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The Benefits of Blood Money: OxyContin & Ethics

Philip Seo, MD, MHS  |  March 18, 2019

On Feb. 9, 2019, protesters gathered at the Guggenheim Museum in New York City to lead a march down Fifth Avenue to the Metropolitan Museum of Art.1 As a general rule, news from the world of art is not a topic discussed in these pages, but if you indulge me for just a little bit…

Applications Invited for Arthritis & Rheumatology Editor in Chief

From the College  |  March 18, 2019

The ACR Committee on Journal Publications announces the search for the position of editor in chief of Arthritis & Rheumatology. The official term of the next Arthritis & Rheumatology editorship is July 1, 2020–June 30, 2025; however, some of the duties of the new editor will begin during a transition period starting April 1, 2020….

Foundation Earns Coveted 4-Star Rating from Charity Navigator for 10th Consecutive Year

From the College  |  March 18, 2019

The Rheumatology Research Foundation’s strong financial health and commitment to accountability and transparency have earned yet another four-star rating from Charity Navigator, America’s largest independent charity evaluator. This is the 10th consecutive time the Foundation has earned this top distinction. Only 1% of charities have ever received 10 consecutive four-star evaluations, indicating the Foundation outperforms…

Calcineurin Inhibitor Pain Syndrome: A Case Report & Literature Review

Priyanka Iyer, MD, MPH  |  March 18, 2019

CHICAGO—Medications have frequently been implicated as a cause of musculoskeletal complaints, including persistent arthralgias, arthritis and myalgias.1 The list of offending agents is diverse, and the degree of symptoms is variable. In the world of transplant recipients, this list is exhaustive and includes immunosuppressive agents (cyclosporine, tacrolimus); myeloid growth factors, such as G-CSF; antibiotics (quinolones);…

New Study: Does Urate-Lowering Therapy Reduce Gout-Patient Mortality?

New Study: Does Urate-Lowering Therapy Reduce Gout-Patient Mortality?

Ruth Jessen Hickman, MD  |  March 18, 2019

Results of a recent study in Arthritis & Rheumatology fail to clarify whether urate-lowering therapies may potentially reduce mortality risk in patients with gout.1 The study also underscores the fact that many physicians are not following the ACR guideline to help their patients achieve target serum urate levels. Partly because of this, it remains unclear…

Research Suggests Th17 Cells Have Microbiota-Dependent Role in RA

Kathy Holliman  |  March 18, 2019

A growing body of research is elucidating the role of intestinal microbiota in several auto­immune diseases, including rheumatoid arthritis (RA). Research published in December 2018 Arthritis & Rheumatology increases our understanding of the “extent and nature of mucosal immune activation during preclinical arthritis.”1 The research objective, according to the report, was to “dissect intestinal mucosal immune…

The History & Future of Anti-Citrullinated Protein Antibodies (ACPAs)

Ruth Jessen Hickman, MD  |  March 18, 2019

Anti-citrullinated protein antibodies (ACPAs) are now viewed as critical diagnostic and prognostic markers for rheumatoid arthritis (RA). Research into the pathophysiology of these autoantibodies has proven to be a ripe area of investigation, opening up many promising avenues for better understanding the etiology and pathogenesis of RA. Ultimately, work utilizing these autoantibodies may also allow…

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Fellows Forum: Helpful Twitter Follows & Chats for Fellows in Training

Kanika Monga, MD  |  March 18, 2019

We spend a good portion of our day in front of screens—televisions, computers, tablets, phones and more. Social media (#SoMe) use has been on the rise, and its marriage to medicine seems inevitable. Merriam-Webster, aka America’s most trusted online dictionary, defines social media as forms of electronic communication through which users create online communities to…

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Recent Research Probes Smoking & the Risk for Autoimmune Disease

Vanessa Caceres  |  March 18, 2019

It’s no secret to any health professional, including rheumatologists, that smoking cigarettes or using other tobacco-based products is unhealthy. Yet how does smoking specifically affect rheumatic diseases, and what are some of the newest findings in this area? What role do e-cigarettes have in the smoking risk landscape? Those are the sorts of questions asked…

IgG from Patients with Autoimmune Disease Activates Neutrophils

Lara C. Pullen, PhD  |  March 18, 2019

A recent study examined the effects of immunoglobulin G (IgG) on isolated neutrophils of patients with autoimmune disease. Researchers found different autoimmune diseases have distinct patterns of IgG-mediated integrin activation and neutrophil function, which may explain disease-specific differences in vascular damage and dysfunction…

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