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An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

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Reducing Immunogenicity of Pegloticase (RECIPE) with Concomitant Use of Mycophenolate Mofetil in Patients with Refractory Gout—a Phase II Double Blind Randomized Controlled Trial

Puja Khanna, Dinesh Khanna, Gary Cutter, Jeffrey Foster, Joshua Melnick, Sara Jaafar, Stephanie Biggers, AKM Rahman, Hui-Chen Kuo, Michelle Feese and Kenneth Saag  |  December 10, 2020

Short-term concomitant use of MMF with pegloticase was generally well tolerated in this proof-of-concept study. It was associated with a statistically significant and clinically meaningful impact on the proportion of subjects achieving and maintaining a sUA ≤6 mg/dL at 24 weeks. See the abstract with bonus video discussing the validation of proposed remission and completion criteria for the treatment of gout.

The End of the Beginning: COVID-19 Vaccines & Other Conundrums

Philip Seo, MD, MHS  |  December 9, 2020

“It’s like winning Powerball.” For months, there has been a steady trickle of questions from my patients, asking for my opinion about the new vaccines being developed to prevent COVID-19. More to the point, they want to know if they should be vaccinated. After some fits and starts, I finally struck upon a pat answer…

Biologics in Rheumatology: Revolution & Perspectives

Lara C. Pullen, PhD  |  December 8, 2020

A great deal of progress has been made in the treatment of rheumatic diseases—from glucocorticoid use to the advent of biologic therapies. Gerd Burmester, MD, discussed this progress and the impact of biologics in this year’s Phillip Hench, MD, Memorial Lecture.

Medicare’s Most Favored Nation Is My Least Favorite Notion!

Angus B. Worthing, MD  |  December 8, 2020

In case you missed it, on Nov. 20, the  Centers for Medicare & Medicaid Services (CMS), a department within the U.S. Department of Health and Human Services, announced that it will overhaul the payment system for Medicare Part B (i.e., infusion) drugs on Jan. 1, 2021. The plan is called the Most Favored Nation (MFN)…

Evaluation & Management Coding Changes in the 2021 Physician Fee Schedule Final Rule

From the College  |  December 8, 2020

Implementation of rate increases for evaluation and management services and other changes bring big updates to many Current Procedural Terminology codes.

ACR Convergence graphic

Single-Cell Technologies: A Path for New Insights

Lara C. Pullen, PhD  |  December 7, 2020

This ACR Convergence session discussed how recent advances in single-cell technologies are being used in rheumatic disease research.

ACR Convergence graphic

10 Clinical Insights from Rheumatology Top Secrets & Pearls

Vanessa Caceres  |  December 7, 2020

In this ACR Convergence session, Jason R. Kolfenbach, MD, & John H. Stone, MD, MPH, shared clinical insights about rheumatic diseases.

A Year to Remember: Dr. Jinoos Yazdany Presents the 2020 Clinical Research Review

Jason Liebowitz, MD, FACR  |  December 7, 2020

During ACR Convergence 2020, Jinoos Yazdany, MD, MPH, discussed innovative research into a potential treatment for lupus, medication tapering & more. These findings may influence the treatment of rheumatic disease in the future.

ACR Convergence graphic

9 Lessons on Patient Empowerment

Thomas R. Collins  |  December 7, 2020

ACR CONVERGENCE 2020—In her ARP keynote address on Friday, Nov. 6, Empowering Patients to Make an Impact on the Future of Healthcare, Jen Horonjeff, PhD, described a study in which researchers gathered data on pain and activity level among arthritis patients. In her view, the study provided a cautionary tale. Researchers expected the study subjects…

Patients Demonstrated Good Medication Adherence While Taking Biosimilar Treatment

Michele B. Kaufman, PharmD, BCGP  |  December 7, 2020

Researchers found half of patients taking the biosimilar infliximab-dyyb (Inflectra) remained highly adherent to medication use after 12 months.

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