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You are here: Home / Search for "Sarilumab"

Search results for: Sarilumab

Sarilumab Trial Data Shows It May Only Help Critical COVID-19 Patients

April 27, 2020 • By Saumya Joseph

(Reuters)—On April 27, Regeneron Pharmaceuticals Inc. and Sanofi SA said on Monday that their arthritis drug sarilumab (Kevzara) may only help the sickest patients with COVID-19, dampening hopes that the therapy could potentially reach a larger pool of patients with the disease. The drugmakers said they would test high doses of sarilumab only in critically… [Read More]

Filed Under: Drug Updates Tagged With: coronavirus, COVID-19, sarilumab, tocilizumab

Sarilumab Investigated to Treat COVID-19

March 23, 2020 • By Michele B. Kaufman, PharmD, BCGP

A study investigating sarilumab’s effects on patients with COVID-19 has begun in New York. The treatment blocks IL-6, which may play a role in the respiratory distress caused by the virus…... [Read More]

Filed Under: Drug Updates Tagged With: clinical trial, COVID-19, sarilumab

Can IL-6 Predict Sarilumab Response?

January 2, 2019 • By Michele B. Kaufman, PharmD, BCGP

Recent post-hoc analyses of two Phase 3 clinical trials show that RA patients with high interleukin 6 levels taking sarilumab experienced improved symptoms and less joint damage than those using other treatments…... [Read More]

Filed Under: DMARDs & Immunosuppressives, Drug Updates Tagged With: adalimumab, Methotrexate, sarilumab

News Updates for Diclofenac Sodium, Denosumab & Sarilumab

June 20, 2017 • By Michele B. Kaufman, PharmD, BCGP

In drug news, a generic 2% diclofenac sodium solution is now available, denosumab is promising to treat osteoporosis, and the FDA has approved sarilumab to treat adults with RA…... [Read More]

Filed Under: Biologics & Biosimilars, Drug Updates Tagged With: denosumab, diclofenac sodium, FDA, Food and Drug Administration, generic drugs, Knee Osteoarthritis (OA), Osteoporosis, Rheumatoid Arthritis (RA), sarilumab

Sarilumab Approval Stalled; Piclidenoson Promising for Psoriasis

November 16, 2016 • By Michele B. Kaufman, PharmD, BCGP

Due to manufacturing deficiencies found during a routine inspection by the FDA, approval of sarilumab for treating RA has slowed until facility issues are resolved…... [Read More]

Filed Under: Biologics & Biosimilars, Drug Updates Tagged With: apremilast, piclidenoson, Psoriasis, Rheumatoid Arthritis (RA), sarilumab

Sarilumab Is Effective for RA, Pregabalin Fails to Meet Study Endpoint & Ibuprofen Can Be Administered with a Patch

January 13, 2016 • By Michele B. Kaufman, PharmD, BCGP

Sarilumab is proving effective for treating RA. In a clinical trial, pregabalin did not meet its endpoint for treating post-traumatic peripheral neuropathic pain. And a 12-hour ibuprofen patch is in development…... [Read More]

Filed Under: Analgesics, Biologics & Biosimilars, Drug Updates Tagged With: Pain, peripheral neuropathic pain, pregabalin, Rheumatoid Arthritis (RA), sarilumab

What You Need to Know About COVID-19 & Therapies for Rheumatic Diseases

December 6, 2022 • By Jason Liebowitz, MD

PHILADELPHIA—Since March 2020, the world has been turned upside down by the COVID-19 pandemic. Rheumatologists must understand how to best protect and treat their patients with autoimmune conditions at risk for infection due to immunosuppressive therapy. At ACR Convergence 2022, the session titled, Latest COVID and Rheumatic Disease Therapies: What You Need to Know, provided… [Read More]

Filed Under: ACR Convergence, Conditions, Meeting Reports Tagged With: ACR Convergence 2022, COVID-19

New Findings for Polymyalgia Rheumatica & Osteoarthritis

December 1, 2022 • By Ruth Jessen Hickman, MD

The Plenary III Session reviewed the results of the SAPHYR trial of sarilumab in PMR patients, as well as the WE-CAN study on the impact of a community-level diet & exercise program on knee pain in patients with knee osteoarthritis.... [Read More]

Filed Under: ACR Convergence, Conditions, Meeting Reports Tagged With: ACR Convergence 2022, Osteoarthritis, polymyalgia rheumatica (PMR), sarilumab, weight loss

Never Too Late: Late-Breaking Abstracts Create Excitement

July 15, 2022 • By Jason Liebowitz, MD

EULAR 2022 (VIRTUAL)—The pace of scientific progress in research medicine is incredible and seems to only accelerate with time. Thus, the 2022 Congress of the European Alliance of Associations for Rheumatology (EULAR) session on late-breaking abstracts fittingly captured the excitement and timeliness of a number of research projects that have just recently been completed and… [Read More]

Filed Under: Conditions, Meeting Reports Tagged With: abstracts, baricitinib, Bimekizumab, deucravacitinib, EULAR, EULAR 2022, juvenile idiopathic arthritis (JIA), Methotrexate, orelabrutinib, polymyalgia rheumatica (PMR), Psoriatic Arthritis, sarilumab, systemic lupus erythematosus (SLE)

Conservation of Drugs: The Impact of Acute Immunomodulator Prescribing for COVID-19 on Rheumatology Patients

May 23, 2022 • By Sara Jo Santangelo, PharmD candidate, & Wendy Ramey, BSPharm, RPh, CSP

In its COVID-19 treatment guidelines, the National Institutes of Health (NIH) lists several drugs commonly prescribed for patients with rheumatic conditions as potential therapies in those who are hospitalized for COVID-19 and require high-flow oxygen, noninvasive ventilation, intermittent ventilation (IMV) or extracorporeal membrane oxygenation (ECMO), as of Aug. 25, 2021, and current as this is… [Read More]

Filed Under: Drug Updates, Interprofessional Perspective Tagged With: baricitinib, COVID-19, immunomodulatory agent, Interprofessional Perspective, sarilumab, tocilizumab, Tofacitinib

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