Little is known about the immunopathogenic relationship between celiac disease and systemic autoimmune diseases, such as primary Sjögren’s syndrome and systemic sclerosis. But new research indicates that screening for celiac disease may benefit patients newly diagnosed with systemic autoimmune diseases, as well as supports the idea that celiac disease may accelerate the development of systemic autoimmune disease…
Celiac disease and gluten sensitivity are difficult to diagnose, but they affect multiple systems and are associated with other autoimmune diseases. Lan Chen, MD, PhD, believes better testing and clearer education will be a gamechanger for celiac patients…
Systemic lupus erythematosus (SLE) can present in many ways and can be difficult to diagnose. Its association with celiac sprue has been only rarely documented, but has appeared in several case reports. When presenting together, it can be difficult to distinguish the underlying disease, because SLE itself has been known to cause malabsorption. This case…
Celiac is an autoimmune disease with both gastrointestinal and neurological implications. A recent review examined the immunological research on celiac disease to date, detailing the role of T cells and the protein TG2 in disease pathology…
NEW YORK—Rituximab may be an effective treatment for recalcitrant dermatitis herpetiformis (DH), according to a recent case study. “DH is an autoimmune blistering disease which is commonly associated with celiac disease and can present with debilitating pruritic blisters on extensor surfaces,” explained Dr. Ron Feldman of Emory University School of Medicine. “The most common treatments…
(Reuters Health)—People with type 1 diabetes often develop other autoimmune disorders, such as thyroid and gastrointestinal diseases, and a recent study yields new information about this link. In the study, 27% of patients with type 1 diabetes had at least one other autoimmune disorder. But the new study also held some surprises about how early…
(Reuters Health)—People who feel ill after eating wheat, but who don’t have celiac disease, may finally have a biological explanation for their symptoms, a new study suggests. Researchers from the U.S. and Italy found that people who claim to have wheat sensitivity do have biological reactions to gluten proteins in wheat, rye and barley. It’s…
CHICAGO—Celiac disease—the gluten-induced illness that can be seen alongside rheumatic diseases—has been seen much more commonly over the past 20 years than it was previously, but the illness can come with questions that are not always straightforward, an expert said at the ACR’s State-of-the-Art Clinical Symposium. The disease, in which the small intestine becomes inflamed…
A retrospective study shows that some patients presenting for pediatric rheumatology evaluation test positive for celiac disease—some without showing any gastrointestinal manifestations. Treatment includes a gluten-free diet…
NEW YORK (Reuters Health)—Screening for celiac disease (CD) is important in patients newly diagnosed with type 1 diabetes (T1D) and in children presenting for rheumatology evaluation, according to a pair of new reports. In a systematic review, online June 15 in Pediatrics, Australian researchers found most cases of CD are diagnosed within five years of…