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Old Drug, New Interest: COVID-19 Spurs Hydroxychloroquine Supply Concerns for Rheumatic Disease Patients

Susan Bernstein  |  March 27, 2020

After a study investigated if hydroxycholoroquine (HCQ) benefits COVID-19 patients, the drug—used to treat SLE and RA patients—began running out in pharmacies around the U.S. ACR leaders have asked the FDA to increase monitoring of the HCQ supply…

Filed under:Drug Updates Tagged with:coronavirusCOVID-19Drug shortageHCQHydroxychloroquine (HCQ)

COVID-19 Pandemic Leads Big Drugmakers to Hit Pause on Clinical Trials

Reuters Staff  |  March 25, 2020

(Reuters)—U.S. drugmakers Eli Lilly and Co. and Bristol Myers Squibb said they are delaying the start of new clinical trials in part to free up doctors and healthcare facilities to deal with the surge in patients infected with the new coronavirus. Lilly and Bristol are the biggest drugmakers yet to announce clinical trial delays in…

Filed under:Drug UpdatesResearch Rheum Tagged with:clinical trialscoronavirusCOVID-19drugmakersResearch

Roche Gets FDA Nod for Trial to Test Arthritis Drug on COVID-19 Patients

Reuters Staff  |  March 25, 2020

March 23 (Reuters)—Roche Holding AG said on Monday it has received the U.S. Food and Drug Administration‘s clearance to test its rheumatoid arthritis treatment on patients hospitalized with severe pneumonia caused by the coronavirus. The company said it was beginning a late-stage study to test the drug in what would be the first well-controlled study…

Filed under:Drug Updates Tagged with:coronavirusCOVID-19FDAtocilizumabU.S. Food and Drug Administration (FDA)

Sarilumab Investigated to Treat COVID-19

Michele B. Kaufman, PharmD, BCGP  |  March 23, 2020

A study investigating sarilumab’s effects on patients with COVID-19 has begun in New York. The treatment blocks IL-6, which may play a role in the respiratory distress caused by the virus…

Filed under:Drug Updates Tagged with:clinical trialsCOVID-19sarilumab

Enemy at the Gates: The Emerging Threat of COVID-19

Philip Seo, MD, MHS  |  March 23, 2020

On Dec. 30, 2019, an ophthalmologist named Li Wenliang notified his colleagues about an illness that was reminiscent of severe acute respiratory syndrome (SARS) in a city in the Hubei province of China called Wuhan. As an ophthalmologist, this was not directly relevant to his practice; he merely wanted to warn colleagues that they might…

Filed under:ConditionsOpinionProfessional TopicsRheuminationsSpeak Out Rheum Tagged with:COVID-19Philip SeoRheuminationsSeo

Axial Spondyloarthritis & Exercise: Should axSpA Patients Exercise?

Mike Fillon  |  March 23, 2020

Two experts weigh in on whether & how axial spondyloarthritis patients should exercise…

Filed under:Axial SpondyloarthritisConditions Tagged with:2019 ACR/ARP Annual Meetingaxial spondyloarthritis (SpA)ExerciseExercise/physical therapy

New Options Emerge for Treating Macrophage Activation Syndrome

Mike Fillon  |  March 19, 2020

ATLANTA—Macrophage activation syndrome (MAS), a subset of hemophagocytic lymphohistiocytosis (HLH) disease, can be a fatal result of rheumatic disease. But there’s good news: New therapeutic options for refractory MAS targeting individual cytokines are emerging. At the 2019 ACR/ARP Annual Meeting, possible therapeutic options were presented during a pediatric-focused clinical and translational research track, Therapeutic Approaches…

Filed under:Conditions Tagged with:2019 ACR/ARP Annual MeetingIL-1macrophage activation syndrome

Key Studies Highlighted: 2 Industry Veterans Discuss Their Favorite Annual Meeting Abstracts

Mike Fillon  |  March 19, 2020

ATLANTA—With more than 3,000 abstracts from 103 countries presented at the 2019 ACR/ARP Annual Meeting in November, it was impossible for attendees to view them all. However, two ACR/ARP veterans—Arthur Kavanaugh, MD, from the University of California, San Diego, and John Cush, MD, from UT Southwestern Medical School, Dallas—chose to tackle the nearly impossible task and…

Filed under:Axial SpondyloarthritisConditions Tagged with:2019 ACR/ARP Annual MeetingBiologicsburnouthyperuricemiamachine learningmacrophage activation syndromepregnancy

The Doctor Will See You Now: Legal & Regulatory Reforms Expand Telemedicine

Steven M. Harris, Esq.  |  March 17, 2020

In this time of COVID-19, you may be considering ways to deliver routine rheumatologic care via some form of telemedicine. Here are some of the legal considerations.

Filed under:Legal UpdatesProfessional Topics Tagged with:COVID-19telehealthtelemedicine

Don’t Forget the Host: COVID-19 Cytokine Storm

Randy Q. Cron, MD, PhD, & W. Winn Chatham, MD  |  March 16, 2020

The new coronavirus outbreak, COVID-19, reminds us how we have struggled to keep ahead of mutating pathogens through the ages.

Filed under:Conditions Tagged with:COVID-19

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