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Search results for: osteoporosis

Undetected Fractures Linked to Back Pain in Older Men

Shereen Lehman  |  September 22, 2017

(Reuters Health)—About three in five older men with tiny spinal fractures related to osteoporosis reported new or worsening back pain in a new study. Only about one-quarter of new vertebral fractures are diagnosed by a doctor, the study team writes in their September 7 online report in Journal of Bone and Mineral Research, though the…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:Back painFracturesOsteoporosisundetected fracturesvertebral fracture

Abatacept Plus Prednisone Therapy Studied for Treating Giant Cell Arteritis

Linda Childers  |  September 17, 2017

A recent study, conducted by the Vasculitis Clinical Research Consortium and funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), examined whether the addition of abatacept, a drug that affects T cell activation, to standard prednisone treatment could reduce the risk of relapse in patients with giant cell arteritis (GCA).1 Although…

Filed under:ConditionsResearch RheumVasculitis Tagged with:abataceptACR Journal ReviewAmerican College of Rheumatology (ACR)Giant Cell ArteritisGlucocorticoidspatient careprednisonerelapseResearchrheumatologyriskSteroidT celltherapyTreatmentVasculitis

Alendronate Decreases Hip Fracture Risk in Older Patients Using Oral Prednisolone

Lara C. Pullen, PhD  |  August 21, 2017

New research found that older patients on prednisolone who are also treated with alendronate experience a significantly lower risk of hip fracture. Alendronate use was also associated with a lower risk of death…

Filed under:Conditions Tagged with:alendronateelderlyFractureship fracturehip fracture riskprednisolone

Switching from Bisphosphonates to Teriparatide May Improve BMD in Women with RA

Scott Baltic  |  August 19, 2017

NEW YORK (Reuters Health)—Switching women with rheumatoid arthritis (RA) from oral bisphosphonates to teriparatide increases bone mineral density (BMD) and trabecular bone score, according to a new report. Researchers in Japan conducted an 18-month observational study of more than 175 women with RA (mean age: 66) who remained on oral bisphosphonates, switched to denosumab (DMAb),…

Filed under:ConditionsOsteoarthritis and Bone DisordersRheumatoid Arthritis Tagged with:bisphosphonatesbone mineral density (BMD)Osteoporosisosteoporosis treatmentsRheumatoid Arthritis (RA)teriparatideteriparatide treatment for osteoporosisWomen

Rheumatology Drug Updates: Opana ER Painkiller Pulled from U.S. Market; Upadacitinib to Treat RA, and More

Michele B. Kaufman, PharmD, BCGP  |  August 13, 2017

Opana ER Pulled from U.S. Market Last month, the U.S. Food and Drug Administration (FDA) asked Endo Pharmaceuticals to remove oxymorphone hydrochloride extended release (Opana ER) from the U.S. market due to public health consequences related to abuse. The agency has concerns that the risks presented by the treatment do not outweigh its benefits.1 On…

Filed under:Drug UpdatesResearch Rheum Tagged with:abataceptabuseAddictionApprovalsClinicalDrugsEndo PharmaceuticalsFDAMedicationOpana ERopioidoxymorphone hydrochloride extended releasepainkillerResearchresultsSafetytopical diclofenac sodiumtrialupadacitinib

University of Nebraska Division of Rheumatology and Immunology Makes Education, Clinical Research Top Priorities

Gretchen Henkel  |  August 13, 2017

When it was created in 1982, the Division of Rheumatology and Immunology at the University of Nebraska Medical Center comprised one-and-a-half rheumatologists: its founder, Lynell W. Klassen, MD, MACR, and Gerald Moore, MD, who later received formal training at the NIH and now serves as senior associate dean for academic affairs. Thirty-five years later, the…

Filed under:ConditionsEducation & TrainingMyositisProfilesResearch Rheum Tagged with:biobanksClinical researchEducationgout and systemic lupus erythematosusImmunologymyositisRheumatoid arthritisrheumatologySclerodermaTrainingtrialsUniversity of Nebraska

Rheumatology Drug Updates: Uncertain Future for Romosozumab, Plus FDA Approves Tocilizumab for GCA

Michele B. Kaufman, PharmD, BCGP  |  July 20, 2017

Romosozumab’s Future Is Uncertain Romosozumab, which has the possible U.S. brand name Evenity, is awaiting approval from the FDA.1 The treatment is an investigational, injectable biologic for treating osteoporosis. It increases bone formation and bone density, reducing a patient’s risk of fractures. The manufacturer no longer expects the FDA to approve the drug this year…

Filed under:ConditionsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:amputationApprovalsbonecanagliflozindrugFDAFracturesGiant Cell ArteritisMedicationMyocardial infarctionNSAIDOsteoporosisrheumatologyriskromosozumabSafetytocilizumabTreatment

News Updates for Diclofenac Sodium, Denosumab & Sarilumab

Michele B. Kaufman, PharmD, BCGP  |  June 20, 2017

In drug news, a generic 2% diclofenac sodium solution is now available, denosumab is promising to treat osteoporosis, and the FDA has approved sarilumab to treat adults with RA…

Filed under:Biologics/DMARDsConditionsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:denosumabdiclofenac sodiumFDAFood and Drug Administrationgeneric drugsKnee Osteoarthritis (OA)OsteoporosisRheumatoid Arthritis (RA)sarilumab

International Task Force Recommends Intra-articular Hyaluronic Acid for Knee OA

Kathy Holliman  |  June 15, 2017

An international task force convened by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) recommends systematic repeated intra-articular hyaluronic acid (HA) injections as second-line treatment for patients with knee osteoarthritis (OA). This is the first time a group of experts has made this recommendation, which is directed toward treatment of…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:ClinicalEuropean Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritisguidelinehyaluronic acidjointkneeOAOsteoarthritisoutcomepatient carerecommendationrheumatologistrheumatologyTreatment

Rheumatologists Treating Patients with HIV Face Treatment, Diagnostic Challenges

Rheumatologists Treating Patients with HIV Face Treatment, Diagnostic Challenges

Ruth Jessen Hickman, MD  |  June 15, 2017

Rheumatologists treating HIV patients in 2017 must think through many important factors as this population ages. As we continue to learn, rheumatologists must consider important drug–drug interactions, relatively uncommon rheumatological presentations of HIV, as well as specific diagnostic challenges. Working closely with infectious disease specialists is the best way to achieve optimum care for this…

Filed under:ConditionsPractice Support Tagged with:arthralgiascombination antiretroviral therapyDiagnosisdrug interactionHIVMyopathypatient careRheumatic Diseaserheumatologistrheumatologytreament

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