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Search results for: abatacept

Abatacept Shows Promise for Some Myositis Patients

Deborah Levenson  |  May 12, 2025

Injected abatacept may be a worthwhile treatment for certain patients with idiopathic inflammatory myositis (IIM), according to recent research.1 Patients with the rare autoimmune conditions involving inflammation of muscle (myositis) and other organ systems suffer widespread organ dysfunction, increased morbidity, physical disabilities and early death. Symptoms vary by subtype. For example, dermatomyositis (DM) involves muscle…

Filed under:Biologics/DMARDsConditionsDrug UpdatesMyositisResearch Rheum Tagged with:abataceptAC&Ridiopathic inflammatory myositis

Upadacitinib Receives Breakthrough Designation, Abatacept Use Expands in Australia & More

Michele B. Kaufman, PharmD, BCGP  |  January 31, 2018

The FDA has designated upadacitinib a breakthrough therapy to treat adults with moderate to severe atopic dermatitis…

Filed under:ConditionsDrug UpdatesPsoriatic Arthritis Tagged with:abataceptAddictionaddiction treatmentbuprenorphineCAM2038Psoriatic ArthritisU.S. Food and Drug Administration (FDA)upadacitinib

Abatacept Approved for Psoriatic Arthritis in Adults; Sirukumab Approval Stalls

Michele B. Kaufman, PharmD, BCGP  |  September 17, 2017

Abatacept Approved for Adult PsA On June 30, the U.S. Food and Drug Administration (FDA) approved abatacept (Orencia) to treat adults with active psoriatic arthritis (PsA).1 Abatacept is available as both an intravenous formulation and a subcutaneous injection.2 The approval was based on results of two randomized, double-blind, placebo-controlled trials, PsA-I and PsA-II, during which…

Filed under:ConditionsDrug UpdatesResearch Rheum Tagged with:apataceptApprovalsClinicaldrugFDAMedicationOrenciaoutcomePsoriatic ArthritisRAResearchRheumatoid arthritisrheumatologySafetysirukumabstudyTreatmenttrial

Abatacept Plus Prednisone Therapy Studied for Treating Giant Cell Arteritis

Linda Childers  |  September 17, 2017

A recent study, conducted by the Vasculitis Clinical Research Consortium and funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), examined whether the addition of abatacept, a drug that affects T cell activation, to standard prednisone treatment could reduce the risk of relapse in patients with giant cell arteritis (GCA).1 Although…

Filed under:ConditionsResearch RheumVasculitis Tagged with:abataceptACR Journal ReviewAmerican College of Rheumatology (ACR)Giant Cell ArteritisGlucocorticoidspatient careprednisonerelapseResearchrheumatologyriskSteroidT celltherapyTreatmentVasculitis

Abatacept Approved for Adult PsA

Michele B. Kaufman, PharmD, BCGP  |  July 31, 2017

The FDA has approved abatacept to treat adults with active psoriatic arthritis. In clinical trials, the treatment has proved effective in both intravenous and subcutaneous forms…

Filed under:ConditionsDrug UpdatesPsoriatic Arthritis Tagged with:abataceptFDAFood and Drug AdministrationPsoriatic ArthritisU.S. Food and Drug Administration

FDA Requests Removal of Opana ER; Plus Abatacept’s New Dosing Option

Michele B. Kaufman, PharmD, BCGP  |  June 21, 2017

The FDA has asked the manufactures of Opana ER to remove the opioid from the U.S. market due to the public health risk of abuse…

Filed under:AnalgesicsBiologics/DMARDsDrug Updates Tagged with:abataceptFDAFood and Drug Administrationjuvenile idiopathic arthritis (JIA)Opana EROpioid abuseOpioidspolyarticular arthritispublic healthSafety

Similar RA Outcomes with Abatacept & Tocilizumab

Will Boggs, MD  |  August 17, 2015

NEW YORK (Reuters Health)—Clinical outcomes of rheumatoid arthritis (RA) are similar with abatacept and tocilizumab treatment, but the factors that predict efficacy differ for the two agents. “The recommendations for RA treatment from the U.S. and EU describe the use of abatacept and tocilizumab as first-line biologics along with anti-TNF (anti-tumor necrosis factor) inhibitors,” Dr….

Filed under:Biologics/DMARDsConditionsDrug UpdatesRheumatoid Arthritis Tagged with:abataceptBiologics & BiosimilarsRheumatiod arthritistocilizumab

Highlights from the European Congress of Internal Medicine

Vanessa Caceres  |  July 10, 2025

An overview of highlights from the 2025 ECIM meeting, including research on treatment options for systemic sclerosis, the management of PMR & autoimmune testing.

Filed under:ConditionsMeeting ReportsOther Rheumatic ConditionsSystemic Lupus Erythematosus Tagged with:abataceptCAR-T cell therapyEuropean Congress of Internal MedicineGiant Cell ArteritisGlucocorticoidsInterstitial Lung DiseaseMethotrexatenintedanibPolymyalgia Rheumaticarituximabserological testingstem cell transplantationSystemic sclerosis

Cancer cells

Cancer & RA Drugs: Are Some Drugs Riskier than Others?

Samantha C. Shapiro, MD  |  February 4, 2025

Sendaydiego et al. asked: Do some DMARDs pose a greater cancer risk than others for patients with RA? Here are insights from the study and its clinical implications.

Filed under:ConditionsDrug UpdatesRheumatoid Arthritis

Sunrise, Sunset: A Look Back on the Year in Rheumatology

Jason Liebowitz, MD, FACR  |  December 4, 2024

At the ACR Convergence 2024 Year in Review lecture, experts discussed advancements in disease understanding and treatments, as well as in basic science.

Filed under:ACR ConvergenceConditionsGout and Crystalline ArthritisGuidanceMeeting ReportsOsteoarthritis and Bone DisordersRheumatoid Arthritis Tagged with:ACR Convergence 2024ACR Convergence 2024 goutACR Convergence 2024 RAcardiovascularGoutKnee Osteoarthritis (OA)osteoarthritis (OA)preventionRheumatoid Arthritis (RA)

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