with psoriatic arthritis (PsA), compared with those without PsA.

Filed under:ConditionsPsoriatic ArthritisResearch Rheum Tagged with:Arthritis & RheumatologypregnancyPsAPsoriatic ArthritisResearch

TNF Inhibitors & Pregnancy: How Well Does the Treatment Guidance Work?

Michele B. Kaufman, PharmD, BCGP  |  October 21, 2021

Ghalandari et al. sought to validate the guidance outlined by EULAR for the use of anti-rheumatic drugs during pregnancy, finding that following its guidance for tumor necrosis factor inhibitors led to no or low concentrations of these agents in cord blood.

Filed under:Drug UpdatesEULAR/OtherMeeting Reports Tagged with:EULARpregnancypregnant womenTNF inhibitorsTNFiWomen

Can We Predict & Prevent Pregnancy Complications in Patients with Lupus & APS?

Thomas R. Collins  |  November 13, 2020

ACR CONVERGENCE 2020—New evidence, though derived from small numbers, suggest that treatment with the TNF-inhibitor certolizumab could help improve high-risk pregnancy outcomes in women with antiphospholipid syndrome (with or without systemic lupus erythematosus) and lupus anticoagulants, an expert said. In the Phase 2 IMPACT trial, which has already enrolled 27 women and is continuing to…

Filed under:ACR ConvergenceConditionsMeeting ReportsOther Rheumatic ConditionsSystemic Lupus Erythematosus Tagged with:ACR Convergence 2020ACR Convergence 2020 - SLE

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