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You are here: Home / Search for "psoriasis"

Search results for: psoriasis

TNF Inhibitor Tied to Lower Cardiovascular Risk in Psoriasis

November 22, 2016 • By Lorraine L. Janeczko

NEW YORK (Reuters Health)—Psoriasis patients treated with tumor necrosis factor-alpha (TNF) inhibitors may have a lower risk of major cardiovascular (CV) events than those treated with methotrexate (MTX), according to a new study. “The findings do not surprise me. TNF inhibitors control inflammation better than methotrexate,” lead author Dr. Jashin J. Wu of Kaiser Permanente… [Read More]

Filed Under: Biologics & Biosimilars, Drug Updates Tagged With: cardiovascular, heart, metho­trexate, Psoriasis, TNF, TNF inhibitor

Sarilumab Approval Stalled; Piclidenoson Promising for Psoriasis

November 16, 2016 • By Michele B. Kaufman, PharmD, BCGP

Due to manufacturing deficiencies found during a routine inspection by the FDA, approval of sarilumab for treating RA has slowed until facility issues are resolved…... [Read More]

Filed Under: Biologics & Biosimilars, Drug Updates Tagged With: apremilast, piclidenoson, Psoriasis, Rheumatoid Arthritis (RA), sarilumab

Psoriasis May Carry Atherosclerosis Risk Similar to that with Diabetes

September 5, 2016 • By Kathryn Doyle

(Reuters Health)—People with psoriasis may be at increased risk of coronary artery calcium buildup, comparable to that of people with diabetes, according to a new study. Comparing people in their 50s with psoriasis, diabetes or neither disease, researchers found that moderate to severe calcium buildup was about five times as common in people with diabetes… [Read More]

Filed Under: Conditions, Systemic Inflammatory Syndromes Tagged With: coronary artery calcium, diabetes, Heart Disease, Psoriasis, risk, type II diabetes

Ixekizumab Improves Work Productivity in Patients with Plaque Psoriasis

August 10, 2016 • By Michele B. Kaufman, PharmD, BCGP

In three clinical trials, ixekizumab proved more effective than placebo or etanercept at increasing the work attendance and productivity of patients with plaque psoriasis…... [Read More]

Filed Under: Biologics & Biosimilars, Drug Updates Tagged With: ixekizumab, plaque psoriasis, productivity, Psoriasis, Workforce

U.S. FDA Panel Backs Valeant Psoriasis Drug with Risk Program

July 21, 2016 • By Toni Clarke

(Reuters)—Valeant Pharmaceuticals International Inc.’s experimental drug to treat psoriasis should be approved as long as certain measures are put in place to mitigate the risk of suicide, an advisory committee to the U.S. Food and Drug Administration concluded on Tuesday. The FDA is not obliged to follow the advice of its advisory committees but typically… [Read More]

Filed Under: Biologics & Biosimilars, Drug Updates Tagged With: brodalumab, FDA, Food and Drug Administration, Psoriasis, Safety

Tildrakizumab Promising for Plaque Psoriasis; FDA Approves Adalimumab to Treat Panuveitis

July 20, 2016 • By Michele B. Kaufman, PharmD, BCGP

n clinical trials, tildrakizumab was more effective than etanercept and placebo at treating moderate to severe plaque psoriasis. Adalimumab has received approval for treating non-infectious intermediate, posterior and panuveitis—its 10th FDA indication…... [Read More]

Filed Under: Biologics & Biosimilars, Drug Updates Tagged With: adalimumab, etanercept, FDA, Food and Drug Administration, panuveitis, plaque psoriasis, tildrakizumab

Valeant Psoriasis Drug’s Suicide Risk Hard to Assess, Say FDA Staff

July 15, 2016 • By Reuters Staff

(Reuters)—Valeant Pharmaceuticals International Inc.’s experimental drug to treat psoriasis carries a potential risk of suicide that is challenging to assess due to limited data, a preliminary review by the U.S. Food and Drug Administration said on Friday. The review comes two days ahead of a meeting of outside experts who will advise the FDA on… [Read More]

Filed Under: Drug Updates, Rheumatoid Arthritis, Systemic Inflammatory Syndromes

Patients with PsA, Cutaneous Psoriasis May Undergo Hip Replacement

July 15, 2016 • By Richard Quinn

A recent study of patients with psoriatic arthritis and cutaneous psoriasis found that these patients do not have a higher risk of worse outcomes after total hip arthroplasty compared with patients with osteoarthritis…... [Read More]

Filed Under: Conditions, Systemic Inflammatory Syndromes Tagged With: Arthritis & Rheumatology, hip, hip arthroplasty, hip replacement, Psoriasis, psoriatic arthritis

Family History Biggest Predictor of Heart Attacks in People with Psoriasis

July 2, 2016 • By Lisa Rapaport

(Reuters Health)—People with psoriasis, a chronic inflammatory disease, are more likely to have heart attacks and strokes when they have a family history of cardiovascular problems, a Danish study suggests. Psoriasis wasn’t associated with higher risk of heart attacks or strokes when people with the skin condition didn’t have a family history of cardiovascular disease,… [Read More]

Filed Under: Conditions, Systemic Inflammatory Syndromes Tagged With: cardiovascular, heart, Psoriasis

Rheumatology Drug Updates: Etanercept for Pediatric Plaque Psoriasis

June 13, 2016 • By Michele B. Kaufman, PharmD, BCGP

Etanercept Submitted for Chronic, Severe Plaque Psoriasis in Children The U.S. Food and Drug Administration (FDA) has accepted the supplemental Biologics License Application for etanercept (Enbrel) for treating pediatric patients with chronic, severe plaque psoriasis.1 The application was submitted in early January 2016 and is based on results of a one-year Phase 3 study with… [Read More]

Filed Under: Biologics & Biosimilars, Conditions, Drug Updates, Osteoarthritis, Systemic Inflammatory Syndromes Tagged With: Approval, AXS-02, biologic, biosimilar, clinical trial, drug, etanercept, FDA, knee pain, Osteoarthritis, Pediatric, plaque, Psoriasis, rheumatology, Safety

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