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Search results for: Tofacitinib

Myositis Management: Clinical Trials Provide New Insights into Treatment Options

Jason Liebowitz, MD, FACR  |  May 24, 2021

Advancements in the treatment of myositis are on their way, according to Hector Chenoy, PhD, FRCP, who outlined the latest clinical trials during the 2021 ACR State-of-the-Art Clinical Symposium.

Filed under:ConditionsMeeting ReportsMyositis Tagged with:ACR State-of-the-Art Clinical Symposiumjakinibmyositis

Gut Feeling: A Comprehensive Look at the Pathogenesis, Management & Treatment of Inflammatory Bowel Disease

Jason Liebowitz, MD, FACR  |  May 24, 2021

Patients with autoimmune diseases, such as spondyloarthritis, are at risk of developing inflammatory bowel disease. Here are considerations for its management and treatment.

Filed under:ConditionsMeeting Reports Tagged with:ACR State-of-the-Art Clinical SymposiumIBDinflammatory bowel disease (IBD)

ACR Leads AMA Resolution on Payer Financial Incentives to Patients to Switch Treatment

From the College  |  May 22, 2021

Spurred by a recent Cigna policy, the ACR will lead a resolution to oppose insurance companies providing financial incentives for patients to switch treatments. Several specialties are cosponsoring the resolution for a special meeting of the AMA House of Delegates in June.

Filed under:InsuranceLegislation & Advocacy Tagged with:AMA House of Delegates (HOD)insurance

Case Report: A Mycobacterium kansasii Infection

Kayleigh A. Sullivan, MD, MA, MPH, Nicole Orzechowski, DO, & Elizabeth A. Talbot, MD  |  May 13, 2021

A 61-year-old white woman presented to our rheumatology clinic in New England to establish care in early June 2018, following a move from Texas. She reported a medical history of inflammatory bowel disease, uveitis and sero­negative inflammatory arthritis, which was difficult to control and required the use of multiple medications. At her initial visit, she…

Filed under:Conditions Tagged with:case reportInfectionMycobacterium kansasiinontuberculous mycobacterium (NTM)

Cigna Offers Patients Financial Incentive to Switch Treatments

From the College  |  April 16, 2021

The ACR has sent a letter to Cigna expressing opposition to the initiative, which jeopardizes patients’ health, interferes with medical decision making, undermines the doctor-patient relationship and may disproportionately affect patients of lower socioeconomic status.

Filed under:Drug UpdatesInsuranceLegislation & Advocacy Tagged with:insurancenon-medical switching

Cytokine Targets & Treatment Developments for Psoriatic Arthritis & Spondyloarthritis

Carina Stanton  |  March 15, 2021

ACR CONVERGENCE 2020—In recent years, a pathophysiological role for the interleukin (IL) 17/IL-23 axis in the development of psoriasis, enthesitis and inflammatory arthritis has been investigated in both rodent and human models. Clinical trials have demonstrated differential benefits for skin disease and joint disease in patients with psoriatic arthritis, axial spondyloarthritis (axSpA) and ankylosing spondylitis…

Filed under:Axial SpondyloarthritisConditionsPsoriatic Arthritis Tagged with:ACR Convergence 2020Ankylosing SpondylitisIL-17/IL-23 CytokineJanus Kinase Inhibitorspsoriatic arthritis

Upadacitnib for RA: Researchers Compared Upadacitinib with Placebo & Adalimumab in Patients with RA & an Inadequate Response to Methotrexate

Vanessa Caceres  |  March 9, 2021

In phase 3 clinical trial, upadacitnib proved superior to placebo and adalimumab in improving the signs and symptoms of RA in patients on stable background methotrexate.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2020ACR Convergence 2020 – RAadalimumabjakinibupadacitinib

Late-Breaking Abstract Session Spans the Realm of Drug-Related Research

Vanessa Caceres  |  January 25, 2021

In the late-breaking abstract session at ACR Convergence 2020, drug research for a variety of indications is reviewed.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2020diffuse cutaneous systemic sclerosisgiant cell arteritis (GCA)mavrilimumabtocilizumabTofacitinibVIG7734Ziritaxestat

ACR Convergence 2020

Interfering with Interferon: Experts Discuss IFN Signaling & IFN Inhibition Treatment Possibilities

Mary Beth Nierengarten  |  January 25, 2021

NIH investigators describe key features and genetic causes of Mendelian interferonopathies, & treatment approaches that may indicate the efficacy of IFN inhibition.

Filed under:ACR ConvergenceConditionsMeeting Reports Tagged with:ACR Convergence 2020interferonJAK inhibitorsjakinibsignaling

Case Report: A Non-Tuberculous Mycobacterial Infection

Bradley Bohman, MD, & Jawad Bilal, MBBS  |  January 20, 2021

Tumor necrosis factor-α inhibitors (TNFi’s) have emerged as an integral part of therapeutic strategies for several rheumatic diseases. TNF-α is a pro-inflammatory cytokine implicated in the pathogenesis of rheumatoid arthritis (RA), seronegative spondyloarthropathies and inflammatory bowel disease (IBD). It also plays a central role in the immune response to mycobacterial infection.  Many biologic agents, particularly…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:bacteriacase reportInfectiontumor necrosis factor inhibitor (TNFi)

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