New research shows the accumulation of regulatory T cells in damaged muscle corresponds with a switch in the myeloid cell infiltrate from a proinflammatory to a proregenerative phenotype.
Rheumatologists on the Move
Awards, appointments and announcements in the world of rheumatology
Rheuminations: Ankylosing Spondylitis Sometimes Defies Detection
How method of diagnosing, treating this inflammatory back disease characterized by stiffness and the presence of HLA-B27 gene has evolved
Rheumatologists Make Progress Defining Spectrum of Axial Spondyloarthritis
New research clarifies terminology used for diagnosis, but questions remain around epidemiology, genetics and management of patients with axial skeletal inflammation
MicroRNA-Based Therapeutics Hold Promise Against Lupus, Other Rheumatic Diseases Note Experts at the ACR/ARHP’s 2013 Annual Meeting
Studies suggest deregulation, dysfunction of miRNAs in human, mice models of lupus may be future targets for gene therapy
Treating Early-Stage Spondyloarthritis May Prevent Disease Progression, Say Researchers at the ACR/ARHP Winter Rheumatology Symposium
Therapy with tumor necrosis factor inhibitors, nonsteroidal antiinflammatory drugs, ustekinumab in early stages of osteitis may halt molecular switching to bone-forming phenotype characteristic of SpA
Rheumatology Research Foundation to Play Role in Developing New RA, Lupus Treatments
Foundation joins Accelerating Medicines Partnership, led by National Institutes of Health, to fast-track viable potential drug therapies for lupus, rheumatoid arthritis
Research Into Causes of Systemic Vasculitis May Lead to Targeted Treatments Say Rheumatologists at the 2013 ACR/ARHP Annual Meeting
Studies focused on role of the immune system in disease development, and contributing genetic and environmental factors, may elicit better therapeutic approaches to small- and large-vessel vasculitis
Switches That Regulate Gene Expression Offer Better Understanding of Rheumatic Disease Say Experts at the 2013 ACR/ARHP Annual Meeting
New studies examine why turning on or off switches in genes that control the genome can contribute to pathogenesis of such autoimmune diseases as systemic lupus erythematosus or rheumatoid arthritis
Evolutionary Medicine Provides Insight into the Chronic Inflammatory State Note Rheumatologists at the 2013 ACR/ARHP Annual Meeting
Studies on metabolism, neuroendocrinology, and immunology can broaden understanding of the pathophysiology of chronic inflammatory diseases
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