A single treatment with recombinant acid ceramidase improves the chondrogenic phenotype of primary chondrocytes and leads to an increased yield of mesenchymal stem cells. (posted July 31, 2013)
B-Cell Genes Interact to Increase Risk for Rheumatoid Arthritis
Researchers demonstrate that BANK1 is a susceptibility gene for RA, and it may play a role in RA pathogenesis. (posted June 31, 2013)
Rheumatology Drug Research Should Focus on Particular Groups of Patients
An analysis of risks and benefits of drugs in specific types of patients will help rheumatologists provide better treatment
California Rheumatology Alliance 2013 Meeting: The Future of Rheumatoid Arthritis
Treatment for RA should involve targeting subclinical disease and reversing immune dysregulation, expert says
Researchers Explore HLA-B27’s Role in the Development of Spondylitis
New research reports on the increased sensitivity of human-HLA-B27 transgenic rat bone marrow monocytes to TNF-α stimulation and osteoclast differentiation. (posted June 27, 2013)
Can Lubricating Joints Prevent Osteoarthritis?
Proteoglycan 4 (Prg4), also known as lubricin, could slow the process of cartilage destruction in osteoarthritis. (posted June 13, 2013)
Small Fiber Function May Be Linked to Fibromyalgia
Researchers show, for the first time, that small fiber function and morphology is impaired in patients with fibromyalgia. (posted June 18, 2013)
Th17 May Contribute to Bone Destruction by Modifying Osteoclasts
New research describes the role of RANKL-expressing Th17 cells in inflammatory bone destruction. (posted June 3, 2013)
Advances in Genomics, Bioinformatics Draw New Insights From the Human Genome
Widely held belief that large segments of the human genome consist of ‘junk DNA’ is incorrect, say scientists
Arthritis Care & Research Celebrates 25 Years
From its beginnings as a quarterly journal in 1988, to a successful monthly publication today, AC&R has evolved and thrived
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