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Hip Exercises May Improve Walking, Pain with Knee Arthritis

Carolyn Crist  |  March 13, 2019

(Reuters Health)—Patients with knee osteoarthritis (OA) can add hip-strengthening exercises to their workout to improve the ability to walk and maybe reduce pain, according to a research review. Based on pooled data from eight clinical trials with a total of 340 patients, hip strengthening exercises involving weights or elastic bands would help the most, the…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:ExercisehipkneeKnee Osteoarthritis (OA)knee painwalkingweight training

Happiness in Rheumatology

Richard Quinn  |  March 12, 2019

A 2019 report says rheumatologists are the happiest medical specialists outside of work. Simon Helfgott, MD, says this finding shows “we have been able to blend an interesting, intellectually stimulating profession and practice with the ability to help people.”..

Filed under:Professional Topics

FDA Issues Boxed Warning for Febuxostat & Approves Colchicine for Gout Flare

Michele B. Kaufman, PharmD, BCGP  |  March 12, 2019

The FDA has issued a boxed warning for febuxostat after a safety study found an increased risk of heart-related and other death in RA patients…

Filed under:ConditionsDrug UpdatesGout and Crystalline Arthritis Tagged with:cardiovascularColchicineDrug SafetyFebuxostatFood and Drug AdministrationGoutSafetyU.S. Food and Drug Administration (FDA)

Metabolic Profiling of SLE

Lara C. Pullen, PhD  |  March 12, 2019

Research examining the metabolic profile of SLE found increased oxidative activity, as well as lower levels of tyrosine and tryptophan, in SLE patients relative to controls, suggesting increased activity of aromatic amino acid decarboxylase. The results suggest metabolomics may have the ability to measure disease severity in SLE…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:metabolismMetabolomic profileSLEsystemic lupus erythematosus (SLE)

Safety Risk with Higher Dose Tofacitnib

Michele B. Kaufman, PharmD, BCGP  |  March 6, 2019

According to the FDA, an ongoing safety trial found higher dose tofacitinib increased the risks of pulmonary embolism and death in RA patients…

Filed under:Drug Updates Tagged with:cardiovasculardeathDrug SafetyFood and Drug Administrationpulmonary embolismsafety warningTofacitinibU.S. Food and Drug Administration (FDA)

Rheumatoid Arthritis Risk Lower Among Smokers Who Quit

Lisa Rapaport  |  March 5, 2019

(Reuters Health)—Adults who quit smoking decades ago may have a lower risk of rheumatoid arthritis (RA) than people who gave up cigarettes more recently, a U.S. study suggests. Smoking has long been linked to an increased risk of RA, and quitting can reduce this risk. But the new study offers fresh evidence that years of…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:Arthritis Care & ResearchRheumatoid Arthritis (RA)riskSmoking

Practices Now Contributing to RheumPAC

Carina Stanton  |  March 5, 2019

Last year the ACR’s nonpartisan political action committee, RheumPAC, raised nearly $150,000 from individual contributors. Starting in 2019, the addition of the RheumPAC Advocacy Fund, where rheumatology practices and state societies can contribute corporate dollars, is expected to support RheumPAC fundraising efforts in an effort to surpass this dollar amount, giving rheumatology an even stronger…

Filed under:Legislation & AdvocacyPractice Support Tagged with:Kent “Kwas” Hustonrheumatology practicesRheumPACRheumPAC Advocacy FundZachary Wallace

Why Fellows Should Care about Advocacy

Blaine Lapin, MD  |  March 5, 2019

As a physician, I am an advocate. I am an advocate for my patients individually and collectively, and I am an advocate for my field: pediatric rheumatology. My own experiences as a patient drive me to integrate my patients’ perspectives into my medical decision making, and although my academic training has prepared me to best…

Filed under:Legislation & AdvocacyOpinionRheuminationsSpeak Out Rheum Tagged with:Fellows-in-TrainingRheumPAC

History of Depression Is a Risk Factor for SLE in Women

Carina Stanton  |  February 28, 2019

Results from a 20-year, cohort study add to the evidence that depression increases the risk of developing an autoimmune disease, specifically SLE in women. Lead investigator Andrea Roberts, PhD, says, “There may be direct biological effects of depression that increase the risk of autoimmune disease.”…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:Depressionriskrisk factorSLEsystemic lupus erythematosus (SLE)Women

Upadacitinib at the FDA

Michele B. Kaufman, PharmD, BCGP  |  February 28, 2019

Upadacitinib is an investigational, oral, small molecule JAK1-selective inhibitor, which recently completed phase 3 clinical trials for treating patients with moderate to severe rheumatoid arthritis (RA). In late 2018, AbbVie Inc. submitted a New Drug Application to the U.S. Food and Drug Administration, as well as a marketing authorization application to the European Medicines Agency,…

Filed under:Drug Updates Tagged with:FDARheumatoid Arthritis (RA)U.S. Food and Drug Administration (FDA)upadacitinib

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