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Search results for: axial spondyloarthritis

Difficult-to-Manage Spondyloarthritis

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Studies show that patients with difficult-to-treat axial spondyloarthritis had more disease activity and greater peripheral involvement, with extra musculoskeletal manifestations and fibromyalgia. The ACR Convergence 2024 session on Difficult-to-Manage Spondyloarthritis will focus on patients for whom first- and second-line therapies have failed or who have persistent extra-axial manifestations of disease despite these treatment options. The…

Data Accumulate to Suggest HLA-B27 Status May Drive Axial Phenotype in SpA

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HLA-B27 may be a phenotypic expression of axial spondyloarthritis (SpA), according to a large international study. The study found patients with axial SpA who were positive for HLA-B27 had more severe radiographic damage than those who were negative for HLA-B27, and three quarters of study patients with ankylosis spondyloarthritis were HLA-B27 positive.

Imaging of Axial Psoriatic Arthritis

Walter P. Maksymowych, MB ChB, FACP, FRCP(C)  |  

The axial phenotype of psoriatic arthritis (axPsA) is an excellent example of a major controversy in rheumatology that has become the focus of attention because of the emergence of new therapies with different mechanisms of action for alleviating joint inflammation. It was first described in 1961 but, until recently, it has largely remained under the…

Axial Disease in Psoriatic Arthritis

Philip Helliwell, DM, PhD, FRCP  |  

When Moll and Wright first described the spondyloarthritides in the early 1970s, the archetype of the group was ankylosing spondylitis (AS).1 The shared clinical features of the spondyloarthritides were sacroiliitis; asymmetric large joint peripheral arthritis; psoriasis or psoriaform skin lesions, including keratoderma blennorrhagica; uveitis; and bowel inflammation. Moll and Wright described five clinical subgroups of…

In the Bones: RheumMadness 2022 False Positive MRI in Axial SpA

University of South Florida Rheumatology Fellowship Program: Anastasiya (Stacy) Bagrova, MD; Shreya Gor, MD; Joanne Valeriano-Marcet, MD; Larry Young, MD; & John Carter, MD  |  

Spondyloarthropathy (SpA) can be difficult to diagnose, with rheumatologists sometimes relying on classification criteria designed for clinical trials. Research examines how the use of MRIs affects the finding of bone marrow edema and the diagnosis of axial SpA.

How Do Axial SpA & PsA with Axial Involvement Differ?

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The differences between axial spondyloarthropathy (axSpA) and axial involvement in psoriatic arthritis (axPsA) have clinical and therapeutic implications. Three experts discussed the distinctions during ACR Convergence 2021.