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Search results for: idiopathic inflammatory myositis

CAR-T Cells: Are We Closer to Drug-Free Remission Than We Think?

Samantha C. Shapiro, MD  |  July 8, 2024

Most Sunday mornings, I make myself an exceptional cup of pour-over coffee and sit down on my deck with the latest issue of the New England Journal of Medicine. I check out the image of the week. I read the case report with pen in hand, racing to diagnose the patient before the authors spill…

Filed under:Drug UpdatesGuidanceResearch ReviewsResearch Rheum Tagged with:CAR-T cell therapyRemission

CAR-T Cell Therapy in Autoimmune Disease: The Next Frontier

Jason Liebowitz, MD, FACR  |  July 2, 2024

Chimeric antigen receptor (CAR) T cell therapy has the potential to fundamentally shift the treatment of autoimmune disease. During his presentation at EULAR 2024, Georg Schett, MD, provided an overview of this treatment process and described the promising findings of the latest research.

Filed under:Biologics/DMARDsConditionsEULAR/OtherMeeting ReportsSystemic Lupus Erythematosus Tagged with:CAR-T cell therapychimeric antigen receptor T (CAR-T) cellsEULAR 2024ImmunologyResearchSLE Resource Centersystemic lupus erythematosus (SLE)

A World of Difference: Updates from the Global Rheumatology Summit

Jason Liebowitz, MD, FACR  |  January 20, 2023

The second annual Global Rheumatology Summit focused on climate change, conflict and migration, as well as other global issues in rheumatology.

Filed under:ACR ConvergenceConditionsMeeting ReportsMyositis Tagged with:ACR Convergence 2022Global Rheumatology Summitidiopathic inflammatory myositisMentorshippatient accessWorkforce

Options for Refractory Gout, ILD & More

Ruth Jessen Hickman, MD  |  November 18, 2022

PHILADELPHIA—At the first Plenary Session of ACR Convergence 2022, on Saturday, Nov. 12, speakers shared key research findings on the efficacy and safety of methotrexate as a co-therapy with pegloticase in refractory gout, the effectiveness of rituximab and cyclophosphamide in connective tissue disease associated-interstitial lung disease and the value of remote education for primary care…

Filed under:ConditionsGout and Crystalline ArthritisOther Rheumatic ConditionsSystemic Sclerosis Tagged with:ACR Convergence 2022ACR Convergence 2022 – Gout

Fellow’s Forum Case Report: When Pulmonary Symptoms Point to Rheumatic Disease

Naina Rastalsky, MD  |  September 1, 2013

A 48-year-old man with diffuse arthralgias and acute respiratory failure is diagnosed with antisynthetase syndrome

Filed under:ConditionsSystemic Sclerosis Tagged with:Antisynthetase SyndromearthralgiasPulmonaryrespiratoryRheumatic Disease

AC&R Study Summary: Standardizing Treatment for Moderately Severe JDM

By Matthew A. Sherman, MD, MHSc, & Stacey E. Tarvin, MD, MS  |  November 10, 2024

Why was this study done? Juvenile dermatomyositis (JDM) is the most common type of idiopathic inflammatory myopathy in childhood, and most patients have a chronic disease course requiring prolonged administration of systemic glucocorticoids and immunosuppressive agents. The initial management for patients with moderately severe JDM is relatively standardized, typically including methotrexate and systemic glucocorticoids with…

Filed under:Biologics/DMARDsConditionsDrug UpdatesGuidelinesMyositisResearch ReviewsResearch Rheum Tagged with:juvenile dermatomyositisReading Rheum

Editor's Pick

The ACR and CHEST Release 2 New ILD Guidelines

Ruth Jessen Hickman, MD  |  July 9, 2024

Clinicians should not rely on glucocorticoids as a first-line treatment of SARD-ILD in patients with systemic sclerosis, according to a strong recommendation in a new ILD treatment guideline from the ACR and CHEST. The guideline is one of two addressing the screening, monitoring and treatment of patients with interstitial lung disease (ILD) secondary to systemic autoimmune rheumatic diseases (SARDs).

Filed under:ConditionsGuidanceGuidelinesOther Rheumatic ConditionsRheumatoid ArthritisSjögren’s DiseaseSystemic Sclerosis Tagged with:Editor's PickILDInterstitial Lung Diseaseinterstitial lung disease (ILD)

ACR Image Competition 2023 Results, Part 5

David Mecham, DO  |  April 10, 2024

For the 2023 Image Competition, the ACR sought images representing a diverse range of patients with idiopathic inflammatory myopathies (IIMs) or IIM mimics. Pneumomediastinum & Ulcerative Cutaneous Dermatomyositis These images depict a 22-year-old woman with a recent diagnosis of anti-melanoma differentiation-associated gene 5 (MDA-5) antibody dermatomyositis who sought evaluation of worsening skin rashes and pleuritic…

Filed under:ConditionsMyositis Tagged with:anti-MDA-5 antibody dermatomyositisdermatomyositisimage case reportImage Competition

ACR Image Competition 2023 Results, Part 4

Doron Rimar, MD  |  March 7, 2024

For the 2023 Image Competition, the ACR sought images representing a diverse range of patients with idiopathic inflammatory myopathies (IIMs) or IIM mimics. Unilateral Heliotrope Rash in Anti-MDA-5 Antibody Dermatomyositis These images depict a 36-year-old patient with arthralgias, dyspnea and a unilateral heliotrope rash (image A). A unilateral heliotrope rash is a distinctive, but rare,…

Filed under:ConditionsMyositis Tagged with:anti-MDA-5 antibody dermatomyositisdermatomyositisimage case reportImage Competitionrash

ACR Image Competition 2023 Results, Part 3—People’s Choice Winner

Rajat Ranka, MD  |  February 9, 2024

For the 2023 Image Competition, the ACR sought images representing a diverse range of patients with idiopathic inflammatory myopathies (IIMs) or IIM mimics. Chronic Facial Ulcers in Anti-Melanoma-Differentiation-Associated Gene 5 (MDA-5) Antibody Amyopathic Dermatomyositis These images depict a 27-year-old patient who developed erythematous violaceous lesions over his upper chest, face and scalp over six months….

Filed under:ConditionsMyositis Tagged with:amyopathic dermatomyositisdermatomyositisimage case reportImage Competition

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