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Search results for: tocilizumab

Sarilumab Investigated to Treat COVID-19

Michele B. Kaufman, PharmD, BCGP  |  March 23, 2020

A study investigating sarilumab’s effects on patients with COVID-19 has begun in New York. The treatment blocks IL-6, which may play a role in the respiratory distress caused by the virus…

Filed under:Drug Updates Tagged with:clinical trialsCOVID-19sarilumab

Enemy at the Gates: The Emerging Threat of COVID-19

Philip Seo, MD, MHS  |  March 23, 2020

On Dec. 30, 2019, an ophthalmologist named Li Wenliang notified his colleagues about an illness that was reminiscent of severe acute respiratory syndrome (SARS) in a city in the Hubei province of China called Wuhan. As an ophthalmologist, this was not directly relevant to his practice; he merely wanted to warn colleagues that they might…

Filed under:ConditionsOpinionProfessional TopicsRheuminationsSpeak Out Rheum Tagged with:COVID-19Philip SeoRheuminationsSeo

Don’t Forget the Host: COVID-19 Cytokine Storm

Randy Q. Cron, MD, PhD, & W. Winn Chatham, MD  |  March 16, 2020

The new coronavirus outbreak, COVID-19, reminds us how we have struggled to keep ahead of mutating pathogens through the ages.

Filed under:Conditions Tagged with:COVID-19

Pediatric Cases Require Special Considerations & Aggressive Treatment Plans

Thomas R. Collins  |  March 12, 2020

ATLANTA—Managing pediatric patients with rheumatic disease involves special considerations, such as developmental concerns and physiological traits that may affect dosing of medications, according to two experts. During a session at the 2019 ACR/ARP Annual Meeting, Courtney Kremer, ARNP, a pediatric nurse practitioner at the University of Iowa Stead Family Children’s Hospital, Iowa City, and Jessica…

Filed under:Biologics/DMARDsConditionsMeeting ReportsPediatric Conditions Tagged with:2019 ACR/ARP Annual Meetingjuvenile idiopathic arthritis (JIA)

FDA Update: New Drug Approvals, New & Expanded Indications, & More

Susan Bernstein  |  March 12, 2020

ATLANTA—New drug approvals, new and expanded drug indications, and important safety and other updates relevant for rheumatologists were presented by three physicians from the U.S. Food & Drug Administration (FDA) on Nov. 11 at the 2019 ACR/ARP Annual Meeting. New JAK Inhibitor Approved for RA On Aug. 16, 2019, the FDA approved upadacitinib (Rinvoq), an…

Filed under:Biologics/DMARDsDrug UpdatesMeeting Reports Tagged with:2019 ACR/ARP Annual MeetingapremilastCertolizumab PegolFebuxostatixekizumabJAK inhibitorsnintedanibrituximabU.S. Food and Drug Administration (FDA)upadacitinib

Thoughtful Pediatric Care: Pediatric Cases Require Special Considerations & Aggressive Treatment Plans

Thomas R. Collins  |  March 9, 2020

In Canada, five provinces will now reimburse patients with plaque psoriasis who use risankizumab. Also, Canada Health has approved apremilast for treating adults with plaque psoriasis and psoriatic arthritis…

Filed under:Conditions Tagged with:2019 ACR/ARP Annual Meetingpediatric arthritisPediatric RheumatologyPediatrics

Pearls & Myths: Experts Offer Advice & Dispel Myths

Thomas R. Collins  |  February 25, 2020

GCA, GPA, myositis, new research—rheumatology care keeps clinicians on their toes & requires them to stay up to date…

Filed under:CareerCareer DevelopmentMeeting ReportsProfessional Topics Tagged with:2019 ACR/ARP Annual Meeting

FDA Rheumatology Update: New Drug Approvals, Plus Expanded Drug Indications & Safety Concerns

Susan Bernstein  |  February 12, 2020

Last year, the FDA was busy with new biologic and other drug approvals, new and expanded drug indications, and important safety updates relevant to rheumatology…

Filed under:Drug Updates Tagged with:2019 ACR/ARP Annual MeetingBiologicsFDAU.S. Food and Drug Administration (FDA)

Varicella Zoster Virus Not Associated with Giant Cell Arteritis Pathogenesis

Carina Stanton  |  February 4, 2020

Researchers suggest antiviral therapy is not appropriate for patients with GCA, based on their study findings and related research…

Filed under:ConditionsVasculitis Tagged with:GCAgiant cell arteritis (GCA)varicella zoster virus

Update on the Management of Takayasu Arteritis

Lara C. Pullen, PhD  |  February 4, 2020

A rare form of large vessel vasculitis, Takayasu arteritis persents with no clear patterns, with patients experiencing vascular symptoms, as well as such systemic symptoms as fever and weight loss. A systematic literature review found evidence to guide rheumatologists in monitoring and treating their patients with Takayasu arteritis…

Filed under:ConditionsVasculitis Tagged with:large-vessel vasculitisTakayasu’s ArteritisVasculitis

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