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Does MRI Differentiate Osteoarthritis and Meniscal Tear in Knee Pain?

Kelly April Tyrrell  |  December 19, 2017

When a young patient arrives at a clinic complaining of knee pain with clicking or popping, a meniscal tear is often the culprit. “In young [people], there’s a pretty classic presentation of meniscal tear, with clicking and other mechanical symptoms, because the tear rubs up against different tissues,” says Jeffrey Katz, MD, MSc, a rheumatologist…

Filed under:ConditionsResearch Rheum Tagged with:ACR Journal ReviewAmerican College of Rheumatology (ACR)Arthritis Care & ResearchDiagnosisjointknee painmeniscal tearmeniscusOsteoarthritispatient careResearchrheumatologistrheumatologyRisk Factorsstudy

Long-Term Benefits, Risks of Biologic Disease-Modifying Anti-Rheumatic Drugs in Patients with RA

Nan Yang, PharmD, & Kurt Oelke, MD, on behalf of the ARHP Practice Committee  |  December 19, 2017

Two decades have passed since the first biologic disease-modifying anti-rheumatic drug (bDMARD) was approved. Studies on the long-term use of biologics in different disease states, such as for cardiovascular disease (CVD) and malignancy, as well as for knee/hip replacement, reveal some encouraging news. In clinical trials, bDMARDs have been shown to increase the risk of…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:Association of Rheumatology Professionals (ARP)bDMARDbenefitsbiologic disease-modifying antirheumatic drugsCardiovascular diseaseClinicalhipkneeoutcomepatient carereplacementResearchRheumatoid arthritisrheumatologistrheumatologyriskstudytherapy

Rheumatology Drug Updates: Hip Fracture Rates After Bisphosphonate Drug Holidays, Plus More on Golimumab, Ustekinumab

Michele B. Kaufman, PharmD, BCGP  |  December 19, 2017

Bisphosphonate Drug Holidays Drug holidays are common for patients on bisphosphonate therapy. Often, these breaks in treatment are related to known U.S. Food and Drug Administration (FDA) warnings and drug class adverse effects. Currently, data on fracture risk related to drug holidays are limited. In recent research highlighted at the 2017 ACR/ARHP Annual Meeting ,…

Filed under:Axial SpondyloarthritisConditionsDrug UpdatesOsteoarthritis and Bone DisordersResearch Rheum Tagged with:Ankylosing SpondylitisApprovalsbisphosphonatesbone lossdrug therapyFDAFracturesGolimumabhipOsteoporosisosteoporosis treatmentsoutcomepatient careplaque psoriasisResearchrheumatologyriskSafetyustekinumabwarning

Fellows’ Forum Case Report: Progressive Weakness and Debilitation with Skin Rash

Usman T. Malik, MBBS  |  December 19, 2017

The Presentation A pale, quiet woman—her mother—wheeled the girl into my clinic. It was a blistering Florida day, and the girl was shivering. She glanced up at me when I said hello and asked her name. “Hi,” she said, giving me a broad smile. Her smile was the only broad thing about her. Her elbows…

Filed under:ConditionsMyositisOther Rheumatic Conditions Tagged with:amyopathyAutoimmune diseaseClinicaldermatomyositisDiagnosisfellowFellowsFellows Foruminflammatory myopathymuscle weaknessoutcomepatient carepolymyopathyRheumatic DiseaserheumatologistrheumatologysymptomTestTreatment

Inside Cambodia’s Struggles with Poverty, Dearth of Trained Rheumatologists

Elizabeth Hofheinz, MPH, Med  |  December 18, 2017

It’s one thing for a developing country to lack physicians due to a scarcity of training. It’s quite another for such a vacuum to exist because the physicians were executed. In Cambodia in the 1970s, genocide perpetrated by the Khmer Rouge spared few of the educated class. If they were spared, chances were they lost…

Filed under:ConditionsProfiles Tagged with:CambodiacostsDiagnosisDr. Victoria SeligmandrugEducationgenocideHealth Volunteers OverseasKhmer RougeLupuspatient carephysicianpovertyrheumatologistrheumatologySihanouk Hospital Center of HopeSLETrainingVolunteer

Cardiovascular Disease Rate Differs Between SLE Patients of Different Races, Ethnicities

Kurt Ullman  |  December 18, 2017

A recent epidemiologic study of patients with systemic lupus erythematosus (SLE) investigated racial and ethnic differences in the risk for cardiovascular disease (CVD). Among SLE patients enrolled in Medicaid, the risk for myocardial infarction (MI) was lower in Hispanics and Asians compared with whites, and the risk of stroke was higher in blacks and Hispanics…

Filed under:ConditionsResearch RheumSystemic Lupus Erythematosus Tagged with:ACR JournalAmerican College of Rheumatology (ACR)Cardiovascular diseasecomorbiditiesethnicitiesheartHispanicLupusMyocardial infarctionoutcomepatient careraceResearchrheumatologistrheumatologyriskstrokestudySystemic lupus erythematosus

Is Rheumatoid Arthritis Preventable?

Kurt Ullman  |  December 18, 2017

Is rheumatoid arthritis (RA) preventable? Results of a newly published study suggest that personalized medicine approaches may result in health behavior that may reduce RA risk. “We have gotten to the point where we’ve identified some modifiable behaviors that affect rheumatoid arthritis risk,” says Jeffrey A. Sparks, MD, MMSc, assistant professor of medicine in the…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:ACR Journal ReviewAmerican College of Rheumatology (ACR)behaviorClinicalpatient carePersonalized medicinePersonalized Risk Estimator for RApreventionRAResearchRheumatoid arthritisrheumatologistrheumatologyriskstudyTreatment

Strong Statistical Association Found Between Trauma and Lupus

Elizabeth Hofheinz, MPH, MEd  |  December 18, 2017

They say the body remembers what the mind wants to forget. For those who have experienced trauma, not only does the body remember, in some cases it works on making things worse. Such is the situation with trauma and lupus, says a new study published in Arthritis & Rheumatology in October. The study, titled, “Association…

Filed under:ConditionsResearch RheumSystemic Lupus Erythematosus Tagged with:ACR Journal ReviewArthritis & RheumatologyflareImmune SysteminflammationLupusNurses' Health Studyposttraumatic stress disorderResearchrheumatologyriskStressstudySystemic lupus erythematosusWomen

Laurent/Yakou / Science Source

How to Recognize, Diagnose Periodic Fever Syndromes in Adults

Rick Brasington, MD  |  December 18, 2017

A number of autoinflammatory syndromes that result from genetic mutations have been described recently. The vast majority occur in children. However, three periodic fever syndromes are important for rheumatologists who treat adults to know about. The goal of this review is to provide a concise description of each condition, and to help the clinician understand…

Filed under:ConditionsOther Rheumatic ConditionsPediatric Conditions Tagged with:adult Still's DiseasearthralgiasArthritisASDautoinflammatoryClinicalDiagnosisFamilial Mediterranean feverfevergenetic mutationoutcomepatient carePediatricreceptor-associated periodic syndromerheumatologistrheumatologyTRAPSTreatment

Fellows’ Forum Case Report: Necrotizing Autoimmune Myopathy

Shivani Garg, MD, Suzana Alex John, MD, & Frehiywot Ayele, MD  |  December 18, 2017

Necrotizing autoimmune myopathy (NAM) is a relatively recently discovered subgroup of inflammatory myopathies. NAM is characterized by predominant muscle fiber necrosis and regeneration with little or no inflammation.1 One subgroup of NAM is 3-hydroxy-3-methylglutaryl-CoA reductase antibody (HMGCR Ab)-related immune-mediated necrotizing myopathy (IMNM), which occurs (rarely) after statin exposure, with a rough incidence of two per…

Filed under:Other Rheumatic ConditionsResearch Rheum Tagged with:Autoimmunecase reportClinicalDiagnosisfellowFellowsFellows ForumHMGCR Ab-related IMNMimmune-mediated necrotizing myopathyinflammatory myopathymorbiditymortalitymuscle weaknessmyalgianecrotizingpatient careResearchrespiratoryrheumatologistrheumatologyStatinstatin-associated myopathy

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