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Search results for: knee pain

Tanezumab for OA Pain

Michele B. Kaufman, PharmD, BCGP  |  February 21, 2019

In a recent study, tanezumab proved more effective than placebo in treating patients with moderate to severe pain caused by hip or knee osteoarthritis…

Filed under:AnalgesicsDrug Updates

How to Proceed When Kids Present with Joint Pain but Normal Exams

Susan Bernstein  |  January 17, 2019

CHICAGO—When it comes to correctly diagnosing joint pain in children, “things take time,” said Michael L. Miller, MD, quoting Danish physicist and poet Piet Hein. Children with pain but normal physical examinations may need to return to the clinic for repeat evaluation over several months. “I often tell parents that laboratory tests may help in…

Filed under:ConditionsMeeting Reports Tagged with:2018 ACR/ARHP Annual MeetingarthralgiasChildrenJoint PainPediatrics

Arthralgias in Children: What to Do When Kids Present with Joint Pain

Susan Bernstein  |  December 17, 2018

The evaluation of a child with arthralgia who has a normal physical examination provides a challenge to rheumatologists. Here are some insights into assessing and treating children with musculoskeletal pain syndromes…

Filed under:ConditionsPediatric Conditions Tagged with:arthralgiasChildrenPainPediatric

Emerging Treatments for OA: New Therapies Target Joint Pain, Not Just Structural Damage

Susan Bernstein  |  November 28, 2018

CHICAGO—Are effective treatments for osteoarthritis (OA) on the horizon? In Emerging Treatments for Osteoarthritis at the 2018 ACR/ARHP Annual Meeting, experts discussed potential therapies to address OA structural progression, pain and inflammation. With an aging population and rising obesity rates, “we can expect the prevalence of osteoarthritis will only increase,” said Anne-Marie Malfait, MD, PhD,…

Filed under:American College of RheumatologyConditionsMeeting ReportsOsteoarthritis and Bone Disorders Tagged with:2018 ACR/ARHP Annual MeetingPain

Biomarkers for Knee OA

Gretchen Henkel  |  November 18, 2018

Knee osteoarthritis (OA) accounts for more than 80% of OA disease burden and has doubled in prevalence in the mid-20th century in the U.S. when compared with people who lived during early industrial era (1800s to early 1900s).1 Currently, the diagnostic and treatment armamentaria are limited. Disease progression is measured by joint space narrowing on…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:BiomarkersFNIH Biomarkers Consortium

Is More Better? Weight Loss Analysis in Older Patients with Knee OA

Arthritis Care & Research  |  November 5, 2018

Obesity is a modifiable risk factor for many patients with knee osteoarthritis (OA), and the National Institutes of Health recommend an initial weight loss goal of 10%. But how does losing more weight affect knee OA patients? In a new study, researchers compared the outcomes of knee OA patients who lost more and less than the recommended 10% of their baseline weight, finding significant improvement in health-related quality of life and reduction in pain for patients who lost twice what’s recommended…

Filed under:ConditionsOsteoarthritis and Bone DisordersResearch Rheum Tagged with:Arthritis Care & ResearchkneeKnee Osteoarthritis (OA)Obesityweight loss

Central Sensitization to Pain May Not Predict Long-Term Outcomes after Carpal Tunnel Release Surgery

Lara C. Pullen, PhD  |  October 29, 2018

Pain sensitization, such as that experienced by patients with carpal tunnel syndrome (CTS), has been associated with poorer clinical outcomes after surgery. New research has found that, although pain sensitization in CTS patients correlates with preoperative symptom severity, CTS symptoms did not have a persistent effect on functional outcomes after surgery…

Filed under:Conditions Tagged with:carpal tunnel releaseCarpal Tunnel SyndromePainpain sensitizationsurgery

New Research Shows Knee Osteoarthritis Prevalence Is Rising

Mary Beth Nierengarten  |  September 20, 2018

Studies highlighting the large numbers of people affected by knee osteoarthritis (OA) point to what clinicians who treat knee OA have been seeing for the past few decades: a substantial increase in the prevalence of knee OA in the U.S. and globally. Roughly 250 million people are affected by knee OA worldwide, and about 14…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:body mass index (BMI)knee osteoarthritisphysical activity

Tanezumab Promising for OA Pain; Plus, Filgotinib Investigated for Psoriatic Arthritis

Michele B. Kaufman, PharmD, BCGP  |  August 15, 2018

New research shows tanezumab may be safe and effective for patients with osteoarthritis pain…

Filed under:Drug Updates Tagged with:filgotinibhipkneeKnee Osteoarthritis (OA)osteoarthritis (OA)PainPsoriatic Arthritistanezumab

Don’t Rule Out Placebos for Osteoarthritis Pain Control

Thomas R. Collins  |  July 19, 2018

CHICAGO—The placebo effect in treating pain in osteoarthritis (OA) should not be discounted, an expert said at the ACR State-of-the-Art Clinical Sym­posium in April. It’s especially important to accept the effect as real considering that trials of pain therapies in OA generate such high placebo effects (typically at least 40%) and that OA treatment options,…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:2018 State of the Art Clinical Symposiumalternative therapiesplacebo

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