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How Magnetic Resonance Imaging Technology Can Aid Spondyloarthritis Diagnosis

Larry Beresford  |  Issue: August 2016  |  August 11, 2016

These images illustrate the two MRI sequences that can be used together to diagnose spondyloarthritis in the sacroiliac joint, as described by Dr. Maksymowych. The T1-weighted MRI scan of the sacroiliac joint in the semi-coronal plane (top) is a fat-sensitive sequence, so subcutaneous fat appears bright. This scan is abnormal because it shows two large areas of bright signal in the sacrum adjacent to subchondral bone characterized by a homogeneous appearance and a distinct border. A STIR scan of the sacroiliac joint in the semi-coronal plane (bottom), taken from the same patient, is a water-sensitive scan with blood vessels and cerebrospinal fluid appearing bright. This scan is abnormal because it shows areas of bright signal in the subchondral bone marrow of the sacrum, a sign of bone marrow edema. When both figures are viewed together, you can see that the area of bone marrow edema surrounds the area of fat metaplasia on the T1W scan—typical of inflammation that is resolving, but still remains active, in a patient with spondyloarthritis.

These images illustrate the two MRI sequences that can be used together to diagnose spondyloarthritis in the sacroiliac joint, as described by Dr. Maksymowych. The T1-weighted MRI scan of the sacroiliac joint in the semi-coronal plane (top) is a fat-sensitive sequence, so subcutaneous fat appears bright. This scan is abnormal because it shows two large areas of bright signal in the sacrum adjacent to subchondral bone characterized by a homogeneous appearance and a distinct border.
A STIR scan of the sacroiliac joint in the semi-coronal plane (bottom), taken from the same patient, is a water-sensitive scan with blood vessels and cerebrospinal fluid appearing bright. This scan is abnormal because it shows areas of bright signal in the subchondral bone marrow of the sacrum, a sign of bone marrow edema.
When both figures are viewed together, you can see that the area of bone marrow edema surrounds the area of fat metaplasia on the T1W scan—typical of inflammation that is resolving, but still remains active, in a patient with spondyloarthritis.

DICOM uses a large, uncompressed (5 to 10 megabyte) file format for medical images that are too large to send by email. It’s designed to allow consistent communication between scanners and the Picture Archiving and Communication System (PACS) that archives and allows retrieval of DICOM images. “DICOM viewers used by radiologists are too complicated for our purposes, and rheumatologists need something simpler. My organization, CaRE Arthritis, has developed a simplified DICOM viewer that is intuitive and doesn’t take very long to master,” he said.

Collaboration between Rheumatology & Radiology

Dr. Maksymowych strongly advocates that the rheumatologist and radiologist, who historically have occupied separate silos in healthcare, work together more closely. “The radiologist doesn’t see a lot of this particular condition, and rheumatologists, in their own silo, often don’t understand the role of MRI. They need to learn the terminology in order to have informed discussions with the radiologist,” he said. This application of MRI hasn’t been introduced into the rheumatology medical curriculum. “We don’t have trainees being exposed to the technology, and rheumatologist trainers aren’t familiar enough with it to teach it. So it becomes a vicious cycle,” he said.

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“We’re not talking about transforming rheumatologists into radiologists, but we need closer interaction and improved communication. Once the rheumatologist understands this, the pace of dialogue with the radiologist really accelerates,” he added, even to the point of requesting appropriate MRI scans for the diagnostic evaluation of spondyloarthritis.

Combining 2 MRI Sequences

Using MRI images of sacroiliac joints, Dr. Maksymowych showed the audience at CRA two different, complementary sequences of MRI scans. The T1-weighted, fat-sensitive sequence is one of the basic types of MRI scan, with fat appearing bright, as in the subcutaneous tissues. This scan provides details of the anatomy of the sacroiliac joints and is the primary type of MRI used to evaluate structural lesions such as erosion. The STIR (Short Tau Inversion Recovery) sequence is typically used to null the signal from fat and detects water, such as edema in the bone marrow, which is evidence of active inflammation and, with concomitant structural lesions, highly suggestive of axial spondyloarthritis.

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Filed under:Axial SpondyloarthritisConditionsResearch RheumTechnology Tagged with:California Rheumatology Alliance 2016ClinicalDiagnosismagnetic resonance imagingMRIoutcomepatient careResearchTechnology

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