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Biologics/DMARDs

Mirikizumab Promising for Plaque Psoriasis

Michele B. Kaufman, PharmD, BCGP  |  April 10, 2019

During a 16-week study, patients with plaque psoriasis taking mirikizumab experienced higher response rates and skin clearance compared with placebo…

Health Canada Approves Adalimumab for Chronic Non-Infectious Anterior Uveitis in Pediatric Patients

Michele B. Kaufman, PharmD, BCGP  |  April 3, 2019

Health Canada has approved adalimumab for treating chronic non-infectious anterior uveitis in patients 2 years and older…

FDA Approves Guselkumab Injector

Michele B. Kaufman, PharmD, BCGP  |  March 20, 2019

The FDA has approved a single-press, self-injection device for a 100-mg dose of guselkumab for adults with moderate to severe plaque psoriasis…

Biosimilars: How Do They Affect Patient Care & Safety?

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—“We have got to get over this hump. We have got to try new stuff,” said Jacqueline M. Fritz, RN, MSN, CNS, to the audience gathered on the final day of the 2018 ACR/ARHP Annual Meeting, referring to the subject of biosimilars. Ms. Fritz, the owner and coordinator of education at the Medical Advancement Center…

WindNight / shutterstock.com

Why & How Our Biologic Drug Discussion with Patients Should Evolve

Paul H. Caldron, DO, PhD, MBA, & John R.P. Tesser, MD  |  February 17, 2019

As we turn the corner on the second decade of biologic use for rheumatic disorders, a reappraisal of approach in our communication with patients is due. In practice, the impact these agents have on patients’ lives justifies the friction rheumatologists face when connecting patients to them. You can understand why older rheumatologists who apprenticed on…

Biosimilar ABP 798 Promising for RA

Michele B. Kaufman, PharmD, BCGP  |  February 13, 2019

A clinical trial in RA patients has established the pharmacokinetic similarity of ABP 798 and rituximab…

FDA Approves Rituximab Biosimilar; Plus New Safety Data for Filgotinib in RA Patients

Michele B. Kaufman, PharmD, BCGP  |  January 7, 2019

The FDA has approved Truxima (rituximab-abbs), which is biosimilar to Rituxan (rituximab), for treating adults with CD20-positive, B-cell non-Hodgkin’s lymphoma…

VA Study Tracks Biologics Usage, Finds Dramatic Patient-Age Difference

Catherine Kolonko  |  December 17, 2018

Patients under the care of the U.S. Veterans Affairs who were older, non-white and had more comorbidities were less frequently given biologic initiation therapy to treat their rheumatoid arthritis (RA), according to a recent study. Researchers sought to identify predictors of greater use of biologic therapies, as well as factors associated with persistent use of…

5-Year Data on Secukinumab in AS; Oliceridine Not Recommended for FDA Approval

Michele B. Kaufman, PharmD, BCGP  |  November 7, 2018

In a long-term study, secukinumab proved safe and effective for treating ankylosing spondylitis…

Ixekizumab Improves Outcomes of Ankylosing Spondylitis

Will Boggs, MD  |  November 5, 2018

NEW YORK (Reuters Health)—Ixekizumab improves signs and symptoms in patients with radiographic axial spondyloarthritis (ankylosing spondylitis), according to results from the COAST-W study. “Ankylosing spondylitis is a chronic and debilitating disease, and I have a large number of patients who have failed TNF inhibitors,” says Dr. Atul Deodhar from Oregon Health and Science University, Portland….

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