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Search results for: Janus kinase inhibitors

Conservation of Drugs: The Impact of Acute Immunomodulator Prescribing for COVID-19 on Rheumatology Patients

Sara Jo Santangelo, PharmD candidate, & Wendy Ramey, BSPharm, RPh, CSP  |  May 23, 2022

In its COVID-19 treatment guidelines, the National Institutes of Health (NIH) lists several drugs commonly prescribed for patients with rheumatic conditions as potential therapies in those who are hospitalized for COVID-19 and require high-flow oxygen, noninvasive ventilation, intermittent ventilation (IMV) or extracorporeal membrane oxygenation (ECMO), as of Aug. 25, 2021, and current as this is…

Filed under:Drug UpdatesInterprofessional Perspective Tagged with:baricitinibCOVID-19immunomodulatory agentInterprofessional PerspectivesarilumabtocilizumabTofacitinib

Medication Preferences & Current Practices for PsA

Michele B. Kaufman, PharmD, BCGP  |  May 11, 2022

With many new agents designed to treat PsA, rheumatologists and patients have options. Schwartzman et al. examined the real-world use of different treatments and ranked patient medication preferences.

Filed under:ACR ConvergenceConditionsDrug UpdatesMeeting ReportsPsoriatic Arthritis Tagged with:ACR Convergence 2021PsAPsoriatic Arthritis

Risk of Adverse Outcomes Due to COVID-19 May Be Lower with TNF Inhibitor Monotherapy

Katie Robinson  |  May 5, 2022

Findings support the continued use of TNF inhibitor monotherapy in individuals with immune-mediated inflammatory diseases. In the study, these patients had a lower risk of hospitalization or death caused by COVID-19 than patients on other commonly prescribed treatment regimens

Filed under:Conditions Tagged with:COVID-19COVID-19 Global Rheumatology Allianceimmune-mediated inflammatory diseases (IMIDs)monotherapyTNF inhibitors

2 New Clinical Practice Guidelines for JIA Released

Ruth Jessen Hickman, MD  |  April 20, 2022

Two new ACR Clinical Practice Guidelines provide recommendations on the pharmacologic management of JIA, focusing on treatment of oligoarthritis, temporomandibular arthritis & systemic JIA, as well as nonpharmacologic therapies, medication monitoring, immunizations & imaging.

Filed under:Uncategorized

Order in the Inflammatory Mess: RheumMadness 2022 Cytokine Networks Scouting Report

Rheumatology Leadership Team: David Leverenz, MD; Akrithi Udupa, MD; Guy Katz, MD; Lauren He, MD; Ben Kellog, MD; Michael Macklin, MD; Courtney Bair; Matthew Sparks, MD; & Lisa Criscione-Schreiber, MD, MEd  |  February 8, 2022

Research has identified and described a pro-inflammatory cytokine network shared by four rheumatic conditions that may be particularly active in patients with severe disease.

Filed under:Uncategorized Tagged with:cellscytokine networksCytokinesRheumMadness

ACR Town Hall Provides Update on Oral Antiviral Therapy for COVID-19

Katie Robinson  |  January 24, 2022

At an ACR COVID-19 town hall on COVID-19, infectious disease experts discussed the most up-to-datecurrent information on pre- and post-exposure monoclonal antibody therapy, oral antivirals and vaccines for rheumatology patients.

Filed under:Conditions Tagged with:COVID-19immunosuppressive drugsmonoclonal antibodyvaccine

Insights into JAK Inhibitor Use

Michele B. Kaufman, PharmD, BCGP  |  January 20, 2022

According to a German study presented during ACR Convergence 2021, treatment persistence with JAK inhibitors is comparable to TNF inhibitors and other bDMARDs among patients with rheumatoid arthritis.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2021ACR Convergence 2021 – RAJAK inhibitorsRheumatoid Arthritis (RA)

Updates on JAK Inhibitor Safety, COVID-19 Vaccination in Immunosuppressed Patients & More

Jeffrey Curtis, MD, MS, MPH  |  December 7, 2021

ACR CONVERGENCE 2021—The ACR Convergence 2021 meeting reflected the continued advancement of science and practical research in the field of rheumatoid arthritis (RA). Among the most important topics this year in RA was the evolution of the risk-benefit profile of Janus kinase (JAK) inhibitors, for which new safety data emerged in a series of related…

Filed under:ACR ConvergenceConditionsMeeting ReportsResearch RheumRheumatoid Arthritis Tagged with:ACR Convergence 2021ACR Convergence 2021 – RA

Management of Inflammatory Myositis: Options for Refractory Disease & New Therapies Discussed

Mary Beth Nierengarten  |  December 2, 2021

Options to escalate treatment for refractory inflammatory myositis and new therapies in the pipeline are discussed.

Filed under:ACR ConvergenceConditionsMeeting ReportsMyositis Tagged with:ACR Convergence 2021myositispatient care

FDA Discussed 2021 Drug Warnings & Approvals at ACR Annual Meeting

Thomas R. Collins  |  December 1, 2021

ACR Convergence 2021—The recent Boxed Warning requirement applied to three Janus kinase (JAK) inhibitors, cautioning doctors and patients about several major risks in patients with rheumatoid arthritis, came only after rigorous data collection and careful consideration of the risks and the benefits, U.S. Food & Drug Administration (FDA) officials said in November at ACR Convergence…

Filed under:ACR ConvergenceConditionsDrug UpdatesMeeting ReportsRheumatoid Arthritis Tagged with:ACR Convergence 2021ACR Convergence 2021 – RAavacopanbaricitinibJAK inhibitorsTofacitinibupadacitinib

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