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Research Rheum

How to Diagnose Antisynthetase Syndrome

How to Diagnose Antisynthetase Syndrome

Quretul Quresh, MD, & Stephen Lindsey, MD  |  March 17, 2017

Antisynthetase syndrome (AS) is strongly associated with the presence of antibodies to aminoacyl-transfer RNA (tRNA) synthetases (ARSs) that are implicated in the pathogenesis of myositis and interstitial lung disease (ILD). Antibodies against eight antisynthetases have been identified and are detected in 16–26% of patients with idiopathic inflammatory myopathies (IIM).1 Serum assays for five of these…

Rheumatology Research Foundation Reaches $60 Million Journey to Cure Goal

From the College  |  March 17, 2017

The Rheumatology Research Foundation is pleased to announce the overwhelming success of the Journey to Cure campaign. With a goal of raising $60 million, this five-year campaign was created to directly invest in the future of rheumatology by supporting training opportunities and funding innovative research. The campaign surpassed its goal, with a grand total of…

Spinal Underwear May Relieve Lower Back Pain

Lara C. Pullen, PhD  |  March 14, 2017

A recent study in nurses and healthcare professionals examined the efficacy of a novel ergonomic aid for managing low back pain. After a three-month trial, researchers found that the aid, Spinal Underwear, reduced low back pain, suggesting that musculoskeletal symptoms may be influenced by posture and somatization…

RISE Is Ready for MIPS

From the College  |  February 16, 2017

Implementation of the Medicare Access and Chip Reauthorization Act of 2015 (MACRA) began Jan. 1. What does this mean for rheumatologists? It means you must pick the measures by which you will be evaluated and the pace at which you will begin reporting in the Merit-Based Incentive Payment System or participating in an Advanced Alternative…

Rheumatology Drug Updates: Efficacy & Safety of Guselkumab, Plus FX006 for Knee OA

Kelly April Tyrrell  |  February 16, 2017

Guselkumab Improves Active Psoriatic Arthritis New research has revealed that patients with active psoriatic arthritis (PsA) and ≥3% body area of plaque psoriasis benefit from treatment with a human monoclonal antibody known as guselkumab (GUS). GUS is specific for the p19 subunit of interleukin 23 (IL-23). Patients in the Phase 2 clinical trial experienced significant…

Can Genetic Information Change the Clinical Care of Rheumatology Patients?

Mary Beth Nierengarten  |  February 15, 2017

WASHINGTON, D.C.—Calling it an extremely challenging topic, Peter K. Gregersen, MD, professor and head, Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institute, Manhasset, N.Y., said the current role of genetics in clinical practice is less about how to use genetic information to care for patients and more about how providers and patients…

Rheumatology Research Abstracts Highlight Treatment for Hand OA, Risk of Depression in Lupus and More

Mary Beth Nierengarten  |  February 15, 2017

WASHINGTON, D.C.—What do treating hand osteoarthritis (OA) in the primary care setting, high financial strain and risk of depression in patients with lupus, prolonged sitting and cardiovascular disease, and sex-specific treatment after total hip arthroplasty have in common? They were all topics presented during a session titled ARHP I: Exemplary Abstracts at the 2016 ACR/ARHP…

Rheumatology Research Clears Paths to Improved Arthritis Patient Care, Long-Term Health

Susan Bernstein  |  February 15, 2017

WASHINGTON, D.C.—Rheumatology researchers look for next-generation treatments, healthy interventions, and genetic and microbial clues to disease pathogenesis and therapy response, according to new studies presented at a Nov. 15, 2016, press conference at the 2016 ACR/ARHP Annual Meeting. OA & Physical Function How do you know when a patient with knee osteoarthritis (OA) has the…

Potential New Maintenance Therapies for Vasculitides Revealed

Thomas R. Collins  |  February 15, 2017

WASHINGTON, D.C.—New insights into maintenance therapy for patients with vasculitides were covered by several speakers at the 2016 ACR/ARHP Annual Meeting abstract session titled, Vasculitis I: Novel Approaches to Therapy. Expert Hubert de Boysson, MD, MSc, of the Internal Medicine Department at Caen University Hospital in France, led discussion on new therapies for patients with…

When Interstitial Lung Disease and Connective Tissue Disorder Intersect in Rheumatology Patients

Larry Beresford  |  February 15, 2017

SAN FRANCISCO—Interstitial lung disease (ILD) represents a heterogeneous group of disorders characterized by inflammation or fibrosis of the lungs. The disorders are also associated with a spectrum of connective tissue diseases (CTDs). ILD is a common manifestation of CTDs, such as scleroderma, poly-/dermatomyositis and rheumatoid arthritis—and is a leading cause of morbidity and mortality in…

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