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Search results for: psoriasis

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Medical Paradoxes in Clinic, Lab Should Encourage Physicians to Reappraise Ideas about Health and Disease

Simon M. Helfgott, MD  |  January 19, 2017

Wash your hands. This most basic tenet of proper hygiene has been drummed into our heads for years. It’s an obvious infection prevention activity, yet for years, compliance among physicians and other caregivers has been lackluster. To rectify this matter, regulatory agencies began auditing hospital staff adherence to this axiom of infection prevention. Not only…

Filed under:OpinionResearch RheumRheuminationsSpeak Out Rheum Tagged with:clinicDietDiseaseDrugslaboutcomeparadoxpatient careResearchrheumatologistrheumatologySmoking

Rheumatology Drug Updates: Giant Cell Arteritis Relapse Possible if Tocilizumab Discontinued; Plus Updates on Rituximab, Etanercept

Michele B. Kaufman, PharmD, BCGP  |  January 19, 2017

GCA Relapse Possible When Discontinuing Tocilizumab In a Phase 2 randomized, controlled trial, tocilizumab, an anti-IL-6 biologic agent, was shown to induce and maintain remission for up to 52 weeks in patients with giant cell arteritis (GCA).1 During this trial, patients with GCA were randomized in a 2:1 ratio to receive 8 mg/kg bodyweight tocilizumab…

Filed under:Drug UpdatesResearch Rheum Tagged with:ApprovalsdrugetanerceptFDAGiant Cell Arteritisoutcomepatient careQualityrelapseResearchrheumatologyrituximabSafetytrial

Psoriatic Arthritis Linked to Increased Heart Disease Risk

Carolyn Crist  |  January 17, 2017

(Reuters Health)—Arthritis that accompanies the skin condition psoriasis may also come with a higher risk of heart problems, according to a Hong Kong study. In particular, patients with psoriatic arthritis may have a three- to four-fold higher prevalence of coronary atherosclerosis. Clinicians need to identify patients with high cardiovascular (CV) risk so they can provide…

Filed under:ConditionsPsoriatic Arthritis Tagged with:coronary plaqueHeart DiseaseNational Psoriasis FoundationPsoriasisPsoriatic Arthritis

Step Therapy, Biosimilars among ACR’s 2017 State-Level Priorities

Kelly Tyrrell  |  January 17, 2017

Opportunities and challenges will continue to face the rheumatology community in 2017. In response to these challenges, the ACR has outlined its federal– and state-level legislative and regulatory healthcare priorities for the year. Howard Blumstein, MD, chair of the ACR Affiliate Society Council, says that achieving at least some of these priorities at the state…

Filed under:Legislation & AdvocacyProfessional Topics Tagged with:Biosimilarsprior authorizationspecialty tieringstep therapy

Guselkumab Improves Active Psoriatic Arthritis

Michele B. Kaufman, PharmD, BCGP, & Lara C. Pullen, PhD  |  January 11, 2017

A study showed that guselkumab may decrease symptoms of psoriatic arthritis and improve quality of life in adult patients…

Filed under:Biologics/DMARDsDrug Updates

The OPAL Beyond Study: Tofacitinib Phase 3 Results Positive for Treating PsA

Michele B. Kaufman, PharmD, BCGP  |  December 20, 2016

In a recent study, patients with psoriatic arthritis taking tofacitinib had a decrease in disease activity compared with placebo…

Filed under:ConditionsDrug UpdatesPsoriatic Arthritis Tagged with:Disease-modifying antirheumatic drugs (DMARDs)Janus Kinase InhibitorsPsoriatic ArthritisTofacitinib

Obesity & Rheumatic Disease

Richard Quinn  |  December 9, 2016

“Obesity is an inflammatory state, so it is in the landscape of the rheumatologist,” says Christopher Ritchlin, MD, MPH. And the more attention rheumatologists pay to obesity, the better…

Filed under:Conditions Tagged with:DietinflammationObesitypreventiveRheumatic Disease

FDA Update on Rituximab & Etanercept; Plus New ACP Gout Guideline

Michele B. Kaufman, PharmD, BCGP  |  November 30, 2016

The FDA is considering an application for subcutaneous rituximab and has approved an application for etanercept to treat pediatric patients with plaque psoriasis…

Filed under:Biologics/DMARDsConditionsDrug UpdatesGout and Crystalline ArthritisPediatric Conditions Tagged with:American College of PhysiciansetanerceptFDAFood and Drug AdministrationGoutguidelinePediatricplaque psoriasisrituximab

2015 Treatment Recommendation Updates for Psoriatic Arthritis Address Comorbidities, New Medications

Mary Beth Nierengarten  |  November 16, 2016

In May, the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) published its recommendations for the treatment of psoriatic arthritis (PsA).1 The updated recommendations represent advances in drug development and availability since previous recommendations published in 2009, as well changes in treatment paradigms and the importance of associated aspects of the disease.2…

Filed under:ConditionsOther Rheumatic ConditionsPsoriatic Arthritis Tagged with:ClinicalcomorbiditiesdrugGroup for Research and Assessment of Psoriasis and Psoriatic ArthritisguidelineManagementMedicationPsoriasisPsoriatic Arthritisrecommendationtherapy

Treating the Athlete: New Thoughts on How to Prevent & Treat Arthritis in Athletes & Raise Their Awareness

Karen Appold  |  November 4, 2016

All athletes—amateur and professional—should understand their risks for developing injury-related arthritis. Rheumatologists and other physicians at the Hospital for Special Surgery in New York take a rapid approach to treating athletes, often considering intense physical therapy, innovative treatments and surgery much sooner than for the average patient—all to keep joints healthy and enable athletes to play for as long as possible…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:Exercise/physical therapyinjuryphysical fitnessPhysical Therapysecukinumab

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