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ACR Investigates PAMA Impact on Lab Testing

Carina Stanton  |  July 18, 2018

Rapid, accurate and convenient point-of-care lab testing for patients is one of the promises of 21st century medicine. However, reimbursement cuts enacted through the Protecting Access to Medicare Act of 2014 (PAMA) threaten access to this testing, explains Colin Edgerton, MD, FACP, RhMSUS, partner in Articularis Healthcare and chair of the ACR’s Committee on Rheumatologic…

A Comprehensive Review of NSAID Cardiovascular Toxicity

A Comprehensive Review of NSAID Cardiovascular Toxicity

Deepan S. Dalal, MD, MPH, Maureen Dubreuil, MD, MS, & David T. Felson, MD, MPH  |  July 18, 2018

Non-steroidal anti-inflammatory drugs (NSAIDs) are the most used drugs for acute and chronic pain. More than 30 billion doses of NSAIDs are consumed annually from more than 70 million prescriptions.1 Despite their common use, NSAIDs are not free of serious toxicities. In the pre-Vioxx (rofecoxib) era, gastrointestinal toxicity was the primary concern for many NSAIDs….

The Rate of Disability in Pediatric Patients with SLE

Richard Quinn  |  July 16, 2018

Recent research found 41% of pediatric patients with SLE are affected by at least mild disability, with higher pain scores correlating with increased disability. Mary Beth Son, MD, says determining how these children feel and what affects them daily is vital to “identifying targets we can hit as clinicians to improve their quality of life.”

Gout Emergency Department Visits Up

Lara C. Pullen, PhD  |  July 16, 2018

In the past nine years, visits to the emergency department by gout patients have increased by almost 27%. Researchers suggest physicians may not adequately be addressing the burden of gout and the underlying accumulation of uric acid, driving the dramatic increase in emergency department visits in the U.S…

Results from Belimumab Safety Study

Michele B. Kaufman, PharmD, BCGP  |  July 13, 2018

In a long-term extension study, belimumab proved safe, demonstrating low organ damage accrual in SLE patients treated for up to nine years…

Neutrophils & B Cells Create Unique Antibodies in Lupus Patients

Lara C. Pullen, PhD  |  July 11, 2018

NETs or LL37-DNA complexes may serve as future targets for SLE therapy. In a recent study, researchers identified a link between neutrophils and NETs, and the activation of self-reactive B cells. Their study describes a neutrophil-B cell interaction unique to lupus…

FDA Approves Combination Therapy for OA Pain, but Not Duobrii Lotion for Plaque Psoriasis

Michele B. Kaufman, PharmD, BCGP  |  July 9, 2018

The FDA has approved a combination of amlodipine and celecoxib, which may lower serum creatinine, for treating osteoarthritis pain and hypertension…

Strategies for Striking Work–Life Balance

Carina Stanton  |  July 9, 2018

Making time to advance your career and enjoy family life is no easy task. One busy rheumatologist, educator and mom shares her strategies for success…

Serum Bone Markers CTX, PINP Not Linked with Hip Fracture Risk in Osteoporosis

Anne Harding  |  July 7, 2018

NEW YORK (Reuters Health)—Levels of two bone markers currently recommended for evaluating postmenopausal women with osteoporosis have no association with hip fracture risk, according to a new study using Women’s Health Initiative data. “At least in these postmenopausal women, it was not a useful endeavor to check bone turnover markers to predict hip-fracture risk. That…

Anticonvulsants Unhelpful for Low Back Pain

Marilynn Larkin  |  July 7, 2018

NEW YORK (Reuters Health)—Solid evidence suggests that anticonvulsants provide no benefit for low back or lumbar radicular pain and a high risk of harm, researchers say. “We started the study because these drugs were increasingly being used for low back pain and radiating leg pain, without the support of strong evidence of effectiveness,” principal investigator…

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