One of the session’s speakers studied ACPA-positive individuals who didn’t develop RA. Do sugars and gut bacteria hold the clues? “There is a shift in cytokine expression at some point. Something changes the machinery for glycosylation in these ACPAs,” says Dr. Silverman. “Antibodies may become inflammatory because those individuals develop a leaky gut. It’s like a ticking time bomb—traced to an event in the intestines. There may be practical things we can do in food, medicines or probiotics to shift that process.”
You Might Also Like
Also By This Author
Visit the 2019 ACR/ARP Annual Meeting Online Program to learn more about the topics featured in the Basic Science sessions.
Join Us at the Annual Meeting
The 2019 ACR/ARP Annual Meeting, Nov. 8–13, in Atlanta is your gateway to global rheumatology education. View the Online Program to find out more about the opportunities for professional development and networking, and obtain firsthand access to the latest rheumatology research and clinical applications. Register now, and don’t miss out.