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Search results for: Janus kinase inhibitors

Updates in Juvenile Dermatomyositis: Pathogenesis & Patient Care

Jason Liebowitz, MD, FACR  |  July 17, 2021

Experts provided an update on juvenile dermatomyositis, discussing patient care, treatment options and the pathogenesis of disease.

Filed under:ConditionsMeeting Reports Tagged with:juvenile dermatomyositisPathogenesisPediatric RheumatologyPediatric Rheumatology SymposiumPRSYM

Manifestations of JIA: JIA-Associated Uveitis, sJIA & Lung Involvement in sJIA

Jason Liebowitz, MD, FACR  |  July 16, 2021

JIA can manifest in a variety of ways. Experts discuss the implications of uveitis, systemic disease and lung involvement in sJIA.

Filed under:ConditionsMeeting Reports Tagged with:eyesJIA-associated uveitisjuvenile idiopathic arthritis (JIA)lungsPediatric RheumatologyPediatric Rheumatology SymposiumPRSYMsJIAsJIA-associated lung disease

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How Immunosuppression May Affect COVID-19 Vaccine Response

Ruth Jessen Hickman, MD  |  June 13, 2021

Although we can expect to learn much more, preliminary data are now available on the potential safety and effectiveness of COVID-19 vaccines in rheumatology patients. The picture is likely to be nuanced, with not all types of immuno­suppressive treatments having identical impacts on vaccine response. Rheumatologists should use caution in interpreting early reports, while continuing…

Filed under:Conditions Tagged with:COVID-19immunosuppressionvaccination

Myositis Management: Clinical Trials Provide New Insights into Treatment Options

Jason Liebowitz, MD, FACR  |  May 24, 2021

Advancements in the treatment of myositis are on their way, according to Hector Chenoy, PhD, FRCP, who outlined the latest clinical trials during the 2021 ACR State-of-the-Art Clinical Symposium.

Filed under:ConditionsMeeting ReportsMyositis Tagged with:ACR State-of-the-Art Clinical Symposiumjakinibmyositis

Highlights, Pearls & News from ACR Convergence 2020

Vanessa Caceres  |  March 15, 2021

ACR CONVERGENCE 2020—In a year like no other, the 2020 virtual ACR Convergence was a meeting like no other. Nonetheless, the meeting introduced a healthy mix of clinical insights and take-home pearls, according to panelists in the meeting’s closing session, Bright Future: Discovery & Growth.  In this session, panelists discussed some of the biggest news…

Filed under:ConditionsRheumatoid ArthritisSystemic Lupus Erythematosus Tagged with:ACR Convergence 2020COVID-19Diet

Cytokine Targets & Treatment Developments for Psoriatic Arthritis & Spondyloarthritis

Carina Stanton  |  March 15, 2021

ACR CONVERGENCE 2020—In recent years, a pathophysiological role for the interleukin (IL) 17/IL-23 axis in the development of psoriasis, enthesitis and inflammatory arthritis has been investigated in both rodent and human models. Clinical trials have demonstrated differential benefits for skin disease and joint disease in patients with psoriatic arthritis, axial spondyloarthritis (axSpA) and ankylosing spondylitis…

Filed under:Axial SpondyloarthritisConditionsPsoriatic Arthritis Tagged with:ACR Convergence 2020Ankylosing SpondylitisIL-17/IL-23 CytokineJanus Kinase InhibitorsPsoriatic Arthritis

Tips for Balancing Medication Treatment & Risk in Elderly Patients

Thomas R. Collins  |  March 15, 2021

ACR CONVERGENCE 2020—With the inevitable decline in organ function that comes with age, and the likelihood that older patients (i.e., generally defined as older than 60 or 70, depending on the study) are on more than one medication due to multiple comorbidities, therapeutic drug treatment for older patients requires persistent vigilance and know-how, two experts…

Filed under:Conditions Tagged with:ACR Convergence 2020adverse drug reactionelderly

Diagnostic Drill-Down: New Research Suggests Genetic Autoinflammatory Roots

Mary Beth Nierengarten  |  January 25, 2021

Two experts discussed ongoing difficulties in diagnosing autoinflammatory disease, & promising new studies that point to possible genetic roots of autoinflammatory disease.

Filed under:ACR ConvergenceConditionsMeeting Reports Tagged with:ACR Convergence 2020autoinflammatory diseaseSAPHOSAPHO Syndromesystemic autoinflammatory diseases

ACR Convergence 2020

Interfering with Interferon: Experts Discuss IFN Signaling & IFN Inhibition Treatment Possibilities

Mary Beth Nierengarten  |  January 25, 2021

NIH investigators describe key features and genetic causes of Mendelian interferonopathies, & treatment approaches that may indicate the efficacy of IFN inhibition.

Filed under:ACR ConvergenceConditionsMeeting Reports Tagged with:ACR Convergence 2020interferonJAK inhibitorsjakinibsignaling

A Year to Remember: Dr. Jinoos Yazdany Presents the 2020 Clinical Research Review

Jason Liebowitz, MD, FACR  |  December 7, 2020

During ACR Convergence 2020, Jinoos Yazdany, MD, MPH, discussed innovative research into a potential treatment for lupus, medication tapering & more. These findings may influence the treatment of rheumatic disease in the future.

Filed under:ACR ConvergenceConditionsMeeting ReportsResearch Rheum Tagged with:ACR Convergence 2020anifrolumabaxial spondyloarthritis (SpA)Clinical researchCOVID-19GlucocorticoidsLupusrituximabVasculitis

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