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Search results for: methotrexate

Case Study: Cerebral Toxoplasmosis in a Newly Diagnosed Lupus Patient

Komal Ejaz, MD, & Muhammad Ali Raza, MD  |  March 15, 2021

The occurrence of opportunistic infections is an established complication in patients diagnosed with systemic lupus erythematosus (SLE). The foremost challenge in such circumstances is differentiating between an exacerbation or progression of SLE, and the effects of the infection itself.1 Toxoplasma gondii is a ubiquitous parasite that often causes an asymptomatic infection in healthy, immunocompetent adults….

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:case reportcerebral toxoplasmosisInfectionToxoplasma gondii

In Memoriam: Shunle Chen, MD

Nan Shen, MD, PhD, & Peter E. Lipsky, MD  |  March 15, 2021

It is with great sadness that we report the passing of a giant of international rheumatology, Professor Shunle Chen. He was a friend, colleague, collaborator, visionary leader and inspiration to many rheumatologists in China and the world. Moreover, despite his inter­national stature, he was a warm friend and nurturing mentor to all those who had…

Filed under:Professional TopicsProfiles Tagged with:Dr. Shunle Chen

Neti Pots, Nurse Ambassadors & American Healthcare

Philip Seo, MD, MHS  |  March 15, 2021

Just YouTube it. As a rheumatologist who sees many patients with granulomatosis with polyangiitis (GPA), I have spent a significant portion of my life talking to people about neti pots. Originally, the neti pot was part of the Ayurvedic tradition. Neti pots were used to flush the sinuses with water, milk and ghee, or to…

Filed under:OpinionProfessional TopicsRheuminationsSpeak Out Rheum Tagged with:medication compliancenurse ambassadors

Health Canada Approves CT-P13 SC for RA; Plus Tofacitinib May Increase Cardiac & Cancer Risks

Michele B. Kaufman, PharmD, BCGP  |  March 5, 2021

In Canada, a subcutaneous formulation of CT-P13, which is biosimilar to infliximab, was approved to treat rheumatoid arthritis.

Filed under:Biologics/DMARDsConditions Tagged with:CanadaCT-P13Drug SafetyFDAinfliximabRheumatoid Arthritis (RA)Tofacitinib

Study Explores Palindromic Rheumatism to Predict RA Development

Ruth Jessen Hickman, MD  |  March 4, 2021

Research from Ellingwood et al. examines how often patients diagnosed with early RA experience episodic joint inflammation and describes characteristics that may result in RA development.

Filed under:ConditionsRheumatoid Arthritis Tagged with:Inflammatory arthritisPalindromic RheumatismRheumatoid Arthritis (RA)

Diet, Microbes & Inflammation: Unique Microbial Genetic Strains in Inflammatory Disease, Plus a Possible Arthritis Diet

Susan Bernstein  |  March 4, 2021

Experts at ACR Convergence 2020 addressed how diet & the body’s microbiome affect chronic diseases.

Filed under:ACR ConvergenceConditionsMeeting Reports Tagged with:ACR Convergence 2020Dietgut microbiotainflammationMicrobiome

The Character of Rheumatology Has Changed Over the Past 50 Years

Bruce Rothschild, MD  |  February 16, 2021

Camelot allegedly existed once upon a time in South Wales. The name was evoked again in the 1960s, but perhaps it is also applicable to the character of rheuma­tology in the halcyon days of the 1970s and 80s.  That’s not to belittle the world we now live in, with so many treatment options for our…

Filed under:OpinionQuality Assurance/ImprovementSpeak Out Rheum Tagged with:imagingphysical examSpeak Out RheumatologyTesting

Research Outlines Benefits of bDMARDs to Treat Early RA

Michele B. Kaufman, PharmD, BCGP  |  February 10, 2021

Sapart et al. suggest a combination of methotrexate and biologic disease-modifying anti-rheumatic drugs as induction therapy for patients with early RA may lead to long-term remission.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:biologic disease-modifying antirheumatic drugsbiologic DMARDscombination therapyearly RAmonotherapyRheumatoid Arthritis (RA)

Study Examines Tofacitinib’s Long-Term Cardiovascular Risk & More

Michele B. Kaufman, PharmD, BCGP  |  February 8, 2021

In a post-marketing safety study, tofacitinib did not prove non-inferior to tumor necrosis factor inhibitors when evaluated for its long-term effects on heart disease, malignancies and serious infections in RA patients.

Filed under:Drug Updates Tagged with:Cardiovascular diseaseHeart DiseaseriskTofacitinib

European Commission Approves Upadacitinib for Psoriatic Arthritis & Ankylosing Spondylitis

Michele B. Kaufman, PharmD, BCGP  |  February 4, 2021

In January, upadacitinib was approved for use in Europe as a 15 mg, once-daily dose to treat patients with psoriatic arthritis and ankylosing spondylitis.

Filed under:ConditionsDrug UpdatesPsoriatic Arthritis Tagged with:Ankylosing SpondylitisEuropean UnionPsoriatic Arthritisupadacitinib

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