A recent study analyzed inflammasome response, finding the POP1 PYRIN domain protein acts to decrease excessive inflammatory responses and prevent systemic inflammation. Researchers ultimately developed a drug based on POP1 and found it reduced inflammation in mice…
Lara C. Pullen, PhD, is a medical writer with a PhD in microbiology/immunology from Northwestern University’s Feinberg School of Medicine. As a medical writer she has covered topics as diverse as diabetes, cardiovascular disease, and autism. Her favorite subject, however, is the role of the immune system in health and disease. Dr. Pullen is also the mother of three children, the youngest of whom has Prader-Willi Syndrome (PWS). She is an active member of the PWS community and a thought leader on the importance of the ketogenic diet for this patient population.
Articles by Lara C. Pullen, PhD
Peripheral Nerve Regeneration Insights
A recent investigation provides new details on how macrophages, endothelial cells and Schwann cells coordinate to heal peripheral nerve damage…
Understanding SLE-Associated Skin Injury May Open the Door to Therapies
In a recent review, researchers addressed skin injury in patients with SLE, discussing the effects of ultraviolet rays on the skin and the subsequent generation of autoantibodies. They concluded that UV rays activate immune cells where IgG has been deposited, resulting in inflammation…
Early, Aggressive Therapy for RA May Result in Cost Savings Long Term
By considering the long-term damage from early, aggressive rheumatoid arthritis, researchers in the UK were able to develop a model demonstrating the long-term cost effectiveness of more aggressive combination therapies v. short-term treatments…
Vitamin C Derivative Promising Option for OA
New research in mice has found that treatment with a vitamin C derivative can effectively suppress the generation of mitochondrial superoxide, which plays a role in cartilage degeneration and the progression of osteoarthritis…
Intensive Program Relieves Symptoms of Juvenile Fibromyalgia
Pain can be reduced and functionality significantly improved for children with fibromyalgia without drug therapy, according to a study of 64 children in Philadelphia. Researchers combined intensive physical therapy and psychotherapy in individualized programs to treat the fibromyalgia patients…
Reducing Gout Flare Frequency Saves Money
A new data-driven study tracked and analyzed gout-related healthcare costs for more than three years, determining the financial burden of flares and the possible benefit of proper flare management…
Varicella Zoster Virus May Cause Giant Cell Arteritis
Researchers have recently discovered a connection between the varicella zoster virus infection, which causes chicken pox and shingles, and giant cell arteritis…
T Cell Exhaustion: A New Strategy for Treating Autoimmune Disease
Researchers in the U.K. have discovered that manipulating T cells to exhaustion in a targeted way may lead to new treatments and predictors for various types of autoimmune diseases…
New Study Examines Pregnancy Risk Factors for Patients with Lupus
Important new findings show that a majority of women with inactive or stable SLE can have successful pregnancies without experiencing flares and give birth to infants who survive the neonatal period…
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