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Search results for: fatigue

Study: Patients with PMR Experience Fatigue, Sleep Disturbance & Mood Disorders

Jessica Leung, MBBS, FRACP, Claire E. Owen, MBBS, PhD, FRACP, David Liew, MBBS, FRACP, & Russell Buchanan, MBBS, MD, FRACP  |  January 24, 2024

Background/Purpose Polymyalgia rheumatica (PMR) is typified by pain and stiffness of the shoulder and hip girdles. Previous qualitative studies have highlighted the importance to patients of additional symptoms, including fatigue and sleep disturbance. These features of PMR are less recognized by clinicians and have not yet been quantified in the literature. Further, the adequacy of…

Filed under:Biologics/DMARDsConditionsDrug UpdatesOther Rheumatic ConditionsResearch Rheum Tagged with:PMR FocusRheumPolymyalgia Rheumatica

Non-Pharmacological Interventions & Management of RA-Related Fatigue

Lara C. Pullen, PhD  |  January 13, 2020

Often, rheumatoid arthritis (RA) patients struggle with fatigue, and the cause of the fatigue remains unclear. Past research suggests RA-related fatigue may be moderately improved by physical activity. A recent narrative review supports these prior findings, noting that patients also benefit moderately from psychosocial interventions…

Filed under:ConditionsRheumatoid Arthritis Tagged with:fatiguephysical activityRheumatoid Arthritis (RA)

Scientists May Be Closer to A Blood Test for Chronic Fatigue Syndrome

Kate Kelland  |  April 30, 2019

LONDON (Reuters)—Scientists in the U.S. say they have taken a step toward developing a possible diagnostic test for chronic fatigue syndrome, a condition characterized by exhaustion and other debilitating symptoms. Researchers at Stanford University School of Medicine say a pilot study of 40 people, half of whom were healthy and half of whom had the…

Filed under:Conditions Tagged with:assaychronic fatigue syndromeTest

Study Finds Chronic Fatigue Clues in Overactive Immune Response

Kate Kelland  |  December 17, 2018

LONDON (Reuters)—Scientists exploring what may trigger chronic fatigue syndrome (CFS) have found clues in the way some people’s immune systems respond to interferon alpha.1 The researchers used the drug to create a model of the disease in people without CFS but with hepatitis C. Many patients who receive interferon alpha experience extreme fatigue during treatment,…

Filed under:ConditionsResearch Rheum Tagged with:chronic fatigue syndromemyalgic encephalomyelitis

Does the Metal-Fatigue Principle Apply to Elderly Bones?

Mary Beth Nierengarten  |  August 16, 2018

Can principles from engineering provide a broader understanding of how the human skeleton works and be used to help prevent a common and often consequential event for people as they age—bone fractures? Research from a team of investigators that includes orthopedic surgeons and mechanical engineers suggests that, yes, looking at how engineered materials, such as…

Filed under:Conditions Tagged with:bonebone breakbone remodelingFractures

Study Finds Pedometers Reduce Fatigue in RA Patients

Mary Beth Nierengarten  |  April 26, 2018

For people with rheumatoid arthritis (RA), fatigue can be a debilitating symptom that interferes with daily life and significantly reduces quality of life. Managing fatigue can be difficult; it is linked to disease activity and a host of other conditions that commonly accompany RA, such as depression, sleep problems and obesity. A new study, however,…

Filed under:Rheumatoid Arthritis Tagged with:fatiguepedometersphysical activityRheumatoid arthritis

Physical Assessment of Chronic Fatigue Syndrome: It Just May Work

Lara C. Pullen, PhD  |  January 15, 2018

A recent U.K. study assessed the use of the Perrin technique to diagnose chronic fatigue syndrome based on five physical signs of disease. Overall, researchers found the accuracy of diagnosis by allied health professionals was highest when using tests for only two signs: tender coelic plexus and postural/mechanical disturbances of the thoracic spine…

Filed under:Conditions Tagged with:chronic fatigue syndromeDiagnosismyalgic encephalomyelitisPerrin technique

Pedometers & RA: Does Increasing Physical Activity Decrease Fatigue?

Arthritis Care & Research  |  January 2, 2018

Recent research examined the effectiveness of a pedometer-based intervention for managing fatigue in patients with rheumatoid arthritis (RA). During the 21-week trial, RA patients using pedometers successfully increased their physical activity, with a greater than 30% decrease in the proportion of participants classified as sedentary. Patients also decreased their reported fatigue, and some reported improvements in function, pain, depressive symptoms and disease activity levels…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:Arthritis Care & ResearchExercisefatiguepedometersRheumatoid Arthritis (RA)walking

A Defect in Mitochondrial Function May Underlie Chronic Fatigue Syndrome

Lara C. Pullen, PhD  |  January 1, 2018

The peripheral blood mononuclear cells (PBMCs) of patients with chronic fatigue syndrome (CFS) may be unable to meet certain energetic demands, according to a U.K. study. Researchers found that PBMCs in healthy individuals may adapt to environmental stressors by enhancing their ability to increase ATP production through mitochondrial respiration, but not in patients with CFS…

Filed under:Conditions Tagged with:chronic fatigue syndromeenvironmentalenvironmental factorMitochondrial Function

Chronic Fatigue Syndrome: Are There Different Phenotypes?

Lara C. Pullen, PhD  |  December 18, 2017

New research has examined the autonomic parameters of patients with chronic fatigue syndrome (CFS) using the DePaul Symptom Questionnaire to place patients on a disease spectrum. Researchers found different groups of CFS patients had different levels of autonomic dysfunction and cognitive impairment, suggesting that different CFS criteria may diagnose a spectrum of disease severities and different CFS phenotypes…

Filed under:Uncategorized Tagged with:autonomic nervous systemchronic fatigue syndromephenotype

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