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You are here: Home / Search for "anti-phospholipid antibodies"

Search results for: anti-phospholipid antibodies

‘Nothing but NET[osis]’: RheumMadness 2022 Anti-NET Antibodies Scouting Report

February 8, 2022 • By The UNC Rheumatology Fellowship Program: Leah Bettner, MD; Shruti Chandramouli, MD; Christopher Overton, MD; Astia Allenzara, MD; Michael Cunningham, MD; & Luis Palomino, MD

Neutrophil extracellular traps (NETs) contribute to the pathogenesis of multiple autoimmune diseases. And research has shown that patients with antiphospholipid syndrome (APS) have higher levels of circulating anti-NET antibodies than healthy controls, indicating a potential biomarker.... [Read More]

Filed Under: Conditions, Research Reviews Tagged With: anti-NET antibodies, Antiphospholipid Antibody Syndrome (APS), APS, cells, NETosis, neutrophil extracellular traps, RheumMadness

Case Report: Lupus Nephritis or a Mimic?

November 10, 2022 • By Matthew J. Mandell, DO, Yishui Chen, MD, Prerna Rastogi, MD, PhD, & Rebecca Tuetken, MD, PhD

Syphilis, an ancient disease caused by the spirochete Treponema pallidum, has been historically referred to as the great mimicker given its heterogenous presentation. Both systemic lupus erythematosus (SLE) and syphilis can have multi-systemic involve­ment. Both parvovirus B19 and syphilis have been reported to cause histologic features similar to those seen in lupus nephritis.  We present… [Read More]

Filed Under: Conditions, SLE (Lupus) Tagged With: case report, Fellows, Fellows-in-Training, Lupus nephritis, parvovirus B19, SLE Resource Center, syphilis

Pregnancy Outcomes in Women with Idiopathic Inflammatory Myositis

April 8, 2019 • By Lara C. Pullen, PhD

New data from India suggest women with idiopathic inflammatory myositis are at increased risk of poor fetal outcomes and spontaneous abortions. In the study, researchers found these women had worse obstetric outcomes and increased risk of fetal complications…... [Read More]

Filed Under: Conditions Tagged With: birth, idiopathic inflammatory myositis, Outcomes, pregnancy, pregnant women

Lupus Patient Develops Miller Fisher Variant of Guillain-Barré Syndrome

October 18, 2018 • By Sedrick Bradley, MD, & Nirupa J. Patel, MD

Systemic lupus erythematosus (SLE) is a heterogeneous, auto­immune, inflammatory, connective tissue disease affecting multiple organs. Neither central nervous system nor peripheral nervous systems are spared. The neurologic system is involved in a wide range of 10–80% of patients with SLE. Peripheral neuropathy, such as Guillain-Barré syndrome (GBS) and its variants, can occur in neurologic complications… [Read More]

Filed Under: Conditions, SLE (Lupus) Tagged With: areflexia, ataxia, Guillain-Barré Syndrome, Miller Fisher Syndrome, ophthalmoplegia

APS: What Rheumatologists Should Know about Hughes Syndrome

February 17, 2016 • By Graham R.V. Hughes, MD, FRCP

The problem that dogs the work of all of those treating patients with antiphospholipid syndrome (APS) is the apparent lack of knowledge of the syndrome, both by the general public, as well as by swaths of the medical fraternity. Perhaps it was ever thus—a syndrome less than 40 years old could be described as new,… [Read More]

Filed Under: Conditions, Systemic Inflammatory Syndromes Tagged With: Antiphospholipid Antibody Syndrome (APS), brain, Clinical, Diagnosis, Hughes Syndrome, joint, miscarriage, patient care, pregnancy, rheumatologist, stroke, symptom, thrombosis

Rheumatology Case Report: Chondromyxoid Fibroma of the Sternum

February 16, 2016 • By Rajaie Namas, MD, Reshma Khan, MD, & Bernard Rubin, DO

A 47-year-old Caucasian woman presented to the rheumatology clinic with a one-year history of pain and swelling involving the wrists, hands, ankles and feet that progressively worsened. Her symptoms included generalized fatigue, morning stiffness in the hands and lower back lasting more than an hour, Raynaud’s phenomena (triphasic), photosensitivity, tightening of the skin of the… [Read More]

Filed Under: Conditions, Scleroderma Tagged With: Autoimmune disease, chondromyxoid fibroma, Clinical, Diagnosis, outcome, patient care, rheumatology, Scleroderma, sternum

A Young Disease: A Holistic Approach to the Treatment of Antiphospholipid Syndrome

September 8, 2022 • By Samantha C. Shapiro, MD

Although progress has been made in recent years, rheumatologists still have a lot of questions regarding best management practices for antiphospholipid syndrome (APS). During a session of EULAR 2022, Ricard Cervera, MD, PhD, described a holistic approach. ... [Read More]

Filed Under: Conditions, Meeting Reports Tagged With: antiphospholipid syndrome, cardiovascular, catastrophic antiphospholipid syndrome, EULAR 2022, Glucocorticoids, patient care

Promote Pregnancy Wellness: Data Can Help Guide Pregnancy Management in Lupus

September 10, 2018 • By Thomas R. Collins

AMSTERDAM—Clinicians who are counseling women with systemic lupus erythematosus (SLE) have the benefit of an array of new insights into factors linked with increased risk of pregnancy loss, how SLE therapies affect pregnancy and data on outcomes of children born to mothers with SLE, an expert said in a session at EULAR: the Annual European… [Read More]

Filed Under: Conditions, SLE (Lupus) Tagged With: HYDROXYCHLOROQUINE, Lupus nephritis, pregnancy, pregnant women, systemic lupus erythematosus (SLE)

Case Report: Refractory Calciphylaxis in Lupus

May 17, 2018 • By Joey Kim, MD, Navneet Kaur, MD, Phillip Zhang, MD, & Irene Blanco, MD, MS

Calciphylaxis is a poorly understood and life-threatening ischemic vasculopathy characterized by calcification of the small- and medium-size arteries in the skin, subcutaneous tissue and internal organs, which leads to thrombosis, tissue necrosis and painful skin ulcerations that won’t heal. The disease has a 50–80% mortality rate. Although affected patients typically have end-stage renal disease (ESRD)… [Read More]

Filed Under: SLE (Lupus) Tagged With: calciphylaxis, connective tissue disease, Systemic lupus erythematosus

New Rheumatology Disease Research & Advice

February 17, 2018 • By Thomas R. Collins

SAN DIEGO—Top researchers gathered for a review course at the start of the 2017 ACR/ARHP Annual Meeting in November to describe new research, their own treatment strategies and new ways of thinking about an array of rheumatic diseases. Here are the highlights: Raynaud’s & Other Digit Problems When a patient walks into your clinic with… [Read More]

Filed Under: Meeting Reports, Osteoarthritis, Rheumatoid Arthritis, Scleroderma, Spondyloarthritis, Vasculitis Tagged With: ACR/ARHP Annual Meeting, adhesive capsulitis, ANCA, axial spondyloarthritis (SpA), diabetes, Dry eye, Ethics, lung disease, meniscus surgery, Osteoarthritis, Raynaud's, red eye, Rheumatoid arthritis, scleritis, Vasculitis

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