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Articles tagged with "GCA"

Race May Not Be a Risk Factor for Giant Cell Arteritis

Lara C. Pullen, PhD  |  October 21, 2019

Past research has identified being of Northern European descent as a risk factor, among others such as age, sex and HLA DRB1, for developing giant cell arteritis (GCA). But new research casts doubts on this idea, finding that rates of biopsy proven GCA may not differ by race…

Large-Vessel Involvement Is an Independent Risk Factor Predicting GCA Mortality

Carina Stanton  |  February 14, 2019

At diagnosis, temporal artery biopsy results and large-vessel involvement of patients with giant cell arteritis may be stronger predictors of mortality than cardiovascular risk factors…

New Recommendations Guide Imaging in Large-Vessel Vasculitis

Reuters Staff  |  February 5, 2018

NEW YORK (Reuters Health)—Patients with suspected large-vessel vasculitis (LVV) should undergo early imaging, the European League Against Rheumatism (EULAR) advises in a new report presenting a dozen evidence-based recommendations for the use of imaging in primary LVV. Ultrasound should be the first choice for giant-cell arteritis (GCA), while MRI should take precedence for Takayasu arteritis…

Tocilizumab Is Effective to Treat GCA

Lara C. Pullen, PhD  |  August 28, 2017

In a recent clinical trial, tocilizumab helped sustain glucocorticoid-free remission in patients with giant cell arteritis. Patients also received a prednisone taper, and 50% of tocilizumab-treated patients achieved prednisone-free remission and were less likely to experience disease flare compared with placebo…

FDA Considers Tocilizumab for GCA & Piclidenoson Enters Phase 3 Trial for RA, Psoriasis

Michele B. Kaufman, PharmD, BCGP  |  February 27, 2017

The FDA is considering a supplemental biologics license application for tocilizumab to treat giant cell arteritis…

How to Manage Patients with Giant Cell Arteritis and Polymyalgia Rheumatica

Thomas R. Collins  |  January 18, 2017

WASHINGTON, D.C.—From diagnosis questions to infection risk to treatment decisions, handling giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) comes with a range of challenges for clinicians. Speaking in the ACR Review Course at the 2016 ACR/ARHP Annual Meeting, an expert—Rebecca Manno, MD, MHS, assistant professor of medicine in rheumatology at Johns Hopkins, as well…

GCA Relapse Possible When Discontinuing Tocilizumab

Michele B. Kaufman, PharmD, BCGP  |  December 14, 2016

A recent study found that although patients with giant cell arteritis respond positively to long-term tocilizumab treatment, relapse may occur after discontinuing the medication…

Diagnose, Manage and Treat Giant Cell Arteritis

Gretchen Henkel  |  July 1, 2014

A rheumatologist at the California Rheumatology Alliance 10th Annual Medical & Scientific Meeting in San Francisco shares research findings on this inflammatory blood vessel disease

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