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Search results for: interstitial lung disease

FDA Approves Tocilizumab to Treat Systemic Sclerosis-Associated ILD

Michele B. Kaufman, PharmD, BCGP  |  March 25, 2021

Subcutaneous tocilizumab is the first biologic agent approved by the FDA treat patients with systemic sclerosis-associated interstitial lung disease.

Filed under:Drug Updates Tagged with:FDAFDA approvalILDinterstitial lung disease (ILD)systemic sclerosis (SSc)systemic sclerosis-associated ILDtocilizumabU.S. Food and Drug Administration (FDA)

A Combined Immunosuppressive Regimen for ILD MDA5-Positive Dermatomyositis

Arthritis & Rheumatology  |  February 27, 2020

Interstitial lung disease accompanied by anti-melanoma differentiation-associated gene 5 positive dermatomyositis is often rapidly progressive and associated with poor prognosis. In this study, a combined immunosuppressive regimen of high-dose glucocorticoids, tacrolimus and intravenous cyclophosphamide proved more effective than treatment with high-dose glucocorticoids and stepwise addition of an immunosuppressant in a historical control group.

Filed under:ConditionsMyositisResearch Rheum Tagged with:Arthritis & Rheumatologydermatomyositis (DM)ILDinterstitial lung disease (ILD)Research

Catch Your Breath: Insights into ILD in RA Patients

Jason Liebowitz, MD, FACR  |  September 12, 2019

Detecting interstitial lung disease in RA patients can be challenging. But evaluating risk factors and the use of imaging can help clinicians identify and manage this condition in patients…

Filed under:ConditionsEULAR/OtherMeeting ReportsRheumatoid Arthritis Tagged with:EULARILDimagingInterstitial Lung DiseaseMethotrexateRheumatoid Arthritis (RA)Risk Factors

From the Expert: New Advances in Treatment of Systemic Scleroderma

Richard Quinn  |  April 22, 2016

A recent study found that mycophenolate mofetil is an effective alternative for the treatment of systemic scleroderma with interstitial lung disease, resulting in possible long-term improvement. According to Aryeh Fischer, MD, this new research points to the future expansion of treatment options…

Filed under:ConditionsSystemic Sclerosis Tagged with:cyclophosphamideInterstitial Lung Diseaselungmycophenolate mofetilSclerodermasystemic scleroderma

Fellow’s Forum Case Report: Diagnosing Antisynthetase Syndrome

Fawad Aslam, MBBS, and Elizabeth B. Russell, MD  |  May 1, 2013

A variable combination of interstitial lung disease, myopathy, fever, joint involvement, and mechanic’s hands characterize this systemic autoimmune syndrome

Filed under:ConditionsOther Rheumatic Conditions Tagged with:Antisynthetase SyndromeInterstitial Lung Diseasepatient care

Cilnidipine Receives Orphan Drug Status to Treat Systemic Sclerosis

Michele B. Kaufman, PharmD, BCGP  |  May 9, 2025

Based on research showing improved signs and symptoms of systemic sclerosis in patients taking cilnidipine vs. placebo, the FDA granted orphan drug designation for the agent.

Filed under:Biologics/DMARDsConditionsDrug UpdatesSystemic Sclerosis Tagged with:AISA-021cilnidipineFDASScsystemic sclerosis (SSc)U.S. Food and Drug Administration (FDA)

ACR Leaders Discuss Rheumatology Medications at Medicare Drug Price Negotiation Town Hall

From the College  |  May 2, 2025

On April 30, Rebecca Shepherd, MD, MBA, and Amanda Myers, MD, represented rheumatology in a live town hall on the Medicare Drug Price Negotiation Program, describing the benefits of apremilast and nintedanib for patients with rheumatic disease.

Filed under:InsuranceLegislation & Advocacy Tagged with:Advocacydrug pricesMedicare Drug Price Negotiation

Skin disorder, pepper appearance from scleroderma, autoimmune disease male hand Skin disorder pepper appearance from vitiligo,scleroderma raynaud, medical concept autoimmune disease. Credit: Adobe Stock | Trsakaoe

Through Thick & Thin: Updates in Scleroderma

Jason Liebowitz, MD, FACR  |  January 22, 2025

Pulmonary hypertension and Raynaud’s phenomenon are just some of the symptoms patients with systemic sclerosis (SSc) may experience. Here are insights into the diagnosis and management of SSc.

Filed under:ConditionsEULAR/OtherMeeting ReportsSystemic Sclerosis Tagged with:interstitial lung disease (ILD)pulmonary hypertensionRaynaud’s phenomenonSclerodermaSSc-ILDsystemic sclerosis (SSc)

Strong Argument: Recent Developments in Myositis Diagnosis & Care

Jason Liebowitz, MD, FACR  |  January 15, 2025

Lisa Christopher-Stine, MD, MPH, discussed the latest findings on myositis and its subtypes, including insights into antibodies linked to cancer and treatments for these patients.

Filed under:ConditionsEULAR/OtherMeeting ReportsMyositis Tagged with:Antisynthetase SyndromeCancerdermatomyositisDiagnosispatient carepolymyositis

MCTD: Is It Just Letters?

Ruth Jessen Hickman, MD  |  December 4, 2024

At a Great Debate session, speakers discussed whether mixed connective tissue disease is a distinct disease entity in rheumatology.

Filed under:ACR ConvergenceConditionsGuidanceMeeting ReportsOther Rheumatic Conditions Tagged with:ACR Convergence 2024connective tissue diseasemixed connective tissue disease (MCTD)

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