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Search results for: NSAIDs

Do NSAIDs Mask MRI Findings in Patients with Axial Spondyloarthritis?

Michele B. Kaufman, PharmD, BCGP  |  July 17, 2023

Research suggests the use of non-steroidal anti-inflammatory drugs may mask the amount of sacroiliac joint inflammation found on MRI in patients with axial spondyloarthritis.

Filed under:Biologics/DMARDsDrug UpdatesMeeting Reports Tagged with:AS Resource CenteraxSpAMagnetic resonance imaging (MRI)MRIsacroiliac jointssacroiliitis

Study Finds NSAIDs Raise Heart Disease Risk in Osteoarthritis Patients

Susan Bernstein  |  February 16, 2021

In a controlled, large-cohort, longi­tudinal study from Canada, Atiquazzaman et al. found that use of non-steroidal anti-inflammatory drugs (NSAIDs) substantially contributes to increased cardiovascular disease risk among people with osteoarthritis (OA).1  This is the first study to evaluate the mediating role that NSAIDs play in the association between OA and cardiovascular disease (CVD), and the…

Filed under:ConditionsOsteoarthritis and Bone DisordersResearch Rheum Tagged with:Cardiovascular diseaseNonsteroidal anti-inflammatory drugs (NSAIDs)

FDA Warning: Avoid Use of NSAIDs after Week 20 of Pregnancy

Michele B. Kaufman, PharmD, BCGP  |  October 28, 2020

The FDA is recommending pregnant women avoid using NSAIDs as early as week 20 of pregnancy due to the risk of kidney problems in a developing fetus.

Filed under:Drug Updates Tagged with:FDAkidneypregnancyRenalsafety warningU.S. Food and Drug Administration (FDA)warning

Study Examines Why Patients Exceed Recommended Doses of Ibuprofen & NSAIDs

Michele B. Kaufman, PharmD, BCGP  |  April 2, 2018

A recent study examined how often patients exceed the dosing limits of nonsteroidal anti-inflammatory drugs and identified the characteristics of the patients most likely to exceed recommended doses…

Filed under:AnalgesicsDrug Updates Tagged with:dosageNonsteroidal anti-inflammatory drugs (NSAIDs)NSAIDsPain Management

Opioids No Better Than NSAIDs for Chronic Back or Arthritis Pain

Lisa Rapaport  |  March 7, 2018

(Reuters Health)—Acetaminophen, ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) are better than opioids at easing the intensity of chronic pain in the back, knees or hips, a U.S. experiment suggests. And opioids are no better than these other drugs at reducing how much pain interferes with daily activities, such as walking, working, sleeping or enjoying…

Filed under:AnalgesicsConditionsDrug UpdatesPain Syndromes Tagged with:Chronic painhiphip painKnee Osteoarthritis (OA)Nonsteroidal anti-inflammatory drugs (NSAIDs)NSAIDsOpioidsosteoarthritis (OA)PainPain Management

Diclofenac Patch, Piroxicam Most Effective Topical NSAIDs for Osteoarthritis

Reuters Staff  |  February 28, 2018

NEW YORK (Reuters Health)—Diclofenac patches appear to be the most effective topical nonsteroidal anti-inflammatory drug (NSAID) for osteoarthritis (OA), according to a new systematic review and network meta-analysis. “Topical NSAIDs were effective and safe for OA,” Dr. Weiya Zhang of the University of Nottingham and City Hospital in the UK and colleagues write. “However, confirmation…

Filed under:Drug UpdatesOsteoarthritis and Bone Disorders Tagged with:diclofenac patchosteoarthritis (OA)piroxicamtopical NSAIDs

NSAIDs Increase MI Risk; Plus New Label Warnings for Canagliflozin

Michele B. Kaufman, PharmD, BCGP  |  May 29, 2017

NSAIDs Increase Myocardial Infarction Risk According a recent meta-analysis of real-world non-steroidal anti-inflammatory drug (NSAID) use, NSAIDs may increase the risk of acute myocardial infarction (AMI). The analysis used individual patient data meta-analysis of studies from healthcare databases in Canada, Finland and the U.K. to determine the time course for risk of AMI, as well…

Filed under:AnalgesicsDrug Updates Tagged with:canagliflozindiabetesFDAFood and Drug AdministrationheartMyocardial infarctionNonsteroidal anti-inflammatory drugs (NSAIDs)NSAIDs

NSAIDs Effective for Early Axial Spondyloarthritis

Reuters Staff  |  June 10, 2016

NEW YORK (Reuters Health)—Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective, but underused, in patients with early axial spondyloarthritis, researchers from France report. NSAIDs are the cornerstone of treatment of axial spondyloarthritis, but there is often a trade-off between prescribing doses high enough to decrease pain and other symptoms vs. keeping the doses low enough to decrease…

Filed under:AnalgesicsDrug Updates Tagged with:axial spondyloarthritis (SpA)Nonsteroidal anti-inflammatory drugs (NSAIDs)NSAIDsPain

New Guideline: NSAIDs Effective in Treating Ankylosing Spondylitis & Nonradiographic Axial Spondyloarthritis

Richard Quinn  |  May 6, 2016

In February, new recommendations were released for the treatment of ankylosing spondylitis and nonradiographic axial spondyloarthritis, noting that NSAIDs may be the best initial treatment for the diseases, with TNF inhibitors as second-line therapies. The guideline was the result of a joint effort by the ACR, the Spondylitis Association of America and the Spondyloarthritis Research and Treatment Network…

Filed under:Axial SpondyloarthritisConditionsResearch Rheum Tagged with:Ankylosing SpondylitisArthritis & Rheumatologyaxial spondyloarthritis (SpA)GuidelinesNonsteroidal anti-inflammatory drugs (NSAIDs)NSAIDs

FDA Issues Stronger Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Warning

Michele B. Kaufman, PharmD, CGP, RPh  |  October 14, 2015

The U.S. Food and Drug Administration (FDA) has toughened the existing warnings for nonsteroidal anti-inflammatory drugs (NSAIDs) due to their stroke and myocardial infarction (MI) risk increase.1 Due to a continual review of these products, FDA is requiring label updates for all prescription NSAIDs. Over-the-counter (OTC) NSAIDs already list the increased risk of MI and…

Filed under:ConditionsDrug UpdatesOther Rheumatic ConditionsResearch Rheum Tagged with:abaloparatideadverse eventsanti-inflammatoryclinical trialsdrugFDAMIMyocardial infarctionnonsteroidal anti-inflammatory drugsNSAIDsoutcomeResearchrheumatologyriskSafetystroketofacitinib citrate

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