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Does the Metal-Fatigue Principle Apply to Elderly Bones?

Mary Beth Nierengarten  |  August 16, 2018

Can principles from engineering provide a broader understanding of how the human skeleton works and be used to help prevent a common and often consequential event for people as they age—bone fractures? Research from a team of investigators that includes orthopedic surgeons and mechanical engineers suggests that, yes, looking at how engineered materials, such as…

New Study Works Toward Better Lupus Classification Criteria

Kelly Tyrrell  |  August 16, 2018

In 1982, the ACR developed classification criteria for the identification of systemic lupus erythematosus (SLE) for use in research. The ACR updated these criteria in 1997, and in 2012, the Systemic Lupus International Collaborating Clinics (SLICC) group developed an additional set of classification criteria. In 2014, in an attempt to establish and refine even more…

The State of the Science: Annual Research Meetings Foster Collaboration & Mentorship

David Daikh, MD, PhD, & Abby Abelson, MD, FACR  |  August 16, 2018

The 11th annual Investigators’ Meeting and the Rheumatology Research Workshop, held in June in San Francisco, were by all accounts great successes. California sunshine greeted more than 120 attendees as we came together to share the latest advances and updates in rheumatology research. These annual meetings have something for every research professional, whether you work…

From Dog Clickers to Scripts—Thoughts on Learning to Teach

Philip Seo, MD, MHS  |  August 16, 2018

You can purchase a dog clicker for about $3 on Amazon. If you don’t own a dog, this is not a useful piece of information. I don’t own a dog, and the first time I heard the phrase dog clicker, I thought—I think understandably—that it was some sort of remote control. If you don’t own…

Antiphospholipid Syndrome: The Risk of Travel at High Altitudes

Antiphospholipid Syndrome: The Risk of Travel at High Altitudes

Vaneet Kaur Sandhu, MD, & Kathleen Teves, MD  |  August 16, 2018

Antiphospholipid syndrome (APS) is an autoimmune clotting disorder that may present catastrophically with multiple thromboses over a short period of time. In this article, we examine the case of a woman with undiagnosed APS whose first symptoms presented during a long-haul flight. A review of the literature on thrombosis at high altitudes and during long…

Tanezumab Promising for OA Pain; Plus, Filgotinib Investigated for Psoriatic Arthritis

Michele B. Kaufman, PharmD, BCGP  |  August 15, 2018

New research shows tanezumab may be safe and effective for patients with osteoarthritis pain…

TNF Inhibitors Do Not Seem to Boost Cancer-Recurrence Rates

Will Boggs, MD  |  August 15, 2018

NEW YORK (Reuters Health)—Tumor necrosis factor (TNF) inhibitors do not appear to increase cancer-recurrence rates in patients with rheumatoid arthritis (RA), according to new findings from Sweden. TNF has both tumor-promoting and cancer-protective effects, so TNF inhibitors could conceivably affect the risk for cancer recurrence. However, few studies have reported the risk for cancer relapse…

Lyme Arthritis Treatment Protocols Critical as Lyme Disease Spreads

Carina Stanton  |  August 15, 2018

As Lyme disease and Lyme arthritis spread to new regions in North America, physicians may ned to become aware of their signs and symptoms. Allen C. Steere, MD, says “Lyme arthritis is more complicated to treat than other manifestations of the disease.” Here are some best practices for treating Lyme arthritis…

B Cell Receptor Clones May Predict RA Onset

Lara C. Pullen, PhD  |  August 15, 2018

Researchers have determined that dominant B cell receptor (BCR) clones in peripheral blood may predict the onset of clinical signs and symptoms of RA…

Osteoporosis Drugs Tied to Lower Fracture Risk & Health Costs

Lisa Rapaport  |  August 13, 2018

(Reuters Health)—Older women with osteoporosis who consistently take a bisphosphonate may have a lower risk of fractures and lower total health costs than their counterparts who stop taking these drugs, a U.S. study suggests. Researchers examined data on 294,369 women who were at least 66 years old, insured by Medicare and prescribed osteoporosis medicines for…

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