(Reuters Health)—Among a group of New York patients with rheumatic diseases who received a SARS-CoV-2 vaccine, nearly one in six experienced disease flares after getting their shots, a new study finds.1 A survey of more than 1,100 patients who had received at least one vaccine dose revealed that 14.9% experienced flares. Among the 654 who…

Rare Disease Sheds Light on the Origins of Lupus
Patients with the rare DNASE1L3 biallelic null mutation present with childhood-onset disease that resembles lupus. This observation prompted research into how abnormalities in the enzyme DNASE1L3 are associated with lupus, with researchers finding autoantibody-mediated impairment of DNASE1L3 activity may be a common non-genetic mechanism leads to anti-dsDNA autoreactivity in SLE.
The ACR/Vasculitis Foundation Release Three New Guidelines for Treatment of Vasculitis
ATLANTA—The American College of Rheumatology (ACR), in partnership with the Vasculitis Foundation (VF), released three new guidelines for the treatment and management of systemic vasculitis. Vasculitis is a group of about 20 rare diseases that have inflammation of blood vessels in common, which can restrict blood flow and damage vital organs. The three guidelines cover…

ACR Convergence 2021: Bigger & Better Than Ever
This year’s global event offers an interactive, educational and exciting conference, with networking opportunities, insights into clinical and basic research and more.

Researchers Explore Response to COVID-19 Vaccines in the Elderly
A delayed second dose of an mRNA vaccine may provide better protection against COVID-19 in elderly patients.

Vaccine Hesitancy: Wariness Is Rare, But There’s a Wider Worry About COVID Vaccines’ Efficacy in Some Populations
Hesitancy about COVID-19 vaccination persists nationwide, although it varies among regions and sociodemographic groups.

High Cost of Specialty Drugs Demands Action
Amid rising drug costs and the growing influence of pharmacy benefit managers on patient care decisions, physicians are increasingly called upon to advocate for affordable, evidence-based treatments for their patients.

Health Canada Approves Upadacitinib to Treat Adults with PsA
Based on data from two phase 3 clinical trials, Health Canada has approved the use of upadacitinib to treat adults with active psoriatic arthritis.

New Insights into CD8+ T Cells & Lupus
A recent study demonstrated that exposure to type I interferon contributes to the pathogenesis of SLE via the metabolic rewiring of CD8+ T cells, which promotes cell death.
Advocates for Arthritis 2021 Applications Now Open
The ACR is accepting applications for this year’s Advocates for Arthritis event, which will be held virtually on Sept. 27–28. This annual event brings together patients and rheumatology professionals to advocate for our subspecialty on Capitol Hill. Applications are also open for the Advocacy 101 program, which provides advocacy training for ACR/ARP members. Apply today…
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