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Search results for: Tofacitinib

The RISE Registry Delivers Practice-Based Evidence to Rheumatologists

Nancy A. Baker, ScD, MPH, OT; Margarita Fallena, MD; Tracy Johansson, MS; Janell Martin, CAE; Kaleb Michaud, PhD; Cynthia S. Crowson, PhD; Dina L. Jones, PT, PhD  |  April 15, 2019

The advent of quality-based healthcare, such as the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA), requires rheumatology professionals to demonstrate their practice is based on interventions supported by the best available evidence and that their practice, in turn, provides quality care. These requirements have increased the need for methods to measure and quantify…

Filed under:Quality Assurance/ImprovementResearch Rheum Tagged with:practice-based researchQualified Clinical Data Registries (QCDRs)Rheumatology Informatics System for Effectiveness (RISE) Registry

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Rheumatology Drugs at a Glance, Part 1: Psoriatic Arthritis

Mary Choy, PharmD, BCGP, FASHP  |  April 15, 2019

Over the past few years, biosimilars and other new drugs have been introduced to treat rheumatic illnesses. Some of the conditions we treat have numerous drug options, others have few or only off-label options. This series, Rheumatology Drugs at a Glance, provides streamlined information on the administration of biologic, biosimilar and other medications used to…

Filed under:ConditionsDrug UpdatesPsoriatic Arthritis Tagged with:abataceptadalimumabapremilastbrodalumabCertolizumab PegoletanerceptGolimumabinfliximabixekizumabPsoriatic ArthritisRheumatic Drugs at a GlancesecukinumabTofacitinibtreatment guidelinesustekinumab

The RISE Registry: A Powerful Collaboration Tool for Clinicians & Researchers

Nancy A. Baker, SCD, MPH, OT; Margarita Fallena, MD; Tracy Johansson, MS; Janell Martin, CAE; Kaleb Michaud, PhD; Cynthia S. Crowson, PhD; Dina L. Jones, PT, PhD  |  March 21, 2019

Practice-based evidence, like that in the RISE registry, can be used to describe trends in patient care, look at comparative effectiveness of interventions and much more.

Filed under:Practice SupportResearch Rheum Tagged with:electronic health records (EHRs)practice-based evidencepractice-based researchRheumatology Informatics System for Effectiveness (RISE) RegistryRISE registry

The Latest on Vaccinations, Leprosy & Lyme Disease

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—Keith Winthrop, MD, MPH, professor of public health and preventive medicine at the Oregon Health & Science University School of Medicine, Portland, Ore., began the vaccination session at the 2018 ACR/ARHP Annual Meeting with a review of vaccination timing and targets. He presented a clinically relevant snapshot of the vaccines rheumatologists should consider and emphasized…

Filed under:ConditionsMeeting Reports Tagged with:2018 ACR/ARHP Annual MeetingleprosyLyme Diseasevaccination

The Latest on Epigenetics in Immune-Mediated Disease

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—Because the epigenome has been implicated in a variety of rheumatic conditions, a Basic Research Conference was convened on Epigenetics in Immune-Mediated Disease in conjunction with the 2018 ACR/ARHP Annual Meeting. Melanie Ehrlich, PhD, professor of human genetics and genomics at Tulane University School of Medicine, New Orleans, opened the conference. She has a long…

Filed under:ConditionsMeeting Reports Tagged with:2018 ACR/ARHP Annual Meetingepigeneticsepigenome

Safety Risk with Higher Dose Tofacitnib

Michele B. Kaufman, PharmD, BCGP  |  March 6, 2019

According to the FDA, an ongoing safety trial found higher dose tofacitinib increased the risks of pulmonary embolism and death in RA patients…

Filed under:Drug Updates Tagged with:cardiovasculardeathDrug SafetyFood and Drug Administrationpulmonary embolismsafety warningTofacitinibU.S. Food and Drug Administration (FDA)

FDA Advisory Committee Votes in Favor of Romosozumab Approval

Michele B. Kaufman, PharmD, BCGP  |  January 30, 2019

An FDA advisory committee voted 18-1 in favor of approving romosozumab to treat postmenopausal women with osteoporosis.

Filed under:ConditionsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:boneFDAOsteoporosisromosozumabU.S. Food and Drug Administration (FDA)

Moderate Liver Enzyme Elevation Found in Patients With & Without Hepatic Steatosis

Carina Stanton  |  January 2, 2019

Limited data are available on liver enzyme elevation in patients with RA, PsA and psoriasis being treated with tofacitinib and methotrexate. But early study findings are shedding light on the nature and risks of liver enzyme levels in these patients…

Filed under:Conditions Tagged with:fatty liver diseasehepatic steatosisliverliver enzyme levelsTofacitinib

New Guideline for the Treatment of Psoriatic Arthritis

Arthritis & Rheumatology  |  December 18, 2018

ACR guidelines include recommendations for the management of patients with particular conditions or diseases. Guidelines are developed using a systematic process and are based on available evidence and the clinical experience and expertise of rheumatologists and other interested stakeholders. In the January issue of Arthritis & Rheumatology, Arthritis Care & Research and the Journal of…

Filed under:ConditionsPsoriatic ArthritisResearch Rheum Tagged with:American College of Rheumatology (ACR)Arthritis & RheumatologyguidelinePsoriatic ArthritisResearch

psoriatic arthritis hand photo

New PsA Guideline Released

Kathy Holliman  |  December 17, 2018

The ACR & the National Psoriasis Foundation (NPF) have published a joint Guideline for the Treatment of Psoriatic Arthritis (PsA). The guideline will serve as an aid to practitioners managing active PsA in patients.

Filed under:Clinical Criteria/GuidelinesConditionsPsoriatic Arthritis Tagged with:first-line use of a TNFiJoint Guideline for the Treatment of Psoriatic Arthritis (PsA)National Psoriasis Foundation (NPF)oral small molecule (OSM) drugsPsA Resource CenterPsoriatic ArthritisTNFi biologic

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