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Search results for: Biologics

Infliximab Use Not Tied to Malignancy in Pediatric IBD

David Douglas  |  March 6, 2017

NEW YORK (Reuters Health)—Immunosuppressive therapy with infliximab (Remicade) for inflammatory bowel disease (IBD) in pediatric patients is not associated with increased risk of malignancy or hemophagocytic lymphohistiocytosis (HLH), according to a Janssen study. Dr. Jeffrey S. Hyams, who worked on the study, calls the finding “reassuring.” He adds in an email to Reuters Health, “our…

Filed under:Biologics/DMARDsDrug Updates Tagged with:hemophagocytic lymphohistiocytosisHLHIBDinflammatory bowel diseaseinfliximab

A New Administration Brings Updated ACR Policy Positions

Mary Beth Nierengarten  |  March 1, 2017

The ACR continues to broaden its advocacy efforts on issues critical to rheumatology, as described in updates to its 2017 health policy statements. Along with continuing to advocate for access to care and treatments, enhancements to rheumatology research and training the next generation of rheumatologists, the 2017 health policy statements address a number of new…

Filed under:Legislation & AdvocacyPractice SupportProfessional Topics Tagged with:Biosimilarshealth policyHealthcare ReformMACRA implementation

ACR Puts Forward Principles on Patient Access to Care

Mary Beth Nierengarten  |  March 1, 2017

As the 115th Congress and the Trump administration consider potential reforms to the healthcare system, including actions related to the Affordable Care Act (ACA), physicians around the country remain vitally concerned about the need to preserve and improve access to care for their patients. To that end, the ACR continues to lobby for policies that…

Filed under:Legislation & AdvocacyPractice SupportProfessional Topics Tagged with:Access to carechronic arthritishealthcare coveragehealthcare provisionsongoing careposition statementrheumatic diseases

ACR Releases New Position Statements on Site of Service & Compounding

Mary Beth Nierengarten  |  March 1, 2017

Patient Safety & Site of Service for Biologics Although emphasizing its strong support for the use of biologic agents as necessary treatments for rheumatic diseases, the ACR Board of Directors continues to be concerned about the safe delivery of these agents, given the potential for associated adverse events and infusion reactions. In a position statement…

Filed under:Biologics/DMARDsLegislation & Advocacy Tagged with:biologic infusionsdrug compoundingposition statementquinacrine

FDA Considers Tocilizumab for GCA & Piclidenoson Enters Phase 3 Trial for RA, Psoriasis

Michele B. Kaufman, PharmD, BCGP  |  February 27, 2017

The FDA is considering a supplemental biologics license application for tocilizumab to treat giant cell arteritis…

Filed under:Biologics/DMARDsDrug Updates Tagged with:FDAFood and Drug AdministrationGCAgiant cell arteritis (GCA)piclidenosontocilizumab

Physician’s Choice: Factors That Influence First- & Second-Line Biologic Therapy in RA Patients

Michele B. Kaufman, PharmD, BCGP  |  February 20, 2017

In patients with RA, age and higher rates of comorbidity are influential in selecting and changing treatments…

Filed under:Biologics/DMARDsDrug Updates Tagged with:abataceptbiologic drugsBiologicsRheumatoid Arthritis (RA)TNF inhibitorstocilizumab

Switch to Biosimilar Infliximab for IBD Slashes Drug Costs

Reuters Staff  |  February 17, 2017

NEW YORK—Inflammatory bowel disease (IBD) patients can be safely switched from originator infliximab to biosimilar infliximab using a managed-switching program, U.K. research shows. “Thus far, there does not appear to be any significant difference between the two infliximab products in terms of drug persistence, side effects, adverse reactions, disease activity, or blood tests, but ongoing…

Filed under:Biologics/DMARDsDrug Updates Tagged with:BiosimilarsCT-P13drug costsIBDinfliximab

ACR Urges CMMI to Test Transparently: Coalition offers principles to guide CMS’s care innovation efforts

Susan Bernstein  |  February 16, 2017

The Center for Medicare and Medicaid Innovation (CMMI), which develops concepts for healthcare payment and service delivery, must be transparent and engaged with all stakeholders as it tests new models, according to a coalition of 30 associations. On Feb. 10, the Healthcare Leaders for Accountable Innovation in Medicare Coalition, which includes the ACR, released six…

Filed under:Legislation & AdvocacyProfessional Topics Tagged with:Center for Medicare and Medicaid Innovation (CMMI)CMMIguideline principlesHealthcare Leaders for Accountable Innovation in Medicare CoalitionMACRAMedicare Access and CHIP Reauthorization Act of 2015Quality Payment Program

Biosimilars to Raise Unique Questions

Vanessa Caceres  |  February 16, 2017

Rheumatologists are accustomed to educating patients about medications, but biologic medications—and now biosimilars—require some additional time and discussion. “Biologics are inherently more complex [than other medications], and there are multiple issues to consider before initiating treatment,” says K. “Kwas” Huston, MD, The Center for Rheumatic Disease, Kansas City, Mo. The first FDA-approved biosimilar to become…

Filed under:Biologics/DMARDs Tagged with:BiologicsBiosimilarsFDAInflectraRemicade

Can Genetic Information Change the Clinical Care of Rheumatology Patients?

Mary Beth Nierengarten  |  February 15, 2017

WASHINGTON, D.C.—Calling it an extremely challenging topic, Peter K. Gregersen, MD, professor and head, Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institute, Manhasset, N.Y., said the current role of genetics in clinical practice is less about how to use genetic information to care for patients and more about how providers and patients…

Filed under:Meeting ReportsPractice SupportResearch Rheum Tagged with:2016 ACR/ARHP Annual Meetingclinical careDiagnosisgeneticsoutcomepatient careResearchRheumatic Diseaserheumatologistrheumatology

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