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Search results for: fever

2019 EULAR/ACR SLE Classification Criteria Offer Improved Sensitivity & Specificity

Susan Bernstein  |  November 6, 2019

The new EULAR/ACR classification criteria for SLE offer improved sensitivity and specificity, as well as more accurately reflect the current tests used to clinically diagnose SLE. A positive ANA test is obligatory…

Filed under:ConditionsResearch RheumSystemic Lupus Erythematosus Tagged with:criteriaResearchsystemic lupus erythematosus (SLE)

Insight into the Characteristics of Orphan Autoinflammatory Disorders

Carina Stanton  |  November 4, 2019

New research seeking to describe the characteristics of undefined, systemic autoinflammatory diseases may have identified distinct subgroups, including pericarditis and intellectual impairment…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:Familial Mediterranean feverOrphan Autoinflammatory DisordersSystemic inflammatory disease

Case Report: A Patient Develops Scleroderma Renal Crisis

Adria Madera-Acosta, MD, Teresa Sosenko, MD, & Diana Girnita, MD, PhD  |  October 18, 2019

Scleroderma renal crisis (SRC) is a life-threatening complication of systemic sclerosis. SRC occurs in 2–15% of patients with diffuse sclerosis and usually within the first five years from the time of diagnosis. Risk factors for SRC include, but are not limited to, early diagnosis, corticosteroid or cyclosporine use, and the presence of anti-RNA polymerase III…

Filed under:ConditionsSystemic Sclerosis Tagged with:case reportdiffuse systemic sclerosisScleroderma Renal Crisis

How to Improve Rheumatologist-Hospitalist Communication & Access

Larry Beresford  |  October 18, 2019

The traditional model for subspecialist consultations on hospitalized patients by outpatient-based rheumatologists may seem straightforward. Hospitalists (the inpatient specialists who now manage most in-hospital medical care in the majority of U.S. hospitals) typically call upon the rheumatologist’s expertise for joint swelling and a rash or fever of unknown origin, says Lianne Gensler, MD, of the…

Filed under:Practice SupportProfessional Topics Tagged with:Consultationhospitalists

Case Report: A Patient on Apremilast Develops Streptococcus Salivarius

Stephanie Kydd Dondero, DO, & Barry Waters, MD  |  October 18, 2019

Apremilast was first marketed in March 2014 for the treatment of adults with psoriatic arthritis (PsA). An immuno­modulating drug, which is a small molecule inhibitor of phosphodiesterase 4 (PDE4) specific for cyclic adenosine mono­phosphate (cAMP), apremilast is administered orally. By inhibiting PDE4, intracellular cAMP levels are increased. Although the exact mechanism of action is not…

Filed under:Conditions Tagged with:apremilastcase reportimmunosuppressive drugsStreptococcus salivarius

Imagining a Life Free from the Pain of Ankylosing Spondylitis

Lara C. Pullen, PhD  |  September 30, 2019

Dan Reynolds, the lead singer of the Grammy award-winning band Imagine Dragons, has partnered with Novartis to increase awareness of ankylosing spondylitis.

Filed under:Axial SpondyloarthritisConditionsPsoriatic Arthritis Tagged with:Ankylosing SpondylitisMonster Pain in the ASNovartisplaque psoriasisPsoriatic Arthritissecukinumab

Case Report: Diagnosing, Treating Hepatitis B-Linked Polyarteritis Nodosa

Naveen Raj, DO, & Lisa Duncan, MD   |  September 17, 2019

Hepatitis B virus (HBV) associated polyarteritis nodosa (PAN) is an increasingly rare vasculitis in developed countries due to advances in HBV vaccination and antiviral therapy. However, the condition does persist, and rheumatologists should consider it when evaluating vasculitis cases. Below, we discuss a case that illustrates the varied clinical presentations PAN can encompass. A high…

Filed under:ConditionsVasculitis Tagged with:case reporthepatitis Bpolyarteritis nodosa

Case Report: Does a Rapid-Onset Neck Mass Have Rheumatic Origins?

Tej Bhavsar, MD, & Nancy Joste, MD  |  September 17, 2019

A 54-year-old African American man arrived at the emergency department with the acute onset of a tender mass on the left side of his neck. It had been getting progressively larger for the preceding two days. History & Examination His history included chronic right hip osteoarthritis with two surgeries performed five years prior. At his…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:AmyloidosisCancercase report

AJPhoto / Science Source

Tips for Diagnosing Metabolic Myopathies

Ruth Jessen Hickman, MD  |  September 17, 2019

When evaluating patients with possible myopathic symptoms, rheumatologists must consider a rare, but important, group of inherited disorders: the metabolic myopathies. However, their diagnosis often remains a challenge. Early recognition of these primary metabolic myopathies is essential to help prevent disease morbidity and mortality from rhabdomyolysis. Here, we focus on the metabolic myopathies that present…

Filed under:Conditions Tagged with:creatinine kinesegenetic diseasegenetic disordersMetabolic Myopathiesrhabdomyolysis

Rituximab-Induced Serum Sickness Is More Frequent in Autoimmune Diseases

Lara C. Pullen, PhD  |  September 2, 2019

Recent research into rituximab-induced serum sickness (RISS) reinforces the understanding that patients generally recover quickly. However, the study also found patients with autoimmune disease, especially SLE, had a significantly higher risk for developing RISS than patients using rituximab to treat hematological malignancy…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:rituximabrituximab-induced serum sicknessSerum Sickness

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